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Traumatic Brain Injury (TBI) is a prevalent form of neurological damage that may induce varying degrees of cognitive dysfunction in patients, consequently impacting their quality of life and social functioning. This article provides a mini review of the epidemiology in Chinese TBI patients and etiology of cognitive impairment. It analyzes the risk factors of cognitive impairment, discusses current management strategies for cognitive dysfunction in Chinese TBI patients, and summarizes the strengths and limitations of primary testing tools for TBI-related cognitive functions. Furthermore, the article offers a prospective analysis of future challenges and opportunities. Its objective is to contribute as a reference for the prevention and management of cognitive dysfunction in Chinese TBI patients.

We investigate the photovoltaic behaviors of magnetic graphene interconnect junctions, which are constructed by zigzag graphene nanoribbons (ZGNRs), with the aim to produce pure spin current by photogalvanic effect (PGE). Two kinds of interconnect junctions are designed by connecting two 6-ZGNR with a carbon hexagon (C6) and a carbon tetragon (C4), respectively. It is found that zero charge current is produced under irradiation of light in both structures due to the presence of spatial inversion symmetry. Nevertheless, behind the zero charge current, net pure spin current is produced in the structure with a C6, but not in the structure with a C4. This difference originates from their different edge state distribution and different spatial inversion symmetry of the spin density. However, interestingly, local edge pure spin current can be obtained in both structures. More importantly, the pure spin current generation is independent of the photon energy, polarization type or polarization angle, suggesting a robust way of generating pure spin current with PGE and new possibility of graphene’s applications in spintronics.

Plastic recycling is the most effective way to solve plastic pollution. Color recognition of plastic is a key step in the plastic recycling process, which is very important for improving the utilization rate of waste plastic. At present, the manual recognition method is inefficient and cannot meet the requirements of large-scale production, while the existing color recognition based on machine vision has problems such as low recognition accuracy of similar colors, complicated algorithm and high system cost. According to the above problems, a color recognition method based on multi-wavelength transmission spectrum was proposed in this paper for the color recognition of colorless, light blue, light green and apple green transparent plastic. For each transparent plastic, the transmission spectra at 381 nm, 439 nm, 620 nm and white transmission light source were obtained, and the ratios of R, G and B wavebands of the transmission spectra were used to set up a color feature, which was then used for color recognition. A color recognition model was established based on the color features and naive Bayes model. The 10-fold cross-validation results showed that the recognition accuracy of the four colors of transparent plastic reached 100%.

Near-infrared spectroscopy has become an important methodology for rapid and non-destructive detection in food and agricultural fields. However, the accuracy of quantitative analysis was seriously restricted by the severe overlap of spectra and the high cost of standard samples. In order to reduce the impact of these problems especially that of small sample size problem, a novel method named weighted clustering ensemble partial least squares (WCE-PLS) is proposed for the protein content analysis of corn. Firstly, the clustering and sampling strategy is introduced in the calibration sets of corn to create different subsets for generating sub-models. Then, root mean square errors of cross-validation (RMSECV) in those sub-models as the crucial criterion are computed for model optimization. Finally, in integrating step, two Gaussian weighted functions used to determine the weights of sub-models are defined. The validation performance of the proposed method is tested with the near infrared spectral data sets of corn and compared with single PLS, bagging PLS, boosting PLS, and data augmentation (DA) PLS. To further demonstrate the effectiveness of the method, another data set of soil was used for supplementary verification. Results of the prediction sets indicated that the RMSEP values of the WCE-PLS are obviously smaller than that of boosting PLS. And the RMSEP of WCE-PLS and bagging PLS is relatively small in most cases. Furthermore, the correlation coefficients between predicted value and chemical value are respectively 0.96587 and 0.90849 for two data sets, which computed by the WCE-PLS is obviously higher than that computed by the other four methods. And the t test also showed the WCE-PLS has smaller t values and larger p values.

In order to study the differential diagenesis of sandy conglomerate reservoirs in different tectonic units in eastern Junggar Basin, and establish the differential temporal sequence of burial – diagenesis – hydrocarbon charging – pore evolution, the Upper Permian Wutonggou Formation sandy conglomerate reservoir in the Dongdaohaizi Sag and Baijiahai Uplift, eastern Junggar Basin are studied, based on observation of thin sections under microscope, measurement of scanning electron microscopy (SEM), X-ray diffraction (XRD), physical properties, cathodoluminescence (CL), micro beam fluorescence, and analysis of fluid inclusions, combined with previous research results. The result shows that the reservoir displays a differential diagenetic process as they are situated at different tectonic units of the Dongdaohaizi Sag and the Baijiahai Uplift. The Dongdaohaizi Sag is dominated by continuous subsidence, the reservoir buried in relatively deep depths experienced three stages of hydrocarbon charging, which is more strongly affected by compaction, fracturing, dissolution, and late-stage cementation, the effect of middle-stage cementation is relatively weak. The pore evolution experienced four stages, including decreased porosity by shallow burial compaction, decreased porosity by moderate burial compaction and middle-stage cementation, decreased and increased porosity by moderate to deep burial middle-stage cementation and dissolution, and increased and decreased porosity by deep burial dissolution and late-stage cementation. The diagenetic stage had reached A sub-stage of mesodiagenesis, and the present porosity is relatively low; however, the developed structural fractures in the reservoir has played a good role in improving the reservoir seepage capacity. By contrast, the Baijiahai Uplift is characterized by multi-stage uplift, the reservoir buried in relatively shallow depths experienced two stages of hydrocarbon charging, which is more strongly affected by middle-stage cementation, with relatively weak compaction and dissolution, fracturing, and late-stage cementation was limited. The pore evolution experienced three stages, including decreased porosity by shallow burial compaction, decreased porosity by moderate burial compaction and middle-stage cementation, and decreased and increased porosity by moderate-deep burial middle-stage cementation and dissolution. The diagenetic stage has reached A sub-stage of mesodiagenesis, and the present porosity is relatively high. Two types of favorable reservoirs are developed in the study area. The first one is matrix pore favorable reservoir, which is mainly located in the area of the Baijiahai Uplift of the reservoir with relatively high porosity and permeability. The second one is structural fracture developed favorable reservoir, which is mainly located in the fault development area of the Dongdaohaizi Sag.

Polycystic ovary syndrome (PCOS) is one of the modern intractable reproductive diseases. The female irregular menstruation, infertility, obesity, and so forth caused by PCOS have become a hot issue affecting family harmony and social development. The aetiology of PCOS is complex. In recent years, many scholars have found that its pathogenesis was related to the imbalance of gut microbiota. Gut microbiota can form two‐way communication with the brain through the ‘gut‐brain axis’ and affect the host's metabolism. Current research has confirmed that the gut microbiota can interfere with glucose and lipid metabolism, insulin sensitivity, hormone secretion and follicular development in women by altering intestinal mucosal permeability and secreting metabolites. In addition, the diversity and composition of gut microbiota of PCOS patients changed, which may affect the metabolic function of the gut microbiota and the ability to produce metabolites, and may also directly or indirectly affect the endocrine function. This study reviewed recent research advances about the role of gut microbiota in PCOS. In order to provide basis for prevention and treatment of PCOS based on gut microbiota.

Cervical cancer (CC) poses a substantial global health challenge and it ranks as the fourth most prevalent malignancy among women worldwide. Management strategies include surgical intervention, radiotherapy, chemotherapy and emerging systemic treatments. Although advancements in immunotherapy and targeted therapies have been achieved, the aggressive metastatic nature of the disease, coupled with immune evasion and drug resistance, continues to limit overall survival rates. Therefore, there remains an urgent need to identify novel treatment modalities and more effective therapeutic agents. As fundamental regulators of epigenetic modifications, histone alterations serve a critical role in controlling gene expression, DNA repair mechanisms and cellular differentiation. These modifications include acetylation, methylation, phosphorylation, ubiquitination, ADP-ribosylation and glycosylation, as well as the more recently identified lactylation and palmitoylation. By restructuring chromatin and facilitating interactions among histones, DNA and regulatory proteins, these modifications exert a substantial influence on cellular functions. Aberrant histone modifications contribute to tumorigenesis, tumor heterogeneity and resistance to conventional anticancer therapies, making them a key focus of oncological research. In recent years, therapeutic strategies targeting histone modifications have gained increasing attention in the treatment of CC. Among these epigenetic alterations, histone acetylation and deacetylation have been extensively studied, with numerous histone deacetylase inhibitors showing promise in preclinical studies. The present review explores the patterns of histone modifications in CC, emphasizing their molecular roles in tumor progression, metastasis and therapeutic resistance. Additionally, histone modification-driven therapeutic targets are examined, laying the groundwork for future precision medicine approaches in CC treatment.

Endometritis is one of the common reproductive diseases in human and animal. In recent years, a number of studies have found that Schisandra B (Sch B), as a natural Chinese medicine extract, has antioxidant, anti‐inflammatory and other biological activities. Based on the above, in this study, mice were used to conduct an in vivo experiment to investigate the effect and mechanism of Sch B on lipopolysaccharide (LPS)‐induced endometritis. Haematoxylin and eosin (H&E) staining was used to detect the pathological changes of uterine tissue and western blot was used to detect the expression levels of signalling pathways and key genes for ferroptosis. The results showed that Sch B significantly inhibited the pathological injury of uterine tissue, myeloperoxidase (MPO) activity, the activation of NF‐κB pathway and the production of TNF‐α and IL‐1β. Furthermore, Sch B effectively inhibited ferroptosis by inhibiting malondialdehyde (MDA) and iron production and promoting the expression of ferroptosis suppressor genes GPX4 and ferritin. In conclusion, Sch B inhibited LPS‐induced endometritis through alleviating inflammatory response and ferroptosis via AMPK/PGC1α/Nrf2 signalling pathway.

Bacterial vaginosis (BV) is a common gynecological disease characterized by an abnormal increase in vaginal secretions, odor and itching. The pathogenesis of BV is not fully understood, but it is believed that the disruption of the mucosal immune system plays a key role. We investigated the role of IL-33 in preventing BV and explored the mechanism by which IL-33 regulates intravaginal IgA. Protein levels of IL-33 and IgA, and the pH value of vaginal secretions in healthy donors and patients with BV (14 vs 14) were determined by ELISA. -induced bacterial vaginosis mouse model was established using wild-type (WT) and IL-33 knockout (KO) mice. Protein levels of IL-33, IgA and TGF-β, the pH value of vaginal secretions, and Gram-staining were measured in vivo and in vitro to investigate the role of IL-33 in BV progression. IL-33 and IgA were significantly decreased in vaginal secretions of patients with BV. IL-33 deficiency aggravated BV induced by in a mouse model, while IL-33 supplementation prevented it. IL-33 modulated intravaginal IgA expression through the TGF-β signaling pathway in B cells. IL-33 prevents -induced BV by modulating intravaginal IgA expression through the TGF-β signaling pathway in B cells.

Unconventional oil and gas, represented by shale gas and shale oil, have occupied an important position in global energy. The rapid growth of shale gas and shale oil production shows great potential for the exploration and development of shale resources. Junggar basin, the main oil-bearing basin in China, is rich in oil and gas resources, so it is of great practical significance to carry out systematic research on the geological characteristics of shale reservoirs in this region. To this end, this paper designates the shale reservoir of Pingdiquan Formation in Huoshaoshan area of the Jungar Basin as the research object, carries out a geological survey in that area, analyzes reservoir forming conditions using the geological interpretation method, analyzes different local trap reservoir types and their main control factors by dissecting the explored reservoir, optimizes and evaluates favorable traps using the source, fault, facies and circle coupling analysis method, establishes single good identification standard of sedimentary microfacies, and carries out well-connected sedimentary microfacies analysis. Using geochemical methods, such as rock pyrolysis, maceral analysis, vitrinite reflectance, kerogen carbon isotope, saturated hydrocarbon chromatography, etc., the abundance and types of organic matter of shale in different intervals are analyzed and the geological characteristics of shale reservoirs are evaluated. This paper aims to analyze the oil and gas content of the shale reservoir in Pingdiquan Formation in the Junggar Basin to provide reliable reservoir evaluation and guide better development of shale oil and gas resources in the future. The innovative expenditure of this paper lies in conducting the research from two aspects: the analysis of the main controlling factors of reservoir formation from the structural point of view and the analysis of the pore structure and geochemical characteristics of shale from the core experiment point of view, and also the classification of organic matter, so as to provide a basis for finding favorable traps. The results show that the shale sedimentary system in the study area is a small fluvial delta, which belongs to a compression structure, with developed NNE-oriented structural belts and faults; the structural form is a short-axis anticline as a whole, forming a structural coil closure at −900 m, with a trap area of 50 km2 and a closure height of 180 m. According to the geological interpretation method, 19 faults of all levels were found in the area and the vertical migration conditions of oil and gas were good. Pingdiquan Formation was oil-bearing, with many vertical oil-bearing strata and strong horizontal independence of the reservoir. The sedimentary thickness of the Permian Pingdiquan Formation in the study area is 300~1200 m and the oil-bearing strata are divided into 3 oil-bearing formations, 9 sublayers, and 22 monolayers from top to bottom. The abundance of organic matter in different strata is generally high, with an average total organic carbon content of 3.53%, an average hydrocarbon generation potential of 18.1 mg/g, an average chloroform asphalt content of 0.57%, and an average total hydrocarbon content of 3011 μg/g, all of which belong to the shale standard, especially Ping-2. The organic matter in different layers belongs to types I-II1, and the organic matter types are I-II1, I-II2, and II1-II2, respectively. The average carbon isotope of shale kerogen is −2.4%, which belongs to type II2 kerogen.