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The Principles and Practice of Antiaging Medicine for the Clinical Physician
This book takes a whole new perspective concerning the approach to treating aging process. Most doctors feel they have no other options but to operate on the physical processes that occur as we grow older. Now, for the first time, there is another scientific approach that impacts on the causes of aging and not just on the effects.
eBook
Anti-ageing nutrients
Ageing is a complex, time-related biological phenomenon that is genetically determined and environmentally modulated. According to even the most pessimistic projections, average lifespan is expected to increase around the world during the next 20 years, significantly raising the number of aged individuals. But increasing life expectancy presents new problems, and industrialized countries are facing a pronounced increase in lifestyle diseases which constitute barriers to healthy ageing.
Anti-Ageing Nutrients: Evidence-based Prevention of Age-Associated Diseases is written by a multi-disciplinary group of researchers, all interested in the nutritional modulation of ageing mechanisms. Structured in three parts, Part 1 looks at the cellular modifications that underlie senescence of cells and ageing of the organisms; the effects of energy restriction on cellular and molecular mechanisms and in the whole organism; and the epigenetic modifications associated with ageing. Part 2 includes chapters which discuss the nutritional modulation of age-associated pathologies and the functional decline of organs, with a focus on those primarily affected by chronological ageing. Part 3 summarises the knowledge presented in the previous chapters and considers the best diet pattern for the aged individuals.
The book reflects the most recent advances in anti-ageing nutrition and will be a valuable resource for professionals, educators and students in the health, nutritional and food sciences.
eBook
How not to age : the scientific approach to getting healthier as you get older
\"Uncover the evidence-based science to slowing the effects of aging, from the New York Times bestselling author of the How Not to Die series When Dr. Michael Greger, founder of NutritionFacts.org, dove into the top peer-reviewed anti-aging medical research, he realized that diet could regulate every one of the most promising strategies for combating the effects of aging. We don't need Big Pharma to keep us feeling young-we already have the tools. In How Not to Age, the internationally renowned physician and nutritionist breaks down the science of aging and chronic illness and explains how to help avoid the diseases most commonly encountered in our journeys through life. Physicians have long treated aging as a malady, but getting older does not have to mean getting sicker. There are eleven pathways for aging in our bodies' cells and we can disrupt each of them. Processes like autophagy, the upcycling of unusable junk, can be boosted with spermidine, a compound found in tempeh, mushrooms, and wheat germ. Senescent \"zombie\" cells that spew inflammation and are linked to many age-related diseases may be cleared in part with quercetin-rich foods like onions, apples, and kale. And we can combat effects of aging without breaking the bank. Why spend a small fortune on vitamin C and nicotinamide facial serums when you can make your own for up to 2,000 times cheaper? Inspired by the dietary and lifestyle patterns of centenarians and residents of \"blue zone\" regions where people live the longest, Dr. Greger presents simple, accessible, and evidence-based methods to preserve the body functions that keep you feeling youthful, both physically and mentally. Brimming with expertise and actionable takeaways, How Not to Age lays out practical strategies for achieving ultimate longevity\"-- Provided by publisher.
Book
Circadian Lighting Was Associated with a Reduction in the Number of Hospitalized Patients Experiencing Falls: A Retrospective Observational Study
Background: Falls in hospitalized patients are a significant healthcare concern. This study examined whether circadian lighting, which helps to regulate circadian rhythms, reduces fall risk. Methods: A retrospective study was conducted in a 49-bed subacute and rehabilitation ward after the renovation and the installation of circadian lighting. Patients admitted during the five months with circadian lighting (intervention group) were compared to those admitted in the previous five months under fluorescent lighting (control group). Circadian lighting was defined as at least 275 equivalent melanopic lux between 7 a.m. and 12 p.m. Results: Significantly fewer patients in the intervention group experienced falls (7.4% vs. 15.0%, p = 0.0182). Logistic regression analysis identified circadian lighting as a protective factor (adjusted odds ratio [aOR] = 0.558, 95% confidence interval [CI]: 0.351–0.887, p = 0.0137), while age ≥ 80 (aOR = 2.48, 95% CI: 1.18–5.21, p = 0.0167) and anticonvulsant use (aOR = 3.68, 95% CI: 1.39–9.72, p = 0.0087) were significant risk factors. Conclusion: Circadian lighting was associated with a reduction in the number of patients who experienced falls, while advanced age and anticonvulsant use were significant risk factors.
Journal Article
Methuselah's zoo : what nature can teach us about living longer, healthier lives
\"A natural history of longevity in a wide variety of species along with an exploration of what we can learn from other species to preserve and extend human health\"-- Provided by publisher.
Book
Pharmacological and Behavioral Interventions to Mitigate Premature Aging in Patients with HIV
Purpose of Review
We sought to review pharmacological and behavioral interventions that have been publicly presented, published, or are currently ongoing to prevent or mitigate the effect of premature HIV-associated comorbidities.
Recent Findings
Multiple studies have been conducted in hopes of finding an effective intervention. While the choice of antiretroviral regimen influences recovery of immune function, several drugs used as adjunct treatments have proven effective to mitigate premature aging. Additionally, few behavioral interventions have exhibited some efficacy.
Summary
Statins, angiotensin-receptor blockers, and anti-hyperglycemic agents as well as optimal adherence, exercise, and intermittent fasting among others have had beneficial impact on markers of immune activation and levels of inflammatory biomarkers. However, several investigations had inconclusive outcomes so further studies with larger sample sizes are warranted.
Journal Article