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Acute toxicity is a frequent but avoidable cause of morbidity and mortality in children, especially in developing countries such as India. The present study assesses patterns of acute toxicity among children of different age groups. The study sample included all hospitalised paediatric victims of acute accidental poisoning at the King George Medical University, Lucknow, India from 2010-2011. Their histories, baseline characteristics, clinical treatments and outcomes were reviewed. Most children were males less than three years of age with 4% overall mortality. Kerosene oil was implicated in most cases. Childhood poisoning was common among patients 1-3 years of age with a male preponderance. The accidental ingestion of household poisons, especially kerosene oil, was responsible for most cases. Parents must be educated about the dangers of these toxic household substances and warned to store them in suitable containers out of the reach of children.