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Hypertension is currently rising steadily among the world population. The first level of screening to know whether one is suffering from hypertension is essential as this lays the foundation for the actual diagnosis. This research details the user interface design and usability evaluation of the hypertension management guideline. The proposed mobile application prototype assists people in screening themselves with regards to hypertension based on symptoms. This prototype also acts as a sharing platform for hypertension patients to help them share their concerns and advice within the related online community. The eye-tracker experiment was used to support the visual strategy of the prototype design. In studying the usability of the mobile application, an experiment carried out with two groups of people, of which one group of people have hypertension. In contrast, the other group of people do not have hypertension. An independent-samples t-test conducted to compare the user performance scores using the proposed prototype. Based on the usability study, both user groups understood and used the applications with ease. However, the findings revealed there was a significant difference in overall scores for hypertension patients and non-hypertension patients. The findings of this study could help software developer design an effective application for hypertension guideline tool for monitoring health and well-being.