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result(s) for
"al-Subayi, Nura Jiza"
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Postoperative complications in living liver donors : a retrospective study, single-center experience in Saudi Arabia
by
al-Thanayyan, Nuf Abd al-Aziz
,
al-Subayi, Nura Jiza
,
al-Thubayti, Ala
in
Adult
,
Anastomotic Leak - etiology
,
Body mass index
2019
Living donor liver transplantation (LDLT) offers life to patients with end-stage
liver disease. The balance between the benefit to the recipient and the risk to the donor plays a
central role in justifying LDLT. However, the incidence rates of complications posttransplant
differ widely. This study is designed to identify postoperative complications in LDLT in a tertiary
care center King Abdulaziz Medical City (KAMC). This was a retrospective cohort study. All
donors at KAMC between January 2003 and December 2015 were reviewed through a hospital
database and patient charts to determine the postoperative complications based on the modified
Clavien classification system. All donors were relatives of the recipients and assessed before the
surgery. A total of 101 donors underwent LDLT: 75 were male and 26 were female, with a mean
age of 27.7 ± 6.6. The breakdown of specific surgical procedures was as follows: 65 (64.3%)
donors underwent right hepatic lobectomy, 31 (30.6%) underwent left lateral hepatectomy, three
(2.97%) underwent extended right hepatectomy with the inclusion of the middle hepatic vein, and
two (1.98%) underwent left hepatectomy. Postoperative complications were determined in 20
patients (19.8%), but no mortality was observed. Complications were reported in 14 (21.5%) right
and six (19.4%) left lateral hepatectomy donors. A total of 12 patients had Grade I complications, six patients had Grade II complications, and Grade III complications were reported in two cases.
The most frequent complications were upper
limb weakness to brachial plexus neuropathy
and mild bile leak. Life-threatening compli- cations in our center have not been reported in
LDLT; however, some donors may experience
postoperative morbidity, which usually were
mild and had a good prognosis.
Journal Article