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肺癌是一种身心疾病，个性、行为特征和精神心理因素与肺癌的发生、发展关系密切。许多研究证实，肺癌确诊后长期存活患者的预后也与他们的身心状态和表现有紧密联系。我们调查了42例肺癌确诊后长期存活（≥5年）患者的精神心理、个性和行为特征，并与近一年内确诊后仍存活的47例同病患者以及健康人群作比较，试图总结前者身心表现的一般规律。

Pulmonary alveolar microlithiasis is a rare disease characterized by intra-alveolar presence of microliths. This study reports an interesting case of pulmonary alveolar microlithiasis and provides a systematic review of cases reported from India. A 23-year-old female presented with a history of cough, wheeze, chest pain, and episodic wheeze for five months. Pulmonary function tests demonstrated an obstructive pattern, and chest X- ray showed fine micronodular opacities predominantly involving the middle and lower zones of both lungs. Transbronchial lung biopsy revealed the diagnosis. She responded well to inhaled steroid therapy. A systematic review of literature was performed and identified 73 cases of pulmonary alveolar microlithiasis reported from India. The mean （SD） age of the patients was 28.8 （14.9） years, with an almost equal male：female ratio. Many patients were asymptomatic at presentation. Breathlessness and cough were the most common symptoms, and the disease progressed into respiratory failure associated with cor pulmonale. About one-third of the cases were initially misdiagnosed and treated as pulmonary tuberculosis. Extra-pulmonary manifestations and co- morbidities were also evident in our series. This systematic review helps to determine epidemiological and clinical characteristics of pulmonary alveolar microlithiasis. Further research is needed to elucidate the etiopathogenesis, diagnosis, and therapeutic options, which are beneficial in developing and identifying cost- effective treatment for pulmonary alveolar microlithiasis.

原发性支气管肺癌首发常见症状是咳嗽、咳痰、咯血等呼吸道表现。吞咽困难是食管癌的典型临床症状,极少数原发性支气管肺癌患者由于肿瘤进展在病程后期可以出现此症状。本文报道1例特殊的肺癌病例,患者以吞咽困难为首发症状就医,胃镜检查发现食管粘膜隆起、表面溃疡,病理活检提示鳞状细胞癌,以食管癌收入院,行进一步检查后确诊为原发性支气管肺癌。

《中国现代神经疾病杂志》新开辟的“临床医学图像”栏目，主要报道少见病例的典型影像及病理表现，或常见病例的特殊影像及病理表现，包括x线、CT、MRI、超声、放射性核素显像以及组织形态、免疫组织化学等。每篇文章需提供2～6帧图片及详细图解；文字部分简要描述患者的主要临床症状、异常体征及经病理或其他临床科学手段证实的诊断结果；

抑郁症是以情绪低落，兴趣缺乏，乐趣丧失为核心症状的疾病。临床表现可分为核心症状、心理症状群与躯体症状群三方面。随着现代城市生活节奏不断地加快，人们生活压力越来越大，抑郁症的发病率也在逐年递增。据世界卫生组织估计，到2020年，抑郁症可能成为仅次于冠心病的第二大疾病。影响到全球20％的人群。

发作性睡病是一个慢性神经变性并且可能有自身免疫介导的终身性疾病,临床表现为病程初期睡眠增多,病程初期或随后出现猝倒（强烈情感刺激导致的肌肉失张力）[1],可能出现的症状有入睡前或觉醒前幻觉、睡眠瘫痪、夜间睡眠问题（生动的梦境、夜间经常觉醒）、性格和行为改变、肥胖、认知障碍、性早熟[2],约10％的患者出现四大症状[3-4].临床较为少见,容易出现误诊.