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Food businesses, such as food trucks (FTs) and family producers have grown rapidly and become popular with people in Saudi Arabia. As foodborne diseases are still a public health concern in the country, consumers should be aware of the safety of foods sold by food trucks. Since there is a dearth of literature, this study aimed to assess the knowledge and attitudes of consumers of food from FTs owned by family producers regarding food safety and foodborne disease. A cross-sectional study was conducted among 921 consumers of food from FTs from two cities in the southern region of Saudi Arabia. Data were collected using an online questionnaire from September to November 2021. Finally, multiple linear regression and a logistic regression model were used to identify the predictors of knowledge and attitude regarding food safety and foodborne illness, respectively. Overall, respondents had moderate knowledge and higher positive attitudes regarding food safety and foodborne illness. Respondents’ knowledge about the potential harm and attitudes towards the safety of foods sold by FTs were significantly associated with marital status, education level, and monthly family income. The findings of this study highlight the need to improve the knowledge, awareness, and attitudes of Saudi consumers of food from FTs owned by family producers on food safety and foodborne illness through intervention programs, particularly targeting consumers with lower educational attainments and income status, to control foodborne diseases.

Background Globally, febrile convulsions (FC) constitute a respected prevalence scale among pediatric population. This usually induces a high parental anxiety. Aim To investigate the local community diversity of perception as regards FC. Method A cross-sectional anonymous Arabic questionnaire-based study took place targeting the Saudi community. The study included parents with at least a child who underwent FC. Excluded, were those who have children with convulsions due to other causes rather than FC. Results Eight hundred participants have fulfilled the study inclusion criteria. Majority of them (84%) were mothers. While 10.9% had only one child diagnosed with FC. Participants believed that FC may induce brain damage (41.4%). Others expressed FC attacks to be life-threatening events (52.9%). They were convinced that FC is not related to epilepsy (40.2%). However, a respected percentage of participants denoted the importance of using oral protective devices during the attacks (41.4%). Overall, most study population (84%) had poor perception of the different aspects of FC. Conclusion Social perception of FC problems may be significantly related to the educational level and profession of the parents. The majority of the study subjects have poor perception as regards FC. Therefore, holistic socially oriented educational programs are needed to orient the population about the problem. They may be implemented via various approaches.

Background Breast cancer remains one of the leading causes of cancer-related mortality among women worldwide, with more than 2.3 million new cases and approximately 670,000 deaths reported globally in 2022. Early and accurate diagnosis significantly improves survival rates; however, conventional diagnostic approaches are often time-consuming and subject to inter-observer variability. Although machine learning techniques have demonstrated promising results, many existing studies lack systematic hyperparameter optimization and robust strategies to improve model generalization. This study aimed to develop an optimized and interpretable K-Nearest Neighbour (KNN) framework for breast cancer classification. Methods The Breast Cancer Wisconsin (Diagnostic) Dataset (WDBC), comprising 569 samples with 32 features, was used for model development and evaluation. The proposed framework incorporated advanced preprocessing, biologically informed feature engineering, hybrid feature selection, and systematic hyperparameter tuning using GridSearchCV. An ensemble KNN model employing soft voting was introduced to enhance predictive stability and performance. Model interpretability was improved using the Local Interpretable Model-Agnostic Explanations (LIME) technique to identify feature contributions for malignant and benign classifications. Results The optimized KNN model achieved an accuracy of 98.25%, while the ensemble KNN model reached 99.12% accuracy. The proposed framework demonstrated high predictive performance, improved classification stability, and enhanced interpretability through feature-level explanation analysis. Conclusions The findings demonstrate the methodological effectiveness of an optimized and ensemble-based KNN framework for breast cancer classification. While the results indicate strong benchmark performance on the WDBC dataset, the study primarily highlights methodological robustness rather than immediate clinical generalizability. Further validation on multi-center clinical datasets is required before practical deployment in decision-support systems.

Background Blunt abdominal trauma is a prevailing cause of pediatric morbidity and mortality. It constitutes the most frequent type of pediatric injuries. Contrast-enhanced sonography (CEUS) and contrast-enhanced computed tomography (CECT) are considered pivotal diagnostic modalities in hemodynamically stable patients. Aim To report the experience in management of pediatric split liver and spleen injuries using CEUS and CECT. Patients and methods This study included 246 children who sustained blunt abdominal trauma, and admitted and treated at three tertiary hospitals in the period of 5 years. Primary resuscitation was offered to all children based on the advanced trauma and life support (ATLS) protocol. A special algorithm for decision-making was followed. It incorporated the FAST, baseline ultrasound (US), CEUS, and CECT. Patients were treated according to the imaging findings and hemodynamic stability. Results All 246 children who sustained a blunt abdominal were studied. Patients' age was 10.5 ± 2.1. Road traffic accidents were the most common cause of trauma; 155 patients (63%). CECT showed the extent of injury in 153 patients’ spleen (62%) and 78 patients’ liver (32%), while the remaining 15 (6%) patients had both injuries. CEUS detected 142 (57.7%) spleen injury, and 67 (27.2%) liver injury. Conclusions CEUS may be a useful diagnostic tool among hemodynamically stable children who sustained low-to-moderate energy isolated blunt abdominal trauma. It may be also helpful for further evaluation of uncertain CECT findings and follow-up of conservatively managed traumatic injuries.

(1) Background: Functional habitual constipation (FC) in children is a common gastrointestinal problem. This study aimed to explore the local community’s view on this problem, emphasising the challenges that parents face in managing the condition and its impact on the child’s quality of life. (2) Methods: A prospective, cross-sectional, community-based study was conducted between March and July 2023. The survey received 933 responses. The target population was adults over 18 years of age living in the Eastern Province of Saudi Arabia. An electronically distributed questionnaire was designed in the Arabic language. (3) Results: The mean knowledge scores were significantly higher in females than males, with t (931) = −2.701 and p = 0.007. The Bonferroni post hoc test results indicated that participants between 20 and 29 years exhibited significantly higher levels of knowledge scores compared to those between 30 and 39 years. Furthermore, the results revealed that those with three or more children had significantly higher knowledge scores compared to those with only one child. (4) Conclusions: This study demonstrated that parents in the local community have a good perceived knowledge of FC, but it needs to be linked with practice. They tended to report high levels of perception and demonstrated better practices. These results emphasise the importance of exploring the local community’s view on constipation among children.

BackgroundThyroid nodules are an important health problem in children and adolescents. They possess a higher risk of malignancy in comparison to adults. This fact forms a great dilemma for clinicians. The aim of this study was to evaluate the reliability of shear wave elastography (SWE) as a non-invasive technique in the characterization of thyroid nodules in children and adolescents.MethodsThis prospective study included 56 patients with thyroid nodules. All the patients underwent clinical assessment, laboratory investigations, ultrasound, and Doppler examination, followed by an SWE assessment. Statistical analysis was performed and the best cut-off value to differentiate benign from malignant nodules was determined using the ROC curve and AUC.ResultsSeventy-two nodules were detected in the examined patients (ages ranged from 11 to 19 years, with mean age of 14.89 ± 2.3 years). Fifty-eight nodules (80.6%) were benign, and fourteen nodules (19.4%) were malignant (histopathologically proved). Highly suspicious criteria for prediction of malignancy by ultrasound and Doppler were hypoechoic echopattern, internal or internal and peripheral vascularity, microcalcifications, taller-than-wide dimensions, irregular outlines, and absence of halo (p < 0.05). The diagnostic performance for their summation was 70.69% sensitivity, 82.8% specificity, 80.45% accuracy, a 63.79% positive predictive value (PPV), and 87.9% negative predictive values (NPV). Regarding SWE, our results showed that 42.2 kPa was the best cut-off value, with AUC = 0.921 to differentiate malignant from benign nodules; the diagnostic performance was 85.71% sensitivity, 94.83% specificity, 93.06% accuracy, 76.9% PPV, and 93.2% NPV.ConclusionShear wave elastography is a non-invasive technique that can assist in the diagnosis of malignant thyroid nodules among children and adolescents.

We aimed to evaluate the outcome of different treatment modalities for extremity venous thrombosis (VT) in neonates and infants, highlighting the current debate on their best tool of management. This retrospective study took place over a 9-year period from January 2009 to December 2017. All treated patients were referred to the vascular and pediatric surgery departments from the neonatal intensive care unit. All patients underwent a thorough history-taking as well as general clinical and local examination of the affected limb. Patients were divided into 2 groups: group I included those who underwent a conservative treated with the sole administration of unfractionated heparin (UFH), whereas group II included those who were treated with UFH plus warfarin. Sixty-three patients were included in this study. They were 36 males and 27 females. Their age ranged from 3 to 302 days. Forty-one (65%) patients had VT in the upper limb, whereas the remaining 22 (35%) had lower extremity VT. The success rate of the nonsurgical treatment was accomplished in 81% of patients. The remaining 19% underwent limb severing, due to established gangrene. The Kaplan-Meier survival method revealed a highly significant increase in both mean and median survival times in those groups treated with heparin and warfarin compared to heparin-only group (P < .001). Nonoperative treatment with anticoagulation or observation (ie, wait-and-see policy) alone may be an easily applicable, effective, and a safe modality for management of VT in neonates and infants, especially in developing countries with poor or highly challenged resource settings.

Background and Objectives: On a local and national scale, genitourinary malformations (GUMs) are the second most encountered congenital anomaly in children. GUMs are linked to several risk factors, including maternal co-morbidities and insufficient folic acid. They may also be related to maternal health and care during pregnancy. Expanding our knowledge about these factors is necessary for the development of preventative measures, which could reduce GUM incidence. This study evaluated the local youth’s understanding and perceptions of genitourinary anomalies. Materials and Methods: This cross-sectional, qualitative, anonymous, questionnaire-based study involved members of the local population, aged 18 years or over. Based on a 5% type I error rate (α = 0.05) and an 80% response rate, a sample size of 481 was determined. The questionnaire was completed by 902 people. The data were analyzed using SPSS version 25 (IBM). Results: Over half (57%) of respondents believed that hormonal therapy during pregnancy could increase GUM risk. Moreover, 46% thought that maternal chronic diseases could be another risk factor, while 43% believed that pregnancy-related conditions, such as pre-eclampsia, increased GUM risk. Women had higher odds of high perception scores than men, according to the univariate and multivariate analyses. Most participants (74%) strongly agreed that proper and ongoing prenatal follow-ups are necessary, 69% agreed that premarital medical check-ups are necessary, and 67% believed that optimal nutrition throughout pregnancy is necessary to reduce GUM risk. Conclusions: The results emphasize the necessity of developing healthcare strategies specifically designed to increase knowledge about GUMs and overcome incorrect community perceptions of risk factors that could also help improve attitudes towards prevention and ultimately reduce the incidence of GUMs.

Background Choosing a medical specialty poses a significant challenge for students, with initial fascinations often evolving during their academic journey. Despite its inherent appeal, neurosurgery faces hesitancy among undergraduate students, potentially due to perceived difficulties and time demands. This study aims to investigate the factors influencing medical students' intentions toward neurosurgery at two institutions in the eastern province of Saudi Arabia. Methodology A cross-sectional study design was employed, utilizing a validated, anonymous questionnaire distributed electronically to medical students and interns in the eastern province of Saudi Arabia. The questionnaire comprised two sections, namely, demographic and academic profiles, and participants' intentions, knowledge, and attitudes toward neurosurgery. Data analysis involved descriptive statistics, and chi-square tests to explore relationships and identify significant predictors. Results Of the participants, 197 (34.1%) expressed interest in neurosurgery, but only 94 (16.3%) had a comprehensive understanding of the field. Motivations included high income, specialty prestige, and positive impact on patients, while stress and work-life balance were common deterring factors. Age and academic years were associated with a gradual decrease in interest, except for initial medical school students. Participants were attracted to innovative technological aspects, while high competition and neurophobia were deterring factors. Conclusions This study provides a comprehensive analysis of determinants influencing medical students' and interns' interest in neurosurgery. Early exposure, clinical training, and personal motivations play significant roles in shaping career preferences. Challenges, such as perceived difficulties and concerns related to work-life balance, need targeted interventions to enhance neurosurgery's attractiveness. Considerations extend beyond technical and academic facets to encompass personal and lifestyle dimensions.

Sickle cell disease (SCD) is among the prevalent chronic diseases in the Eastern Province of Saudi Arabia. To our knowledge, there is no published research that reports the reasons for hospitalization in the Eastern Province of the country. Therefore, this study aimed to fill this gap. This is a retrospective cohort study that was conducted in the period from January 2018 to December 2019. Patients with sickle cell disease who were admitted and treated in the hospital were included in this study. Patients' sociodemographic data and reasons for hospitalization were collected and analyzed using the statistical package for social sciences, version 21 (SPSS, Chicago, IL, USA). There were 103 SCD patients, and the age range was from 18 to 62 years old. The majority of the patients were males (56.3%) and were in the younger age group (≤30 years old; 60.2%). The results showed that the most frequent cause of admission was a vaso-occlusive crisis (VOC) (n=94, 91.3%), followed by acute chest syndrome (ACS) (n=32, 31.1%), and then by hemolytic crisis (27 of the cases; 26.2%). However, we found that a higher number of hip avascular necrosis (AVN) cases were statistically significant in relation to the higher number of hospital admissions (p<0.05), whereas other reasons were not found to have a statistically significant association. The most frequent cause of admission was VOC episodes, followed by ACS, and then by hemolytic crises. Also, a higher number of hip AVN episodes were statistically significant with the higher number of hospital admissions.