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Gamma-ray bursts (GRBs) are brief flashes of γ-rays and are considered to be the most energetic explosive phenomena in the Universe1. The emission from GRBs comprises a short (typically tens of seconds) and bright prompt emission, followed by a much longer afterglow phase. During the afterglow phase, the shocked outflow—produced by the interaction between the ejected matter and the circumburst medium—slows down, and a gradual decrease in brightness is observed2. GRBs typically emit most of their energy via γ-rays with energies in the kiloelectronvolt-to-megaelectronvolt range, but a few photons with energies of tens of gigaelectronvolts have been detected by space-based instruments3. However, the origins of such high-energy (above one gigaelectronvolt) photons and the presence of very-high-energy (more than 100 gigaelectronvolts) emission have remained elusive4. Here we report observations of very-high-energy emission in the bright GRB 180720B deep in the GRB afterglow—ten hours after the end of the prompt emission phase, when the X-ray flux had already decayed by four orders of magnitude. Two possible explanations exist for the observed radiation: inverse Compton emission and synchrotron emission of ultrarelativistic electrons. Our observations show that the energy fluxes in the X-ray and γ-ray range and their photon indices remain comparable to each other throughout the afterglow. This discovery places distinct constraints on the GRB environment for both emission mechanisms, with the inverse Compton explanation alleviating the particle energy requirements for the emission observed at late times. The late timing of this detection has consequences for the future observations of GRBs at the highest energies

Neutrinos interact only very weakly with matter, but giant detectors have succeeded in detecting small numbers of astrophysical neutrinos. Aside from a diffuse background, only two individual sources have been identified: the Sun and a nearby supernova in 1987. A multiteam collaboration detected a high-energy neutrino event whose arrival direction was consistent with a known blazar—a type of quasar with a relativistic jet oriented directly along our line of sight. The blazar, TXS 0506+056, was found to be undergoing a gamma-ray flare, prompting an extensive multiwavelength campaign. Motivated by this discovery, the IceCube collaboration examined lower-energy neutrinos detected over the previous several years, finding an excess emission at the location of the blazar. Thus, blazars are a source of astrophysical neutrinos. Science , this issue p. 147 , p. eaat1378 A high-energy neutrino was emitted by a blazar during a flare, prompting observations across the electromagnetic spectrum. Previous detections of individual astrophysical sources of neutrinos are limited to the Sun and the supernova 1987A, whereas the origins of the diffuse flux of high-energy cosmic neutrinos remain unidentified. On 22 September 2017, we detected a high-energy neutrino, IceCube-170922A, with an energy of ~290 tera–electron volts. Its arrival direction was consistent with the location of a known γ-ray blazar, TXS 0506+056, observed to be in a flaring state. An extensive multiwavelength campaign followed, ranging from radio frequencies to γ-rays. These observations characterize the variability and energetics of the blazar and include the detection of TXS 0506+056 in very-high-energy γ-rays. This observation of a neutrino in spatial coincidence with a γ-ray–emitting blazar during an active phase suggests that blazars may be a source of high-energy neutrinos.

The origin of Galactic cosmic rays is a century-long puzzle. Indirect evidence points to their acceleration by supernova Shockwaves, but we know little of their escape from the shock and their evolution through the turbulent medium surrounding massive stars. Gamma rays can probe their spreading through the ambient gas and radiation fields. The Fermi Large Area Telescope (LAT) has observed the star-forming region of Cygnus X. The 1-to 100-gigaelectronvolt images reveal a 50-parsec-wide cocoon of freshly accelerated cosmic rays that flood the cavities carved by the stellar winds and ionization fronts from young stellar clusters. It provides an example to study the youth of cosmic rays in a superbubble environment before they merge into the older Galactic population.

Galactic cosmic rays reach energies of at least a few petaelectronvolts1 (of the order of 1015 electronvolts). This implies that our Galaxy contains petaelectronvolt accelerators (‘PeVatrons’), but all proposed models of Galactic cosmic-ray accelerators encounter difficulties at exactly these energies2. Dozens of Galactic accelerators capable of accelerating particles to energies of tens of teraelectronvolts (of the order of 1013 electronvolts) were inferred from recent γ-ray observations3. However, none of the currently known accelerators—not even the handful of shell-type supernova remnants commonly believed to supply most Galactic cosmic rays—has shown the characteristic tracers of petaelectronvolt particles, namely, power-law spectra of γ-rays extending without a cut-off or a spectral break to tens of teraelectronvolts4. Here we report deep γ-ray observations with arcminute angular resolution of the region surrounding the Galactic Centre, which show the expected tracer of the presence of petaelectronvolt protons within the central 10 parsecs of the Galaxy. We propose that the supermassive black hole Sagittarius A* is linked to this PeVatron. Sagittarius A* went through active phases in the past, as demonstrated by X-ray outbursts5and an outflow from the Galactic Centre6. Although its current rate of particle acceleration is not sufficient to provide a substantial contribution to Galactic cosmic rays, Sagittarius A* could have plausibly been more active over the last 106–107 years, and therefore should be considered as a viable alternative to supernova remnants as a source of petaelectronvolt Galactic cosmic rays.

We report on the 22 – 23 June 2015 geomagnetic storm that occurred at the summer solstice. There have been fewer intense geomagnetic storms during the current solar cycle, Solar Cycle 24, than in the previous cycle. This situation changed after mid-June 2015, when one of the largest solar active regions (AR 12371) of Solar Cycle 24 that was located close to the central meridian, produced several coronal mass ejections (CMEs) associated with M-class flares. The impact of these CMEs on the Earth’s magnetosphere resulted in a moderate to severe G4-class geomagnetic storm on 22 – 23 June 2015 and a G2 (moderate) geomagnetic storm on 24 June. The G4 solstice storm was the second largest (so far) geomagnetic storm of Cycle 24. We highlight the ground-level observations made with the New-Tupi, Muonca, and the CARPET El Leoncito cosmic-ray detectors that are located within the South Atlantic Anomaly (SAA) region. These observations are studied in correlation with data obtained by space-borne detectors (ACE, GOES, SDO, and SOHO) and other ground-based experiments. The CME designations are taken from the Computer Aided CME Tracking (CACTus) automated catalog. As expected, Forbush decreases (FD) associated with the passing CMEs were recorded by these detectors. We note a peculiar feature linked to a severe geomagnetic storm event. The 21 June 2015 CME 0091 (CACTus CME catalog number) was likely associated with the 22 June summer solstice FD event. The angular width of CME 0091 was very narrow and measured ∼ 56 ∘ degrees seen from Earth. In most cases, only CME halos and partial halos lead to severe geomagnetic storms. We perform a cross-check analysis of the FD events detected during the rise phase of Solar Cycle 24, the geomagnetic parameters, and the CACTus CME catalog. Our study suggests that narrow angular-width CMEs that erupt in a westward direction from the Sun–Earth line can lead to moderate and severe geomagnetic storms. We also report on the strong solar proton radiation storm that began on 21 June. We did not find a signal from this SEP at ground level. The details of these observations are presented.

The Large Magellanic Cloud, a satellite galaxy of the Milky Way, has been observed with the High Energy Stereoscopic System (H.E.S.S.) above an energy of 100 billion electron volts for a deep exposure of 210 hours. Three sources of different types were detected: the pulsar wind nebula of the most energetic pulsar known, N 157B; the radio-loud supernova remnant N 132D; and the largest nonthermal x-ray shell, the superbubble 30 Dor C. The unique object SN 1987A is, unexpectedly, not detected, which constrains the theoretical framework of particle acceleration in very young supernova remnants. These detections reveal the most energetic tip of a γ-ray source population in an external galaxy and provide via 30 Dor C the unambiguous detection of γ-ray emission from a superbubble.

The nearby radio galaxy Centaurus A belongs to a class of active galaxies that are luminous at radio wavelengths. Most show collimated relativistic outflows known as jets, which extend over hundreds of thousands of parsecs for the most powerful sources. Accretion of matter onto the central supermassive black hole is believed to fuel these jets and power their emission 1 . Synchrotron radiation from relativistic electrons causes the radio emission, and it has been suggested that the X-ray emission from Centaurus A also originates in electron synchrotron processes 2 – 4 . Another possible explanation is inverse Compton scattering with cosmic microwave background (CMB) soft photons 5 – 7 . Synchrotron radiation needs ultrarelativistic electrons (about 50 teraelectronvolts) and, given their short cooling times, requires some continuous re-acceleration mechanism 8 . Inverse Compton scattering, on the other hand, does not require very energetic electrons, but the jets must stay highly relativistic on large scales (exceeding 1 megaparsec). Some recent evidence disfavours inverse Compton-CMB models 9 – 12 , although other work seems to be compatible with them 13 , 14 . In principle, the detection of extended γ-ray emission, which directly probes the presence of ultrarelativistic electrons, could distinguish between these options. At gigaelectronvolt energies there is also an unusual spectral hardening 15 , 16 in Centaurus A that has not yet been explained. Here we report observations of Centaurus A at teraelectronvolt energies that resolve its large-scale jet. We interpret the data as evidence for the acceleration of ultrarelativistic electrons in the jet, and favour the synchrotron explanation for the X-rays. Given that this jet is not exceptional in terms of power, length or speed, it is possible that ultrarelativistic electrons are commonplace in the large-scale jets of radio-loud active galaxies. Observations of the radio galaxy Centaurus A at teraelectronvolt energies resolve its large-scale jet and favour electron synchrotron processes as the source of its X-ray emission.

The development of PET/MRI multimodality, requiring magnetic field immunity of the photodetectors associated with an increased demand for time-of-flight capabilities with a strong impact on effective PET sensitivity and image quality, has pushed the medical imaging community to progressively replace photomultipliers, traditionally used in PET scanners, by solid-state photodetectors, avalanche diodes (APD) and silicon photomultipliers (SiPM). Recent years have seen spectacular progresses in the performances of SiPMs, in terms of photodetection efficiency (PDE), noise and cross talk reduction, timing performance, etc., not mentioning their availability in a large variety of dimensions and packages, as single photodetectors, but also linear arrays and matrices of different sizes. As a result of this, SiPMs are progressively becoming the photodetectors of choice for a new generation of time-of-flight PET scanners (TOF-PET)

Positron annihilation line at 511 keV is a known component of the gamma-ray diffuse emission. It is believed to be produced in the Galaxy, but there could be possible extragalactic contribution as well. E.g., positrons can be produced in jets of active galactic nuclei (AGN) and after that accumulate and gradually annihilate in hot gaseous halos around galaxies. In this work we test this hypothesis in application to an individual object—the Andromeda galaxy (M31) which is close and has a supermassive black hole in its center, which powered an AGN before. We compute the growth history of the supermassive black hole in M31, relate it to the evolution of jet luminosity and estimate the positron content in its halo. We calculate the 511 keV photon flux due to positron annihilation which should be observed at Earth and find the value of around photon cm s . It is very close to the observational limits ( photon cm s ) set by the INTEGRAL/SPI in the assumption of the point source, so further observations would be able to constrain leptonic models of the jets and propagation of cosmic rays in the circumgalactic medium of large spiral galaxies.

Explosive astrophysical transients at cosmological distances can be used to place precision tests of the basic assumptions of relativity theory, such as Lorentz invariance, the photon zero-mass hypothesis, and the weak equivalence principle (WEP). Signatures of Lorentz invariance violations (LIV) include vacuum dispersion and vacuum birefringence. Sensitive searches for LIV using astrophysical sources such as gamma-ray bursts, active galactic nuclei, and pulsars are discussed. The most direct consequence of a nonzero photon rest mass is a frequency dependence in the velocity of light propagating in vacuum. A detailed representation of how to obtain a combined severe limit on the photon mass using fast radio bursts at different redshifts through the dispersion method is presented. The accuracy of the WEP has been well tested based on the Shapiro time delay of astrophysical messengers traveling through a gravitational field. Some caveats of Shapiro delay tests are discussed. In this article, we review and update the status of astrophysical tests of fundamental physics.