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Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age
Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age
by Melendez Baez, Ivan , McPhee, Roderick , Yildirim, Inci in 2019-nCoV Vaccine mRNA-1273 - adverse effects , 2019-nCoV Vaccine mRNA-1273 - immunology , 2019-nCoV Vaccine mRNA-1273 - therapeutic use
2022
In part 1 of a phase 2–3 trial, a 50-μg dose of mRNA-1273 vaccine was safe and immunogenic. In part 2, nearly 4000 6-to-11-year-olds received two doses of vaccine or placebo and were followed for a median of 82 days. The vaccine had mainly mild adverse effects and was immunogenic in 99%, similar to the results in 18-to-25-year-olds. Vaccine efficacy during a delta-variant period was 88%.
Journal Article
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