Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
15,482
result(s) for
"1958"
Sort by:
My Degeneration
They say, \"It is better to light a single candle than to curse the darkness.\" Peter Dunlap-Shohl counters, \"Why not do both?\".
eBook
The eclipse I call father : essays on absence
\"A collection of essays exploring the concept of absence, ranging across topics as diverse as marriage, Japanese poetry, Craftsman design, Old English riddles, racism, extinction, fatherhood, mountaineering, predatory mega-fauna, street fighting, trains, the Great Depression, and the effects of climate change\"-- Provided by publisher.
Book
Keith Coventry
With this publication, Keith Coventry (*1958, Burnley, Great Britain) presents an overview of his oeuvre from its beginnings in the early 1990s to the present day, shedding light on his exploration of the legacy of modernism and post-modernism. In his series 'Junk Paintings' (2012), for example, a new visual vocabulary containing elements of the famous McDonald's logo shifts into focus, blending with Minimalism and Pop Art. In the white 'Pure Junk Paintings' (2015/16) he continues his work with these formal elements, but using new materials: wood, muslin, beeswax, glass, and gesso lend the paintings a sculptural presence. The same is true of the series 'Golden Arches' (2016), for which parts of the McDonald's logo were cast in bronze and heavily gold plated, contrasting a cheap, mass produced commodity with materials representing permanence, craft, and value. In Coventry's art the consumer world and mass production encounter an aesthetic characterized by beauty and timelessness.
BOOK
من زوايا الذاكرة : على هامش ثورة 14 تموز عام 1958
بدأ صباح 14 تموز الباكر كغيره من أيام العقد الخامس من القرن الماضي كانت الشائعات تملأ زوايا وخلايا السياسة والأدب والمجتمع كلها فالكل يتوقع أن نوري السعيد يعد ليبطش من جديد على الرغم من أنه ترك رئاسة وزارة العراق ليغدو رئيسا لوزارة الاتحاد العربي الهاشمي الوليد وأسناد الوزارة لأحد أخلص مريديه وهو عبد الوهاب مرجان إلا أنه ما يزال طباخ السياسة العراقية التي تسير إلى نهج جديد من العنف وربما المذابح فرجل السياسة العراقية العجوز عنيد وهذه هي فرصته الجديدة لتنظيف البلد مما يعدها بؤرا شيوعية بلباس جديد فالأيديلوجيات التي اكتسحت وسيطرت على عقول الفئات الشابة هي السرطان الذي لابد من استئصاله حسب رأيه وكان هناك هياج شعبي ممزوج بالقلق والريبة وتوقعات ببطش مبرمج لا سيما وأن حلف بغداد أصبح واقعا وغدا نوري السعيد لولبه الرئيس.
Book
Human 5′ UTR design and variant effect prediction from a massively parallel translation assay
The ability to predict the impact of cis-regulatory sequences on gene expression would facilitate discovery in fundamental and applied biology. Here we combine polysome profiling of a library of 280,000 randomized 5′ untranslated regions (UTRs) with deep learning to build a predictive model that relates human 5′ UTR sequence to translation. Together with a genetic algorithm, we use the model to engineer new 5′ UTRs that accurately direct specified levels of ribosome loading, providing the ability to tune sequences for optimal protein expression. We show that the same approach can be extended to chemically modified RNA, an important feature for applications in mRNA therapeutics and synthetic biology. We test 35,212 truncated human 5′ UTRs and 3,577 naturally occurring variants and show that the model predicts ribosome loading of these sequences. Finally, we provide evidence of 45 single-nucleotide variants (SNVs) associated with human diseases that substantially change ribosome loading and thus may represent a molecular basis for disease.
Journal Article