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"مضادات الأكسدة"
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Effects of Bidens Pilosa L Extract on Complete Blood Count and Serum Antioxidant Enzymes Levels in Rats
The aim of this study is to investigate the effects of Bidens Pilosa L extract (BPE) on complete blood picture and serum antioxidant enzymes level in rats by the dose of (3, 6 and 9ml orally/day). Thirty tow male albino rats about (170±10g) were used in this study, and then divided into four equal groups each (8rats). The first one considers a control negative group that fed on a basal diet all the time during the experiment, the other groups (24 rats) was fed on a basal diet + the Oral doses of B. Pilosa for (4 weeks). Complete blood cells count levels (HB, HCT, RBCs and PLT) showed significant increases compared with the control group. WBCs showed a decrease. For antioxidant enzymes (SOD, CAT, GSH and GPx) were significantly increase comparing with control.
Journal Article
Therapeutic Potential of Boswellia Papyrifera Fractions in Acetaminophen-Induced Nephrotoxicity
Boswellia papyrifera, commonly known as frankincense, has a rich history in herbal medicine for its anti-inflammatory and antioxidant properties, showing promise in managing various health conditions. However, its specific role in kidney damage management, particularly in acetaminophen-induced nephrotoxicity, remains unclear. This study aims to evaluate the nephrocurative effects of ethyl acetate fractions (E2) derived from Boswellia papyrifera stem bark extract in rats with acetaminophen-induced nephrotoxicity. Column chromatography was conducted, yielding sub-fractions (E2A, E2B, E2C, and E2D) and were administered orally to rats for four weeks after induction of kidney damage. Urea and creatinine levels were measured enzymatically via Jaffe methods, while electrolytes were determined using colorimetric and titrimetric methods. Antioxidants were assessed using spectroscopic techniques. Results indicated significant increases in serum creatinine, urea, sodium, and potassium, with a decrease in bicarbonate in the acetaminophen-induced group. Antioxidant enzyme activities decreased, and malondialdehyde levels increased in this group confirming the induction of kidney damage. Oral administration of E2B fraction showed significant increases in antioxidant enzyme activity and decreases in MDA, serum creatinine, urea, potassium, and sodium levels in all groups. No significant effects were observed with other fractions. Histopathological examination supported the biochemical findings. The study concludes that the E2B ethyl acetate fraction of Boswellia papyrifera stem bark exhibits nephroprotective effects against acetaminophen-induced nephrotoxicity and acts as a potent antioxidant.
Journal Article
مضادات الأكسدة : صحتك، شبابك، وجمالك
هذا الكتاب طبيبك حيثما كنت : طبيبك ومرشدك الصحي بين يديك يوفر لك مرجعا علميا يجيب على أسئلتك حول الغذاء والصحة. يعرفك بميزات الغذاء وقدرته الخارقة على الوقاية من الأمراض وشفائها. يعرفك بالغذاء الصحي وأسلوب الحياة الصحيح لتتحقق لك ولأسرتك السلامة من الأمراض. يطلعك على دور النباتات الطبية واستعمالاتها المتعددة. يذكر لك الكثير من المراجع العلمية الأساسية قديمها وحديثها وآيات قرآنية كريمة وأحاديث نبوية شريفة وخبرات تراثية وتجارب شخصية.
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