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The precision of agro-technical operations is one of the main hallmarks of a modern approach to agriculture. However, ensuring the precise application of plant protection products or the performance of mechanical field operations entails significant costs for sophisticated positioning systems. This paper explores the integration of precision positioning based on the global navigation satellite system (GNSS) in agriculture, particularly in fieldwork operations, seeking solutions of moderate cost with sufficient precision. This study examines the impact of GNSSs on automation and robotisation in agriculture, with a focus on intelligent agricultural guidance. It also discusses commercial devices that enable the automatic guidance of self-propelled machinery and the benefits that they provide. This paper investigates GNSS-based precision localisation devices under real field conditions. A comparison of commercial and low-cost GNSS solutions, along with the integration of satellite navigation with advanced visual odometry for improved positioning accuracy, is presented. The research demonstrates that affordable solutions based on the common differential GNSS infrastructure can be applied for accurate localisation under real field conditions. It also underscores the potential of GNSS-based automation and robotisation in transforming agriculture into a more efficient and sustainable industry.

Baler-wrappers are machines designed to produce high-quality forage, in accordance with the requirements of sustainable agriculture. Their complicated structure, and significant loads occurring during operation, prompted the creation of systems for controlling the machines’ processes and measuring the most important work parameters, in this work. The compaction control system is based on a signal from the force sensors. It allows for detection differences in the compression of the bale and additionally protects against overload. The method of measuring the swath size, with the use of a 3D camera, was presented. Scanning the surface and travelled distance allows for estimating the volume of the collected material—making it possible to create yield maps (precision farming). It is also used to vary the dosage of ensilage agents, that control the fodder formation process, in relation to the moisture and temperature of the material. The paper also deals with the issue of measuring the weight of the bales—securing the machine against overload and collecting data for planning the bales’ transport. The machine, equipped with the above-mentioned systems, allows for safer and more efficient work, and provides information about the state of the crop in relation to a geographical position, which allows for further inferences.

Despite clear technical superiority of genome sequencing (GS) over other diagnostic methods such as exome sequencing (ES), few studies are available regarding the advantages of its clinical application. We analyzed 1007 consecutive index cases for whom GS was performed in a diagnostic setting over a 2-year period. We reported pathogenic and likely pathogenic (P/LP) variants that explain the patients’ phenotype in 212 of the 1007 cases (21.1%). In 245 additional cases (24.3%), a variant of unknown significance (VUS) related to the phenotype was reported. We especially investigated patients which had had ES with no genetic diagnosis (n = 358). For this group, GS diagnostic yield was 14.5% (52 patients with P/LP out of 358). GS should be especially indicated for ES-negative cases since up to 29.6% of them could benefit from GS testing (14.5% with P/LP, n = 52 and 15.1% with VUS, n = 54). Genetic diagnoses in most of the ES-negative/GS-positive cases were determined by technical superiority of GS, i.e., access to noncoding regions and more uniform coverage. Importantly, we reported 79 noncoding variants, of which, 41 variants were classified as P/LP. Interpretation of noncoding variants remains challenging, and in many cases, complementary methods based on direct enzyme assessment, biomarker testing and RNA analysis are needed for variant classification and diagnosis. We present the largest cohort of patients with GS performed in a clinical setting to date. The results of this study should direct the decision for GS as standard second-line, or even first-line stand-alone test.

This article presents a division of methods to support mechanical weeding based on mechatronic control systems and estimates their effectiveness. The subject was undertaken due to the noticeable increase in interest in machine weeding methods, which is the result of the need for farmers to meet the growing awareness of customers focusing on healthy and high-quality products and the European Union policy promoting environmental protection programs, such as the European Green Deal and supporting commission priorities like the Mission Soil as a flagship initiative of the long-term vision for the EU’s rural areas. Mechanical weeding meets the stringent conditions set by organic farming, and automation favours the development of these methods. Based on sources in the literature, it has been shown that it is possible to increase the weeding speed by at least 1.6 times by using the tool position correction system for row crops. In the case of crops requiring weeding, and in the spaces between plants in a row, the use of specialised weeding machines allows for an increase in the weeding efficiency by up to 2.57 times compared to manual weeding. Each of the analysed methods used to support weeding are subject to a certain error due to the use of sources in the literature, including manufacturers’ materials; however, it shows an upward trend in the effectiveness of using mechatronic weeding support systems, which was part of the thesis. This article presents the division of these systems and analyses the specific market solutions of machines, which is its distinguishing feature.

We report a stability below 7 × 10 −17 of two independent optical lattice clocks operating with bosonic 88 Sr isotope. The value (429 228 066 418 008.3(1.9) syst (0.9) stat Hz) of the absolute frequency of the 1 S 0  –  3 P 0 transition was measured with an optical frequency comb referenced to the local representation of the UTC by the 330 km-long stabilized fibre optical link. The result was verified by series of measurements on two independent optical lattice clocks and agrees with recommendation of Bureau International des Poids et Mesures.

The AEg̅IS collaboration at CERN’s AD produces antihydrogen atoms in the form of a pulsed, isotropic source with a precisely defined formation time. AEg̅IS has recently undergone major upgrades to fully benefit from the increased number of colder antiprotons provided by the new ELENA decelerator and to move toward forming a horizontal beam to directly investigate the influence of gravity on the H̅ atoms, thereby probing the Weak Equivalence Principle for antimatter. This contribution gives an overview of these upgrades as well as subsequent results from the first beam times with ELENA.

The progressive technical development of agriculture and the desire to increase the efficiency and quality of agrotechnical processes related to soil cultivation forces the use of more and more complex automation and robotisation processes in agricultural technology. The article introduces the reader to modern control systems for automatic hoeing tools and presents a modern control system for a baler-wrapper, the project of which (POIR.04.01.04-00-0067/18) is implemented by the authors in the Łukasiewicz Research Network Industrial Institute of Agricultural Engineering consortium with the Metal-Fach company. One of the reasons for the automatisation of agricultural machinery is the departure from chemical methods of cultivating crops, due to the growing awareness of consumers who want ecological and thus healthier products. The influence of automation on organic farming was characterized and its general principles were presented. The automatic cultivators were divided based on the kinematics of the tool movements they operate on the basis of machine vision. The results of the baler-wrapper tests were presented, confirming the validity of the designed control system. The authors summarized the main advantages and disadvantages of the systems for correcting the position of working tools of machines, considering the profitability of this type of investment on the example of weeder and a baler-wrapper. The article adopts the hypothesis that the development of agricultural automation has a positive effect on the development and popularity of organic farming.

A powerful and robust control system is a crucial, often neglected, pillar of any modern, complex physics experiment that requires the management of a multitude of different devices and their precise time synchronisation. The AEgIS collaboration presents CIRCUS, a novel, autonomous control system optimised for time-critical experiments such as those at CERN's Antiproton Decelerator and, more broadly, in atomic and quantum physics research. Its setup is based on Sinara/ARTIQ and TALOS, integrating the ALPACA analysis pipeline, the last two developed entirely in AEgIS. It is suitable for strict synchronicity requirements and repeatable, automated operation of experiments, culminating in autonomous parameter optimisation via feedback from real-time data analysis. CIRCUS has been successfully deployed and tested in AEgIS; being experiment-agnostic and released open-source, other experiments can leverage its capabilities.

NEXCERA has emerged as a ceramic-based material for spacers in ultra-stable optical cavities, with a coefficient of thermal expansion that crosses zero near room temperature. In such cavities, frequency stability is ultimately limited by Brownian thermal noise in the cavity components. A key parameter in this context is the mechanical loss, which has remained unknown for NEXCERA. In this work, we investigate the mechanical loss of NEXCERA N117B at room temperature for various resonances using the gentle nodal suspension technique. We measure a promising minimum mechanical loss of \\( = 1.89 10^-5\\), indicating the suitability of NEXCERA for low-noise optical cavities. Using this value, we calculate the thermal noise of a cavity with a NEXCERA spacer and compare its performance to established materials such as ULE and Zerodur, taking into account different mirror substrate options. Our analysis shows that NEXCERA is a strong candidate for ultra-stable cavities due to its low thermal noise. Combined with its previously reported low linear drift, it offers a highly attractive option for long-term stable optical frequency references.