Explore the vast range of titles available.

The Italian Consensus Position Statement on Diagnosis, Treatment and Prevention of Obesity in Children and Adolescents integrates and updates the previous guidelines to deliver an evidence based approach to the disease. The following areas were reviewed: (1) obesity definition and causes of secondary obesity; (2) physical and psychosocial comorbidities; (3) treatment and care settings; (4) prevention. The main novelties deriving from the Italian experience lie in the definition, screening of the cardiometabolic and hepatic risk factors and the endorsement of a staged approach to treatment. The evidence based efficacy of behavioral intervention versus pharmacological or surgical treatments is reported. Lastly, the prevention by promoting healthful diet, physical activity, sleep pattern, and environment is strongly recommended since the intrauterine phase.

Purpose From previous studies, we had observed that the number of biomedical engineers and technicians (BMETs) skilled in the maintenance of medical devices (MDs) were limited in sub-Saharan Africa (SSA) and that a likely parallelism existed between BME maintenance-related tasks and house chores mainly carried out by women in daily life. Our objective in carrying out this study was to understand underlying local cultural and social factors and domestic traditions interfering with the inclusion of women in the field of clinical and biomedical engineering (BME), and to identify existing gaps in opportunities for women in Engineering, Science and Technology (EST) in this region. Methods We carried out an online survey involving 51 respondents (70.6% women, 29.4% men), to investigate gender-biased and cultural perceptions of maintenance-related tasks among engineers/technologists/technicians in BME and other allied professions in SSA​. The survey was refined through focus groups and pilot tests to assess its validity, and then shared among specific associations of women in engineering and other bodies in EST, as well as some hospital communities and institutions. Results The survey brought to light evidence of prejudices against women in the society and workplace and showed that the adoption of our parallelism hypothesis has potential for increasing medical device maintenance practices in SSA hospitals. Conclusions There is an apparent need to further study the possible effects of this sociological model through leveraging local culture and domestic traditions in ways that could ultimately increase the leadership and numbers of women BMETs in SSA.

Celiac Disease (CD) occurs in patients with Type 1 Diabetes (T1D) ranging the prevalence of 4.4-11.1% versus 0.5% of the general population. The mechanism of association of these two diseases involves a shared genetic background: HLA genotype DR3-DQ2 and DR4-DQ8 are strongly associated with T1D, DR3-DQ2 with CD. The classical severe presentation of CD rarely occurs in T1D patients, but more often patients have few/mild symptoms of CD or are completely asymptomatic (silent CD). In fact diagnosis of CD is regularly performed by means of the screening in T1D patients. The effects of gluten-free diet (GFD) on the growth and T1D metabolic control in CD/T1D patient are controversial. Regarding of the GFD composition, there is a debate on the higher glycaemic index of gluten-free foods respect to gluten-containing foods; furthermore GFD could be poorer of fibers and richer of fat. The adherence to GFD by children with CD-T1D has been reported generally below 50%, lower respect to the 73% of CD patients, a lower compliance being more frequent among asymptomatic patients. The more severe problems of GFD adherence usually occur during adolescence when in GFD non compliant subjects the lowest quality of life is reported. A psychological and educational support should be provided for these patients.

Background Hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) is characterized by recurrent edema of unpredictable frequency and severity. Stress, anxiety, and low mood are among the triggering factors most frequently reported. Impaired regulation and processing of emotions, also known as alexithymia, may influence outcomes. The aim of this study was to confirm the presence of alexithymia and stress in children with C1-INH-HAE, to determine whether they are also present in children affected by other chronic diseases, and to investigate their relationship with C1-INH-HAE severity. Data from children with C1-INH-HAE ( n  = 28) from four reference centers in Italy were compared with data from children with type 1 diabetes (T1D; n  = 23) and rheumatoid arthritis (RA; n  = 25). Alexithymia was assessed using the Alexithymia Questionnaire for Children scale; perceived stress was assessed using the Coddington Life Event Scale for Children (CLES-C). Results Mean age (standard deviation [SD]) in the C1-INH-HAE, T1D, and RA groups was 11.8 (3.3), 11.7 (2.9), and 11.1 (2.6) years, respectively. Mean C1-INH-HAE severity score was 5.9 (2.1), indicating moderate disease. Alexithymia scores were similar among disease groups and suggestive of difficulties in identifying and describing emotions; CLES-C scores tended to be worse in C1-INH-HAE children. C1-INH-HAE severity was found to correlate significantly and positively with alexithymia ( p  = 0.046), but not with perceived stress. Alexithymia correlated positively with perceived stress. Conclusions Alexithymia is common in children with chronic diseases. In C1-INH-HAE, it may result in increased perceived stress and act as a trigger of edema attacks. Comprehensive management of C1-INH-HAE children should consider psychological factors.

The Clinical Interview on the Sense of Grip on Chronic Disease has been administered to 68 mothers of children affected by Hereditary Angioedema (C1-Inh HAE), Type 1 Diabetes (T1D), Juvenile Rheumatoid Arthritis (JRA). The objectives are to detect general features of the experience of parenting children with chronic illness as well as the specificities of this experience related to the different conditions. Four Profiles of Sense of Grip were identified: Adempitive, Controlling, Reactive, Dynamic. The Sense of Grip Interview is an effective clinical tool for understanding the characteristics of the disease in daily life, which can help clinicians to encourage family adjustment to disease.

This paper aims to investigate the role of the digital in facing the social and practical impact of COVID-19 pandemic on particularly fragile and affected realities, Third Sector Organizations (TSO), in a context pervaded by structural and socio-economic weaknesses, the Campania Region in the South of Italy. It analyzes the digital object as: 1. a process - digitization/digitalization and digital transformation; 2. a scenario - in which identities, activities and alternative spaces of use or data collection transit and are constructed; 3. skills and capabilities - as social capital and value. This re-framing work is intended to be a useful tool for reflecting on the role of digital in research processes, while also offering a contribution in the debate on the Third Sector in contexts of crisis, such as the one generated by the COVID-19 pandemic, that impacts its existence, activity, shape, and perspectives.

In this article I provide an example of gender research conducted by a mixed method in which the scientific explanation, the contextual understanding and the significant interpretation of the observed phenomenon within a theoretical frame of reference find their meeting point at the intersection of qualitative and quantitative approaches. By exploring a peculiar reality of Naples, the femminielli, men who feel and live like women and who could be included in the diverse transgender universe, I moved to a mixed research model in the inter-multidisciplinary perspective of gender studies. This model is characterized by disciplinary crossings and methodological contaminations and involves the use of hermeneutics, but it is controlled by statistical quantitative procedures. In particular, the theoretical framework chosen leads to an integration of psychological theories about gender with anthropological perspectives, to offer an interpretation of a phenomenon characterized by a very strong ethno-psycho-social connotation.

Purpose To validate and cross-culturally adapt the Italian version of the Psychological Impact of Dental Aesthetics Questionnaire (PIDAQ) among Italian young adults. Methods After translation, back translation, and cross-cultural adaptation of the English PIDAQ, a first version of the Italian questionnaire was pretested. The final Italian PIDAQ was administered to 598 subjects aged 18-30 years, along with two other instruments: the aesthetic component of the index of orthodontic treatment need (IOTN-AC) and the perception of occlusion scale (POS), which identified the self-reporting grade of malocclusion. Structural validity was assessed by means of factorial analysis, internal consistency was measured with Cronbach's alpha coefficient (α), convergent validity was assessed by means of Spearman correlation, and test-retest reliability was calculated with intra-class correlation coefficient (ICC) and standard measurement error. Criterion validity was evaluated by multivariate and univariate analysis of variance with Bonferroni post hoc tests. Results The α of the Italian PIDAQ domains ranged between 0.79 and 0.92. The ICC was between 0.81 and 0.90. The mean scores of each PIDAQ domain showed a statistically significant difference when analysed according to the IOTN-AC and POS scores. Conclusion The satisfactory psychometric properties make PIDAQ a usable tool for future studies on oral healthrelated quality of life among Italian young adults.

Aims Management of type 1 diabetes mellitus (T1DM) influences several aspects of life, such as adherence to healthy lifestyle habits and health-related quality of life (HRQoL). Our aim was to evaluate the association between unhealthy lifestyle habits and HRQoL in adolescents and young adults with T1DM. Methods Two hundred and forty-two Caucasian patients (13–19 years) consecutively enrolled over a 12-month period in three Regional Pediatric Diabetes Centers in Italy. Demographics, clinical, and laboratory parameters, adherence to lifestyle habits (Mediterranean Diet assessed by KIDMED, Physical Activity levels and sedentary behavior by questionnaire) considered either separately or in cluster, and HRQoL by Pediatric Quality of Life Inventory Diabetes Module (PedsQL 3.0 DM) were collected. Metabolic control was determined by HbA1c mean of previous year. Results Only 15 (6.2%) patients fulfilled the cluster of three healthy lifestyle habits without gender differences ( p  = 0.353); 62 (25.6%) had 1 unhealthy lifestyle habit, and 165 (68.2%) had ≥2. Adolescents meeting physical activity recommendations had better PedsQL scores than those who did not meet. PedsQL total score and specific sub-scales decreased in patients with unhealthy lifestyle habits. High PedsQL was significantly associated with being male, living in South Italy, having lower HbA1c mean levels, and reporting lower adherence to unhealthy lifestyle habits. Conclusions The clustering of unhealthy lifestyle habits is associated with reduced HRQoL in adolescents and young adults with T1DM. Promoting multiple behavior changes may be a useful approach to improve the health status and the HRQoL in youths with T1DM.