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In single-cell analysis, cellular activity and parameters are assayed on an individual, rather than population-average basis. Essential to observing the activity of these cells over time is the ability to trap, pattern and retain them, for which previous single-cell-patterning work has principally made use of mechanical methods. While successful as a long-term cell-patterning strategy, these devices remain essentially single use. Here we introduce a new method for the patterning of multiple spatially separated single particles and cells using high-frequency acoustic fields with one cell per acoustic well. We characterize and demonstrate patterning for both a range of particle sizes and the capture and patterning of cells, including human lymphocytes and red blood cells infected by the malarial parasite Plasmodium falciparum . This ability is made possible by a hitherto unexplored regime where the acoustic wavelength is on the same order as the cell dimensions. Single cell trapping is very useful in biomedical applications, but to date this can only be done via mechanical traps. Here, Collins et al. use a two-dimensional acoustic field with wavelength comparable to cell size to pattern one cell per well in a microfluidic grid.

Controlling audible sound requires inherently broadband and subwavelength acoustic solutions, which are to date, crucially missing. This includes current noise absorption methods, such as porous materials or acoustic resonators, which are typically inefficient below 1 kHz, or fundamentally narrowband. Here, we solve this vexing issue by introducing the concept of plasmacoustic metalayers. We demonstrate that the dynamics of small layers of air plasma can be controlled to interact with sound in an ultrabroadband way and over deep-subwavelength distances. Exploiting the unique physics of plasmacoustic metalayers, we experimentally demonstrate perfect sound absorption and tunable acoustic reflection over two frequency decades, from several Hz to the kHz range, with transparent plasma layers of thicknesses down to λ /1000. Such bandwidth and compactness are required in a variety of applications, including noise control, audio-engineering, room acoustics, imaging and metamaterial design. Controlling audible sound requires inherently broadband and subwavelength acoustic solutions. Exploiting the unique physics of plasmacoustic metalayers, we experimentally demonstrate versatile and tunable sound control over a wide frequency range.

The addition of active, nonlinear, and nonreciprocal functionalities to passive piezoelectric acoustic wave technologies could enable all-acoustic and therefore ultra-compact radiofrequency signal processors. Toward this goal, we present a heterogeneously integrated acoustoelectric material platform consisting of a 50 nm indium gallium arsenide epitaxial semiconductor film in direct contact with a 41° YX lithium niobate piezoelectric substrate. We then demonstrate three of the main components of an all-acoustic radiofrequency signal processor: passive delay line filters, amplifiers, and circulators. Heterogeneous integration allows for simultaneous, independent optimization of the piezoelectric-acoustic and electronic properties, leading to the highest performing surface acoustic wave amplifiers ever developed in terms of gain per unit length and DC power dissipation, as well as the first-ever demonstrated acoustoelectric circulator with an isolation of 46 dB with a pulsed DC bias. Finally, we describe how the remaining components of an all-acoustic radiofrequency signal processor are an extension of this work. Radio frequency signal processing (RFSP) currently involves a mix of components with differing operation principles, which hinders miniaturisation. Here, Hackett et al. succeed in creating acoustic non-reciprocal circulators, amplifiers, and passive filters, paving the way for all acoustic single-chip RFSP.

Acoustic holograms are the keystone of modern acoustics. They encode three-dimensional acoustic fields in two dimensions, and their quality determines the performance of acoustic systems. Optimisation methods that control only the phase of an acoustic wave are considered inferior to methods that control both the amplitude and phase of the wave. In this paper, we present Diff-PAT, an acoustic hologram optimisation platform with automatic differentiation. We show that in the most fundamental case of optimizing the output amplitude to match the target amplitude; our method with only phase modulation achieves better performance than conventional algorithm with both amplitude and phase modulation. The performance of Diff-PAT was evaluated by randomly generating 1000 sets of up to 32 control points for single-sided arrays and single-axis arrays. This optimisation platform for acoustic hologram can be used in a wide range of applications of PATs without introducing any changes to existing systems that control the PATs. In addition, we applied Diff-PAT to a phase plate and achieved an increase of > 8 dB in the peak noise-to-signal ratio of the acoustic hologram.

Topological modes (TMs) are usually localized at defects or boundaries of a much larger topological lattice 1 , 2 . Recent studies of non-Hermitian band theories unveiled the non-Hermitian skin effect (NHSE), by which the bulk states collapse to the boundary as skin modes 3 – 6 . Here we explore the NHSE to reshape the wavefunctions of TMs by delocalizing them from the boundary. At a critical non-Hermitian parameter, the in-gap TMs even become completely extended in the entire bulk lattice, forming an ‘extended mode outside of a continuum’. These extended modes are still protected by bulk-band topology, making them robust against local disorders. The morphing of TM wavefunction is experimentally realized in active mechanical lattices in both one-dimensional and two-dimensional topological lattices, as well as in a higher-order topological lattice. Furthermore, by the judicious engineering of the non-Hermiticity distribution, the TMs can deform into a diversity of shapes. Our findings not only broaden and deepen the current understanding of the TMs and the NHSE but also open new grounds for topological applications. It is experimentally demonstrated that the non-Hermitian skin effect can convert localized topological modes into extended modes of unconventional shapes while preserving the topological characteristics, which presents opportunities for topological manipulations of waves and light.

One property of electromagnetic waves that has been recently explored is the ability to multiplex multiple beams, such that each beam has a unique helical phase front. The amount of phase front ‘twisting’ indicates the orbital angular momentum state number, and beams with different orbital angular momentum are orthogonal. Such orbital angular momentum based multiplexing can potentially increase the system capacity and spectral efficiency of millimetre-wave wireless communication links with a single aperture pair by transmitting multiple coaxial data streams. Here we demonstrate a 32-Gbit s −1 millimetre-wave link over 2.5 metres with a spectral efficiency of ~16 bit s −1  Hz −1 using four independent orbital–angular momentum beams on each of two polarizations. All eight orbital angular momentum channels are recovered with bit-error rates below 3.8 × 10 −3 . In addition, we demonstrate a millimetre-wave orbital angular momentum mode demultiplexer to demultiplex four orbital angular momentum channels with crosstalk less than −12.5 dB and show an 8-Gbit s −1 link containing two orbital angular momentum beams on each of two polarizations. High speed data transmission using orbital angular momentum beams has been recently demonstrated. Here, Yan et al. demonstrate a 32 Gbit/s millimetre-wave communication link using eight coaxially propagating independent orbital angular momentum beams with four orbital angular momentum states on two orthogonal polarizations.

The proposed work enumerates a hybrid thin, deep-subwavelength (2 cm) acoustic metamaterials acting as a completely new type of sound absorber, showing multiple broadband sound absorption effects. Based on the fractal distribution of Helmholtz resonator (HRs) structures, integrated with careful design and construct hybrid cross micro-perforated panel (CMPP) that demonstrate broad banding approximately one-octave low-frequency sound absorption behavior. To determine the sound absorption coefficient of this novel type of metamaterial, the equivalent impedance model for the fractal cavity and the micro-perforated Maa’s model for CMPP are both used. We validate these novel material designs through numerical, theoretical, and experimental data. It is demonstrated that the material design possesses superior sound absorption which is primarily due to the frictional losses of the structure imposed on acoustic wave energy. The peaks of different sound absorption phenomena show tunability by adjusting the geometric parameters of the fractal structures like cavity thickness ‘ t ’, cross perforation diameter of micro perforated panel, etc. The fractal structures and their perforation panel are optimized dimensionally for maximum broadband sound absorption which is estimated numerically. This new kind of fractals cavity integrated with CMPP acoustic metamaterial has many applications as in multiple functional materials with broad-band absorption behavior etc.

Exceptional points and skin effect, as the two distinct hallmark features unique to the non-Hermitian physics, have each attracted enormous interests. Recent theoretical works reveal that the topologically nontrivial exceptional points can guarantee the non-Hermitian skin effect, which is geometry-dependent, relating these two unique phenomena. However, such novel relation remains to be confirmed by experiments. Here, we realize a non-Hermitian phononic crystal with exceptional points, which exhibits the geometry-dependent skin effect. The exceptional points connected by the bulk Fermi arcs, and the skin effects with the geometry dependence, are evidenced in simulations and experiments. Our work, building an experimental bridge between the exceptional points and skin effect and uncovering the unconventional geometry-dependent skin effect, expands a horizon in non-Hermitian physics. Recent theoretical works reveal that the topologically nontrivial exceptional points can guarantee the geometry-dependent skin effect, but it remains to be confirmed by experiments. Here the authors realize a reciprocal non-Hermitian phononic crystal with exceptional points, and observe the geometry-dependent skin effect.

Suppressing broadband low-frequency sound has great scientific and engineering significance. However, normal porous acoustic materials backed by a rigid wall cannot really play its deserved role on low-frequency sound absorption. Here, we demonstrate that an ultrathin sponge coating can achieve high-efficiency absorptions if backed by a metasurface with moderate surface impedance. Such a metasurface is constructed in a wide frequency range by integrating three types of coiled space resonators. By coupling an ultrathin sponge coating with the designed metasurface, a deep-subwavelength broadband absorber with high absorptivity ( > 80 % ) exceeding one octave from  185 Hz to  385 Hz (with wavelength λ from 17.7 to 8.5 times of thickness of the absorber) has been demonstrated theoretically and experimentally. The construction mechanism is analyzed via coupled mode theory. The study provides a practical way in constructing broadband low-frequency sound absorber.

Systems coupled to multiple thermodynamic reservoirs can exhibit nonequilibrium dynamics, breaking detailed balance to generate currents. To power these currents, the entropy of the reservoirs increases. The rate of entropy production, or dissipation, is a measure of the statistical irreversibility of the nonequilibrium process. By measuring this irreversibility in several biological systems, recent experiments have detected that particular systems are not in equilibrium. Here we discuss three strategies to replace binary classification (equilibrium versus nonequilibrium) with a quantification of the entropy production rate. To illustrate, we generate time-series data for the evolution of an analytically tractable bead-spring model. Probability currents can be inferred and utilized to indirectly quantify the entropy production rate, but this approach requires prohibitive amounts of data in high-dimensional systems. This curse of dimensionality can be partially mitigated by using the thermodynamic uncertainty relation to bound the entropy production rate using statistical fluctuations in the probability currents. The determination of entropy production from experimental data is a challenge but a recently introduced theoretical tool, the thermodynamic uncertainty relation, allows one to infer a lower bound on entropy production. Here the authors provide a critical assessment of the practical implementation of this tool.