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"ZHANG XiaoShuang LIU Yan ZHAO Li LI Bing YU Hao WEN HongLing YU Xue-Jie"
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An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV
by
ZHANG XiaoShuang LIU Yan ZHAO Li LI Bing YU Hao WEN HongLing YU Xue-Jie
in
Alanine transaminase
,
Animals
,
Arachnid Vectors - virology
2013
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in rural areas of China and is caused by a new bunyavirus, SFTSV, named after the disease. The transmission vectors and animal hosts of SFTSV are unclear. Ticks are the most likely transmission vectors and domestic animals, including goats, dogs, and cattle, are potential amplifying hosts of SFTSV. The clinical symptoms of SFTS are nonspecific, but major symptoms include fever, gastrointestinal symptoms, myalgia, dizziness, joint pain, chills, and regional lymphadenopathy. The most common abnormalities in laboratory test results are thrombocytopenia (95%), leukocytopenia (86%), and elevated levels of serum alanine aminotransferase, aspartate ami- notransferase, creatine kinase, and lactate dehydrogenase. The fatality rate for SFTS is 12% on average, and the annual inci- dence of the disease is approximately five per 100000 of the rural population.
Journal Article