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A bstract We present a measurement of the doubly radiative decay η → π 0 γγ based on a sample of 82 million η mesons produced in the e + e − → ϕ → ηγ process at the Frascati ϕ -factory DAΦNE. From the data analysis, 1246 ± 133 signal events were observed. By normalising the signal to the well-known η → 3 π 0 decay the branching fraction is measured to be (0 . 98 ± 0 . 11 stat ± 0 . 14 syst ) × 10 − 4 . This result agrees with a preliminary KLOE measurement, but is a factor of two smaller than the current world average. Results for d Γ( η → π 0 γγ ) /dM 2 ( γγ ) are also presented and compared with the latest theoretical predictions.

We present a measurement of the doubly radiative decay η → π0γγ based ona sample of 82 million η mesons produced in the e+e− → ϕ → ηγ process at the Frascatiϕ-factory DAΦNE. From the data analysis, 1246 ± 133 signal events were observed. Bynormalising the signal to the well-known η → 3π0 decay the branching fraction B(η → π0γγ) ismeasured to be (0.98 ± 0.11stat ± 0.14syst) × 10−4. This result agrees with a preliminary KLOEmeasurement, but is a factor of two smaller than the current world average. Results for dΓ(η →π0γγ)/dM 2(γγ) are also presented and compared with the latest theoretical predictions.

This study was aimed to determine the ideal thresholds for bone mineral densities in our tested Jordanian cohort to initiate bisphosphonate pharmacotherapeutics in order to establish a national protocol for prescribing bisphosphonates that is tailored to the local population, rather than relying on global T and Z scores standards. This retrospective study analyzed the entire population of adult patients at Prince Rashid bin Al-Hussein Hospital Rehabilitation and Rheumatology Center between August and October 2023 for the purpose of screening, monitoring, diagnosing, and treating osteoporosis. The study included 328 clients suspected to have osteoporosis, selected based on criteria such as primary osteoporosis or potential secondary osteoporosis. The study used two fracture risk assessment tools (FRAX) dichotomized states: <3% (negative state) and ≥3% (positive state), as well as <20% (negative state) and ≥20% (positive state). Binary logistic regression analysis, receiver-operating characteristic, and sensitivity analysis tests were performed sequentially to analyze the performance of prognosticators and sensitivity indices to evaluate their sensitivity, specificity, and accuracy indexes. The study involved 328 clients at a rehabilitation clinic, with 82.62% (271) females and 17.38% (57) males. The majority were aged between 60 and 69 years, with a slightly higher obesity rate in females. The study found that initiation of bisphosphonates in Jordanian cohorts with optimal bone mineral density thresholds of 0.775 g/cm may significantly reduce the risk of hip osteoporosis over 10 years, with sensitivity, specificity, and accuracy indexes of 78.6%, 88.46%, and 50.61%, respectively, with a performance utility of 0.896±0.026 (p-value<0.001), 95% CI (0.846-0.946). Due to ethnicity differences, exploring regional or national specific bone mineral density thresholds for bisphosphonates initiation may be a better optional choice than adopting global T-score standards.

AimsIn the placebo-controlled, double-blind BOne marrOw transfer to enhance ST-elevation infarct regeneration (BOOST) 2 trial, intracoronary autologous bone marrow cell (BMC) transfer did not improve recovery of left ventricular ejection fraction (LVEF) at 6 months in patients with ST-elevation myocardial infarction (STEMI) and moderately reduced LVEF. Regional myocardial perfusion as determined by adenosine stress perfusion cardiac magnetic resonance imaging (S-CMR) may be more sensitive than global LVEF in detecting BMC treatment effects. Here, we sought to evaluate (i) the changes of myocardial perfusion in the infarct area over time (ii) the effects of BMC therapy on infarct perfusion, and (iii) the relation of infarct perfusion to LVEF recovery at 6 months.Methods and resultsIn 51 patients from BOOST-2 (placebo, n = 10; BMC, n = 41), S-CMR was performed 5.1 ± 2.9 days after PCI (before placebo/BMC treatment) and after 6 months. Infarct perfusion improved from baseline to 6 months in the overall patient cohort as reflected by the semi-quantitative parameters, perfusion defect–infarct size ratio (change from 0.54 ± 0.20 to 0.43 ± 0.22; P = 0.006) and perfusion defect–upslope ratio (0.54 ± 0.23 to 0.68 ± 0.22; P < 0.001), irrespective of randomised treatment. Perfusion defect–upslope ratio at baseline correlated with LVEF recovery (r = 0.62; P < 0.001) after 6 months, with a threshold of 0.54 providing the best sensitivity (79%) and specificity (74%) (area under the curve, 0.79; 95% confidence interval, 0.67–0.92).ConclusionInfarct perfusion improves from baseline to 6 months and predicts LVEF recovery in STEMI patients undergoing early PCI. Intracoronary BMC therapy did not enhance infarct perfusion in the BOOST-2 trial.Graphic abstract

Volatiles from aqueous extract of peppermint commercial sachets were investigated through gas chromatography/flame ionization detection (GC/FID) and GC/mass spectrometry (MS). Samples were prepared under similar conditions as in homemade tea. Volatiles were isolated using solid phase extraction method (SPE) with Porapak Q trap followed by desorption with acetone. Estimated mean values for short and medium chain carboxylic acids (C2-C12) and ketones lay in the range of 50-64 microg kg(-1) whilst aliphatic alcohols and acyclic hydrocarbons had values lower than 6 microg kg(-1). The major volatiles were terpenes (275-382 microg kg(-1)) that reached 89 % of the total composition. A total of 16 compounds, among them dodecane, acetoin, acetol, citral, geraniol and octanoic acid have been described by the first time in peppermint tea. These findings could be attributed to the different analytical approach employed, mainly to the use of different extraction/pre-concentration techniques. Given the apparently lower proportion of terpenes in the aqueous extract it may be that the chemical properties of the peppermint essential oil are not entirely reproduced with homemade tea.

The date palm, Phoenix dactylifera L. is the notable palm which produces a nutrient-rich edible fruit (the date), well known for its unique attributes of medicine and healthy energy. It is a species that has been cultivated since early civilizations in the fertile crescent and later in the Middle East. It is typically cloned with many cultivars (over 3000). A means of accurately identifying specific clones and an understanding of the relationships among major commercial cultivars would provide valuable information for the maintenance, potentially an improvement and continued conservation of superior genotypes. Phylogenetic relationships amid commercial date cultivars are poorly understood, despite their importance. This research aimed at providing applicable knowledge through an expedient technique, by developing an exclusively tailored Simple Sequence Repeat (SSR) panel, custom-made for date palm fingerprinting and molecular identification also named as ‘Dates PalmàPrinting’. This assembled modified genotyping by microsatellite markers provides a standardized approach to cultivar identification and a quality control application in date palm micropropagation production. A deeper understanding and relationship of today’s major commercial cultivars is incomplete. Improving the development and productivity of this tree species is restricted due to few genetic resources. Only regionally narrowed studies have been conducted but it is more important to have a broader base of such knowledge.The present research reports on 20 selected, commercially important date palm cultivars, consisting of 18 females and 2 males, which are grown throughout the world. The knowledge of relationships among these cultivars is needed, although the date palm genome has been mostly sequenced (90.2 %) with 41,660 gene models representing an 82,354 scaffold. The relationships among the major cultivars remain unclear. Presently, the information on the characterization of these cultivars requires an assessment to better understand the relationships among the superior genotypes. The use of microsatellites, due to their accuracy and high polymorphic capability, have led to fine scaled phylogenies. The phylogenetic relationships were determined using neighbor joining un-rooted trees correlated with genetic structure clustering. Primer selections were achieved from evaluation of 14 nuclear SSR loci isolated from P. dactylifera. Results revealed a high degree of polymorphism observed in the 20 cultivars with fewer common alleles than anticipated. Within the cultivars studied, a broad heterozygosity across base pair (bp) amplification data has led to an understanding of limited inbreeding, accounting for possible adaptation to environmental changes and revealing conserved extensive array of genomic structure. Population structure analysis suggests a large genetic boundary between Northwest African and Middle Eastern cultivars with 6 subpopulations that represent divergences and fragments of admixture in cultivars present in these regions. The possible selection of potential and good quality parents is achievable for improving cultivars by generating population and structure maps. This analysis documents patterns of relationship and provides genetic structure and diversity of gene pool specificity complexes of date palm cultivars.This study provides insights about the relationships that exist among cultivars of interest through genetic sequence analysis using SSRs, facilitating the development of a standard approach to identification and enhancements to the micropropagation process.

When subjected, directly (through nutritional deficiencies) or indirectly (through alkaline constraints leading to such deficiencies) to nutrient deficiencies, certain plants respond by developing special root structures called cluster roots. This phenomenon can be considered as an ecophysiological response to a specific nutrient deficiency enabling plants to enhance nutrient uptake. Experiments conducted on an alkaline and an acid soil showed that Casuarina glauca (Sieber ex Spreng.) produced cluster roots only in the alkaline soil and not in the acid soil. In addition, iron (Fe) and phosphorus (P) deficiencies were examined separately or together to determine their effect on cluster root formation in C. glauca seedlings grown hydroponically. Results from experiments carried out on three Casuarina species (C. glauca, C. cunninghamiana Miq. and C. equisetifolia L.) indicated that Fe is involved in cluster root formation. In nutrient media lacking P but containing Fe, no cluster roots formed while seedlings receiving P and lacking Fe developed cluster roots. When incubated on chrome-azurol S-agar on blue plates (CAS assay), a technique used routinely to detect the production of siderophores by micro-organisms, the root system of Fe-deficient plants exhibited orange halos around cluster roots, indicating production of a ferric-chelating agent. It is concluded that the capacity of cluster roots of C. glauca to chelate Fe allows the plant to grow normally on alkaline soils.

We present a measurement of the radiative decay \\(^0\\) using 82 million \\(\\) mesons produced in \\(e^+e^-\\) process at the Frascati \\(\\)-factory DA\\(\\)NE. From the data analysis \\(1246133\\) signal events are observed. By normalising the signal to the well-known \\(3^0\\) decay the branching fraction \\( B(^0)\\) is measured to be \\((0.98 0.11_stat 0.14_syst)10^-4\\). This result agrees with a preliminary KLOE measurement, but is twice smaller than the present world average. Results for \\(d(^0)/dM^2()\\) are also presented and compared with latest theory predictions.