Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
45,371
result(s) for
"Zhang, Fu"
Sort by:
Resequencing 545 ginkgo genomes across the world reveals the evolutionary history of the living fossil
As Charles Darwin anticipated, living fossils provide excellent opportunities to study evolutionary questions related to extinction, competition, and adaptation. Ginkgo (
Ginkgo biloba
L.) is one of the oldest living plants and a fascinating example of how people have saved a species from extinction and assisted its resurgence. By resequencing 545 genomes of ginkgo trees sampled from 51 populations across the world, we identify three refugia in China and detect multiple cycles of population expansion and reduction along with glacial admixture between relict populations in the southwestern and southern refugia. We demonstrate multiple anthropogenic introductions of ginkgo from eastern China into different continents. Further analyses reveal bioclimatic variables that have affected the geographic distribution of ginkgo and the role of natural selection in ginkgo’s adaptation and resilience. These investigations provide insights into the evolutionary history of ginkgo trees and valuable genomic resources for further addressing various questions involving living fossil species.
Ginkgo is one of the living fossils from the plant kingdom. Here, authors conduct population genomics analyses to reveal its refugia and demographic history, and provide evidence of multiple anthropogenic introductions of ginkgo from eastern China into different continents.
Journal Article
A history of Chinese theatre in the 20th century IV
The 20th century was a dynamic period for the theatrical arts in China. The four volumes of A History of Chinese Theatre in the 20th Century display the developmental trajectories of Chinese theatre over those hundred years. 0This volume examines the development of Chinese theatrical art from the Cultural Revolution to the end of the 20th century. The Cultural Revolution had a devastating influence on the theatrical profession, reducing the creation of performance art to serving the political authorities. Adopting a critical view, the author argues that the Reform and Opening-up of the late 1970s not only ended this period of political interference, but also brought about chaos and doubts to the theatrical circle, since neither tradition nor western concepts were a panacea for the problems faced by Chinese theatre. He posits that people should advocate patterns of drama that are rich and colourful in their expression while encouraging the coexistence and competition of different artistic concepts. Scholars and students in the history of the arts, especially the history of Chinese theatre, will find this book to be an essential guide. Vol. 1: 9780367462154; Vol.2: 9781138330665; Vol. 3: 9780367773953.
BOOK
Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center’s observational study
Background
An outbreak of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 was first detected in Wuhan, Hubei, China. People of all ages are susceptible to SARS-CoV-2 infection. No information on severe pediatric patients with COVID-19 has been reported. We aimed to describe the clinical features of severe pediatric patients with COVID-19.
Methods
We included eight severe or critically ill patients with COVID-19 who were treated at the Intensive Care Unit (ICU), Wuhan Children’s Hospital from January 24 to February 24. We collected information including demographic data, symptoms, imaging data, laboratory findings, treatments and clinical outcomes of the patients with severe COVID-19.
Results
The onset age of the eight patients ranged from 2 months to 15 years; six were boys. The most common symptoms were polypnea (8/8), followed by fever (6/8) and cough (6/8). Chest imaging showed multiple patch-like shadows in seven patients and ground-glass opacity in six. Laboratory findings revealed normal or increased whole blood counts (7/8), increased C-reactive protein, procalcitonin and lactate dehydrogenase (6/8), and abnormal liver function (4/8). Other findings included decreased CD16 + CD56 (4/8) and Th/Ts*(1/8), increased CD3 (2/8), CD4 (4/8) and CD8 (1/8), IL-6 (2/8), IL-10 (5/8) and IFN-γ (2/8). Treatment modalities were focused on symptomatic and respiratory support. Two critically ill patients underwent invasive mechanical ventilation. Up to February 24, 2020, three patients remained under treatment in ICU, the other five recovered and were discharged home.
Conclusions
In this series of severe pediatric patients in Wuhan, polypnea was the most common symptom, followed by fever and cough. Common imaging changes included multiple patch-like shadows and ground-glass opacity; and a cytokine storm was found in these patients, which appeared more serious in critically ill patients.
Journal Article
Two-stage superconductivity in the Hatsugai–Kohomoto-BCS model
Superconductivity in strongly correlated electrons can emerge out from a normal state that is beyond the Landau’s Fermi liquid paradigm, often dubbed as ‘non-Fermi liquid’. While the theory for non-Fermi liquid is still not yet conclusive, a recent study on the exactly-solvable Hatsugai–Kohomoto (HK) model has suggested a non-Fermi liquid ground state whose Green’s function resembles the Yang–Rice–Zhang ansatz for cuprates (2020 Phillips et al Nat. Phys. 16 1175). Similar to the effect of on-site Coulomb repulsion in the Hubbard model, the repulsive interaction in the HK model divides the momentum space into three parts: empty, single-occupied and double-occupied regions, that are separated from each other by two distinct Fermi surfaces. In the presence of an additional Bardeen–Cooper–Schrieffer-type pairing interaction of a moderate strength, we show that the system exhibits a ‘two-stage superconductivity’ feature as temperature decreases: a first-order superconducting transition occurs at a temperature T c that is followed by a sudden increase of the superconducting order parameter at a lower temperature T c ′ < T c . At the first stage, T c ′ < T < T c , the pairing function arises and the entropy is released only in the vicinity of the two Fermi surfaces; while at the second stage, T < T c ′ , the pairing function becomes significant and the entropy is further released in deep (single-occupied) region in the Fermi sea. The phase transitions are analyzed within the Ginzburg–Landau theory. Our work sheds new light on unconventional superconductivity in strongly correlated electrons.
Journal Article
كلنا في البداية جدد
المحتويات : كلنا في البداية جدد-لا نستغني عن الملح-الخطيئة الأصلية-الباب الخفي-السرعة-روح عيد الميلاد-قمر يقطر منه الماء-قيمة الحب أغلى-السعادة التي لا حدود لها-الحزن-محيط أرض نصف قطرها خمسمائة متر-في طرف السماء الغربي مفكرة تتحدث عن شينجانغ-الزمان والمكان والشخصية-الحب بلغ شيخوخته-الزهور العظام الشقة المبنية بالطوب الطيني-النصف الأول خذلان والنصف الآخر امتلاك-أنجبت ولدا-الحانة التي اعتدت الخروج منها ... وموضوعات أخرى.
Book
Free Radical Damage in Ischemia-Reperfusion Injury: An Obstacle in Acute Ischemic Stroke after Revascularization Therapy
Acute ischemic stroke is a common cause of morbidity and mortality worldwide. Thrombolysis with recombinant tissue plasminogen activator and endovascular thrombectomy are the main revascularization therapies for acute ischemic stroke. However, ischemia-reperfusion injury after revascularization therapy can result in worsening outcomes. Among all possible pathological mechanisms of ischemia-reperfusion injury, free radical damage (mainly oxidative/nitrosative stress injury) has been found to play a key role in the process. Free radicals lead to protein dysfunction, DNA damage, and lipid peroxidation, resulting in cell death. Additionally, free radical damage has a strong connection with inducing hemorrhagic transformation and cerebral edema, which are the major complications of revascularization therapy, and mainly influencing neurological outcomes due to the disruption of the blood-brain barrier. In order to get a better clinical prognosis, more and more studies focus on the pharmaceutical and nonpharmaceutical neuroprotective therapies against free radical damage. This review discusses the pathological mechanisms of free radicals in ischemia-reperfusion injury and adjunctive neuroprotective therapies combined with revascularization therapy against free radical damage.
Journal Article
Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (‒)-morphine
(‒)-Morphine, which is selected as an essential medicine by World Health Organization, is widely applied in the treatment of the pain-related diseases. Due to its synthetically challenging molecular architecture and important clinical role, extensive synthetic studies of morphine-type alkaloids have been conducted. However, catalytic asymmetric total synthesis of (‒)-morphine remains a long-standing challenge. Here, we disclose an efficient enantioselective total synthesis of (‒)-morphine in a longest linear sequence of 16 steps. The key transformation features a highly enantioselective Robinson annulation enabled by our spiro-pyrrolidine catalyst to rapidly construct the densely functionalized
cis
-hydrodibenzofuran framework containing vicinal stereocenters with an all-carbon quaternary center. This asymmetric approach provides an alternative strategy for the synthesis of (‒)-morphine and its analogues.
(‒)-Morphine is an essential medicine selected by the World Health Organization, however its catalytic asymmetric syntheses have been rarely reported. Here, the authors developed an intramolecular enantioselective Michael addition leading to (‒)-morphine in a longest linear sequence of 16 steps.
Journal Article
Canopy height, rather than neighborhood effects, shapes leaf herbivory in a tropical rainforest
Factors shaping the interspecific variations in herbivory have puzzled ecologists for decades and several hypotheses have been proposed to explain interspecific variation in leaf herbivory. In a tropical rainforest in Yunnan Province, China, we collected 6732 leaves from 129 species with canopy heights ranging from 1.6 to 65.0 m above the ground. We tested the role of canopy height, the diversity, composition and structural heterogeneity of neighbors and leaf traits in shaping the interspecific variations in herbivory. Results show that leaf herbivory decreased with canopy height and specific leaf area (SLA) and increased with leaf size. However, neighboring species’ diversity, composition, and structural heterogeneity showed no association with herbivory. Therefore, neither the visual apparency effect nor the associational resistance effect was detected in this hyperdiverse tropical rainforest. These findings highlight the importance of vertical structure in shaping herbivory patterns in natural communities.
Journal Article