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Aging in world history
\"Contemporary concerns about aging societies have stimulated interest in past ways of growing old, and whilst historians have investigated the experience of the aged, cultural representations of old age, and the phenomenon of demographic ageing, however the literature has been overwhelmingly western. This study reviews the world-wide literature on aging and seeks to move beyond received wisdom about attitudes and experiences running from the ancient world to the present.Aging in World History will introduce students and general readers to historical ways of thinking about aging in two senses: the experience of individuals and the transformation of populations. The first section introduces theoretical concerns, understandings of \"natural\" or \"traditional\" ways of growing old, and diverse cultural prescriptions and representations. The second section covers key issues from the medieval to the early modern era. The third section looks at transitions to modernity, whilst the final part explores the contemporary world, before concluding with an overview of past, present and future\"-- Provided by publisher.
Book
Growing Old in a New China
Growing Old in a New China: Transitions in Elder Care is an accessible exploration of changing care arrangements in China. Combining anthropological theory, ethnographic vignettes, and cultural and social history, it sheds light on the growing movement from home-based to institutional elder care in urban China. The book examines how tensions between old and new ideas, desires, and social structures are reshaping the experience of caring and being cared for. Weaving together discussions of family ethics, care work, bioethics, aging, and quality of life, this book puts older adults at the center of the story. It explores changing relationships between elders and themselves, their family members, caregivers, society, and the state, and the attempts made within and across these relational webs to find balance and harmony. The book invites readers to ponder the deep implications of how and why we care and the ways end-of-life care arrangements complicate both living and dying for many elders.
eBook
Aging Gracefully in the Renaissance: Stories of Later Life from Petrarch to Montaigne
InAging Gracefully in the Renaissance: Stories of Later Life from Petrarch to MontaigneCynthia Skenazi explores a shift in attitudes towards aging and provides a historical perspective on a crucial problem of our time.
eBook
Winter dreams : a historical guide to old age
'Winter Dreams' is an evocative history of the ways the old have thought, felt and expressed themselves over two millennia, tracking the experience of ageing through artistic, literary and historical records. While old age is often depicted as 'sans teeth, sans eyes, sans taste, sans everything', Barbara H. Rosenwein shows that the elderly have always retained their emotional depth and desires. She explores how these have changed over time, as societies' views of the elderly and of a 'good' old age have changed. And through careful exegesis, she allows the elderly, so often absent from the historical record, to speak to us. We live in a rapidly ageing society, yet ageism is rampant and death and dying are taboo subjects. Rosenwein's book is a finely wrought testimony to the value of ageing and the richness of our 'Winter Dreams'.
BOOK
Age in America
Eighteen. Twenty-one. Sixty-five. In America today, we recognize these numbers as key transitions in our lives-precise moments when our rights and opportunities change-when we become eligible to cast a vote, buy a drink, or enroll in Medicare.This volume brings together scholars of childhood, adulthood, and old age to explore how and why particular ages have come to define the rights and obligations of American citizens.
Since the founding of the nation, Americans have relied on chronological age to determine matters as diverse as who can marry, work, be enslaved, drive a car, or qualify for a pension. Contributors to this volume explore what meanings people in the past ascribed to specific ages and whether or not earlier Americans believed the same things about particular ages as we do. The means by which Americans imposed chronological boundaries upon the variable process of growing up and growing old offers a paradigmatic example of how people construct cultural meaning and social hierarchy from embodied experience. Further, chronological age always intersects with other socially constructed categories such as gender, race, and sexuality. Ranging from the seventeenth century to the present, taking up a variety of distinct subcultures-from frontier children and antebellum slaves to twentieth-century Latinas-Age in America makes a powerful case that age has always been a key index of citizenship.
eBook
Old age, new science : gerontologists and their biosocial visions, 1900-1960
\"Between 1870 and 1940, life expectancy in the United States skyrocketed while the percentage of senior citizens age sixty-five and older more than doubled--a phenomenon owed largely to innovations in medicine and public health. At the same time, the Great Depression was a major tipping point for age discrimination and poverty in the West: seniors were living longer and retiring earlier, but without adequate means to support themselves and their families. The economic disaster of the 1930s alerted scientists, who were actively researching the processes of aging, to the profound social implications of their work--and by the end of the 1950s, the field of gerontology emerged. Old Age, New Science explores how a group of American and British life scientists contributed to gerontology's development as a multidisciplinary field. It examines the foundational \"biosocial visions\" they shared, a byproduct of both their research and the social problems they encountered. Hyung Wook Park shows how these visions shaped popular discourses on aging, directly influenced the institutionalization of gerontology, and also reflected the class, gender, and race biases of their founders\"-- Provided by publisher.
Book
Nrf2, a Guardian of Healthspan and Gatekeeper of Species Longevity
Although aging is a ubiquitous process that prevails in all organisms, the mechanisms governing both the rate of decline in functionality and the age of onset remain elusive. A profound constitutively upregulated cytoprotective response is commonly observed in naturally long-lived species and experimental models of extensions to lifespan (e.g., genetically-altered and/or experimentally manipulated organisms), as indicated by enhanced resistance to stress and upregulated downstream components of the cytoprotective nuclear factor erythroid 2-related factor 2 (Nrf2)-signaling pathway. The transcription factor Nrf2 is constitutively expressed in all tissues, although levels may vary among organs, with the key detoxification organs (kidney and liver) exhibiting highest levels. Nrf2 may be further induced by cellular stressors including endogenous reactive-oxygen species or exogenous electrophiles. The Nrf2-signaling pathway mediates multiple avenues of cytoprotection by activating the transcription of more than 200 genes that are crucial in the metabolism of drugs and toxins, protection against oxidative stress and inflammation, as well as playing an integral role in stability of proteins and in the removal of damaged proteins via proteasomal degradation or autophagy. Nrf2 interacts with other important cell regulators such as tumor suppressor protein 53 (p53) and nuclear factor-kappa beta (NF-κB) and through their combined interactions is the guardian of healthspan, protecting against many age-related diseases including cancer and neurodegeneration. We hypothesize that this signaling pathway plays a critical role in the determination of species longevity and that this pathway may indeed be the master regulator of the aging process.
Journal Article
The National Alzheimer's Coordinating Center (NACC) 1999–2025: Personal history and recollections
INTRODUCTION The National Alzheimer's Coordinating Center (NACC), founded in 1999 by the author, has many collaborators and contributors. NACC worked with Alzheimer's Disease Research Centers (ADRCs) to establish and maintain standardized, rigorous data collection, primarily through the Uniform Data Set. Clinical expertise was provided by the National Institute on Aging (NIA)/ADRC Clinical Task Force. Collaboration and leadership of many individuals was necessary for the content and context validity for NACC and NACC data. METHODS This paper includes personal insights, recollections, and milestones in a casual narrative conversation. It does not chronicle exact dates of experiences nor achievements. The author mentions just a few of the many great people and forces that shaped and sustained NACC. RESULTS The NIA, ADRCs, and NACC are a network of collaboration, communication, and worldwide data sharing. It will have lasting impact on the Alzheimer's disease and related dementias field. DISCUSSION NACC's ≈ 1500 publications are available on PubMed by searching U01 AG016976 and U24 AG072122. Highlights The first stages in forming National Alzheimer's Coordinating Center (NACC) data collection were formation of the Minimum Data Set and the neuropathology data set. The challenges in development of the Uniform Data Set (UDS) as the basic data collection mechanism for all the National Institute on Aging Alzheimer's Disease Research Centers (ADRCs) were substantial and involved all ADRCs. The critical role of the Clinical Task Force was to establish not only UDS content but to cement the overall importance of the UDS as the “cornerstone” of NACC and the ADRC program. Since 2021 there have been new informatics innovations, novel data streams and the development of the Data Front Door.
Journal Article