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\"Internet addiction is an emergent disorder in the psychiatric and psychological fields. This book provides a theoretical framework to understand how to define and conceptualize compulsive use of the Internet from a clinical perspective. With various theoretical models from the psychiatric, psychological, communication, and sociological fields, it explores the prevalence of the disorder and the most addictive or problematic online applications, such as online pornography, Internet gambling, and online games. Evidenced-based treatment approaches are provided as well. A must-have for every clinician\"--Provided by publisher.

Adolescents with Internet addiction (IA) frequently encounter elevated levels of anxiety and depression, which subsequently results in the perpetuation of their addiction behaviors. Mindfulness-based cognitive therapy for children (MBCT-C) is an adapted version of traditional MBCT that targets emotional problems in children. The present study aimed to provide a framework for the implementation of a clinical trial for its effectiveness in reducing anxiety, depression, and IA in adolescents with IA. This study protocol proposes a randomized controlled trial with two parallel arms (MBCT-C versus active control). Eighty Iranian adolescents (Persian ethnicity; males and females; 12 to 15 years) diagnosed with IA will be randomly assigned to the intervention group (12 sessions of MBCT-C group therapy) or the control group (12 life skills training sessions). Pre-intervention, post-intervention, and three-month follow-up assessments will be conducted using Mindful Attention Awareness Scale-Adolescents (MAAS-A), Mindfulness Program Satisfaction Questioner (MPSQ), Reynolds Adolescent Depression Scale (RADS), State-Trait Anxiety Inventory-Children (STAI-C), MBCT-C Adherence Scale (MBCT-C-AS), and Internet Addiction Test (IAT). Data will be analyzed using mixed regression model using STATA-18 to assess the effectiveness of MBCT-C. The current study has the potential to make a significant contribution to evaluate the effectiveness of MBCT-C to address IA, anxiety, and depression in adolescents with IA.

Research suggests that mindfulness-practices may aid smoking cessation. Yet, the neural mechanisms underlying the effects of mindfulness-practices on smoking are unclear. Response inhibition is a main deficit in addiction, is associated with relapse, and could therefore be a candidate target for mindfulness-based practices. The current study hence investigated the effects of a brief mindfulness-practice on response inhibition in smokers using behavioral and electroencephalography (EEG) measures. Fifty participants (33 females, mean age 20 years old) underwent a protocol of cigarette exposure to induce craving (cue-exposure) and were then randomly assigned to a group receiving mindfulness-instructions or control-instructions (for 15 minutes approximately). Immediately after this, they performed a smoking Go/NoGo task, while their brain activity was recorded. At the behavioral level, no group differences were observed. However, EEG analyses revealed a decrease in P3 amplitude during NoGo vs. Go trials in the mindfulness versus control group. The lower P3 amplitude might indicate less-effortful response inhibition after the mindfulness-practice, and suggest that enhanced response inhibition underlies observed positive effects of mindfulness on smoking behavior.

Mindfulness-based Tai Chi Chuan (MTCC) have been shown to contribute to improvements in cognitive and executive functions. Changes in inhibition, an aspect of executive function, have been closely linked to mobile phone addiction. However, the relationship between these elements remains unclear. This study aims to investigate the effects of an 8-week MTCC intervention on executive function, mindfulness levels, and mobile phone addiction in male college students. Additionally, the study explores the role of executive function in improving mobile phone addiction through MTCC interventions. Sixty-six male college students were selected as research subjects and randomly divided into a control group (33) and an experimental group (33). The control group maintained their normal physical activity levels without any additional intervention. In contrast, the experimental group underwent 8 weeks of MTCC training. Mindfulness levels were assessed using the Mindful Attention Awareness Scale (MAAS), while mobile phone addiction was evaluated by the Mobile Phone Addiction Index (MPAI). The Flanker task, 1-back task, and More-Odd Shifting task were employed to evaluate inhibition, updating, and shifting aspects of executive function, respectively. (1) The 8-week MTCC intervention significantly improved mobile phone addiction among male college students, with the intervention group showing a lower post-intervention MPAI score (46.09 ± 18.11) compared to the control group (56.55 ± 16.02), yielding a mean difference of -10.46 (95% CI: -18.92 to -1.99, p = 0.016). Mindfulness levels also improved significantly (p = 0.046), as did specific sub-functions of executive function: inhibition correct rate (p < 0.001), inhibition response (p = 0.001), and shifting correct rate (p = 0.001). No significant effects were observed for updating correct rate (p = 0.527) or updating response (p = 0.303). (2) Mobile phone addiction indices were significantly correlated with changes in inhibition response (r = 0.756, p = 0.000 < 0.01), updating response (r = 0.035, p = 0.045 < 0.05), and shifting response (r = 0.397, p = 0.022 < 0.05). (3) Mindfulness levels and inhibition levels were significantly correlated (r = 0.394, p = 0.023 < 0.05). (4) Changes in inhibition within executive functions partially mediated the improvement of mobile phone addiction, with the direct effect (0.716) and mediating effect (0.483) accounting for 59.72% and 40.28% of the total effect (1.199), respectively. MTCC exercises significantly increase cognitive functions, leading to increased inhibition and attentiveness, and may be helpful in the prevention of addictions, including cell phone addictions.

Rationale Chronic alcohol misuse can escalate into alcohol use disorder (AUD). The causal mechanisms through which recreational social drinking develops into compulsive uncontrolled alcohol misuse are multifaceted. For example, stress is an important risk factor that influences alcohol craving in both healthy and addicted individuals. In addition, those that are high in impulsivity/risk taking drink more and are at greater risk of developing addiction. At present, however, it is not possible accurately to predict those at risk of escalation in alcohol use, or of developing AUD. Objectives The aim of this study was to investigate how underlying physiological and personality traits affect stress-induced craving for, and consumption of, alcohol, in a sample of social drinkers. The primary hypothesis was that impulsivity/risk-taking would modulate stress-induced alcohol craving and consumption. Methods Thirty-nine participants (22 male and 17 female; mean age = 23.92 years [SD = 4.90]) were randomly allocated to ‘stress’ and ‘no-stress’ groups; in the stress group, participants took part in the Trier Social Stress Test (TSST). Participants completed several questionnaires and computer tasks in order to assess prior alcohol use, impulsivity/risk-taking, stress-reactivity, craving and physiological biomarkers of stress. Finally, participants completed a voluntary drinking task, in which increasing numbers of presses on a computer keyboard were reinforced with 5-ml shots of 37% ABV vodka (plus mixer). Results Participants exposed to the TSST showed an increase in craving following the stressor. Several factors predicted voluntary drinking, including risky decision making, slow HR recovery from stress, poor vagal tone during recovery from stress and greater stress reactivity. Surprisingly, we found no correlation between craving and consumption. Conclusions Our data suggest that variation in physiological stress parameters and poor decision-making abilities increase risk of stress-induced alcohol consumption. This may provide a useful translational framework through which we can further study early predictive markers for the shift between controlled recreational drinking to uncontrolled alcohol misuse, including AUD.

RationaleMinocycline, a tetracycline antibiotic, inhibits activation of microglia. In preclinical studies, minocycline prevented development of opioid tolerance and opioid-induced hyperalgesia (OIH). The goal of this study was to determine if minocycline changes pain threshold and tolerance in individuals with opioid use disorder who are maintained on agonist treatment.MethodsIn this double-blind, randomized human laboratory study, 20 participants were randomized to either minocycline (200 mg/day) or placebo treatment for 15 days. The study had three test sessions (days 1, 8, and 15 of treatment) and one follow-up visit 1 week after the end of treatment. In each test session, participants were assessed on several subjective and cognitive measures, followed by assessment of pain sensitivity using the Cold Pressor Test (CPT). Daily surveys and cognitive measures using Ecological Momentary Assessment (EMA) were also collected four times a day on days 8 through 14 of treatment, and proinflammatory serum cytokines were assessed before and on the last day of treatment.ResultsMinocycline treatment did not change pain threshold or tolerance on the CPT. Similarly, minocycline did not change severity of pain, opioid craving, withdrawal, or serum cytokines. Minocycline treatment increased accuracy on a Go/No-Go task.ConclusionsWhile these findings do not support minocycline’s effects on OIH, minocycline may have a potential use as a cognitive enhancer for individuals with opioid use disorder, a finding that warrants further systematic studies.

Food addiction is a controversial concept. The potential influence of food addiction on patients' psychosocial functioning and well-being has not been well established. The purpose of this study was to examine the relationships between psychosocial functioning (depressive symptoms and health-related quality of life [HRQOL]) and food addiction as measured by the Yale Food Addiction Scale (YFAS). We also explored whether food addiction contributed additional variance in explaining psychosocial functioning, beyond demographic and clinical factors (e.g., binge eating). The sample included 178 participants (mean age=44.2±11.2years; BMI=40.9±5.9kg/m2; 88.2% female; 70.8% Black) with obesity seeking treatment for weight loss. Participants completed the Medical Outcomes Study 36-Item Short-Form Health Survey, Impact of Weight on Quality of Life-Lite, Patient Health Questionnaire, YFAS, and Questionnaire on Eating and Weight Patterns-5. Twelve (6.7%) participants met criteria for food addiction, with 4 (33.3%) of these participants having co-occurring binge eating disorder. After adjusting for covariates, the number of food addiction symptoms accounted for 6.5% to 16.3% of additional variance in general HRQOL, 5.0% to 21.5% in weight-related HRQOL, and 19.1% in symptoms of depression. In this treatment-seeking sample of participants, we found a low prevalence of food addiction, suggesting that addictive-like eating is unlikely to be a causal mechanism for most people with obesity. However, individuals who met criteria for food addiction had reduced psychosocial functioning compared to those who did not meet criteria. Individuals with addictive-like eating may require additional psychosocial support.

Objective Mobile phone addiction has become increasingly severe among college students, adversely affecting their physical and mental health as well as academic performance. Although physical activity (PA) interventions have been shown to alleviate mobile phone addiction, existing research mostly focuses on single-form exercises and lacks in-depth exploration of underlying mechanisms. Therefore, this study aims to examine the effectiveness of a combined intervention involving badminton and fancy rope skipping on improving mobile phone addiction in college students, and further analyze the chain mediating roles of emotion regulation strategies and positive coping styles. Methods This study adopted a pretest-posttest quasi-experimental design. A cohort of 195 college students meeting DSM-V diagnostic criteria for mobile phone addiction were enrolled and randomly allocated to one of three groups: a combined intervention group ( n  = 74), a badminton intervention group ( n  = 62), and a control group ( n  = 59). The intervention groups engaged in a 12-week exercise program, 5 sessions per week, each lasting 45 min, while the control group maintained their usual lifestyle. The Mobile Phone Addiction Index (MPAI; Leung) was used to assess mobile phone addiction levels before and after the intervention, while the Emotion Regulation Questionnaire (ERQ; Gross & John) and Simplified Coping Style Questionnaire (SCSQ; Yaning Xie) were used to measure emotion regulation strategies and positive coping styles, respectively. SPSS 27.0 software was utilized to conduct one - way ANOVA, chi - square tests, simple effect analysis, etc. The PROCESS 4.2 macro program was employed to perform chain mediation effect analysis of emotion regulation strategies and positive coping styles. The statistical significance level was set at P  ≤ 0.05. Results The combined intervention group showed significant improvements ( P  < 0.05) in all dimensions of mobile phone addiction—withdrawal, loss of control, inefficiency, and escapism—as well as in total scores, outperforming both the badminton-only and control groups. Emotion regulation strategies and positive coping styles were found to play partial chain mediating roles in the relationship between PA intervention and improvements in mobile phone addiction. The total indirect effect (0.689) accounted for 77.94% of the total effect (0.884). Path analysis further revealed that the intervention indirectly reduced addictive behaviors by first improving emotion regulation strategies, followed by enhancing positive coping. Conclusion Compared with single-form exercise, combined PA is more effective in alleviating mobile phone addiction among college students, primarily through the chain mediating effects of improved emotion regulation strategies and enhanced positive coping styles. It is recommended that universities and relevant institutions promote combined physical activities to help college students reduce mobile phone addiction and improve their overall well - being.

There is an ongoing debate about whether buying-shopping disorder (BSD) should be acknowledged as a behavioral addiction. The current study investigated if mechanisms that play a prominent role in disorders due to substance use or addictive behaviors are relevant in BSD, particularly cue reactivity, craving, cognitive bias and reduced inhibitory control regarding addiction-relevant cues. The study included 39 treatment-seeking patients with BSD and 39 healthy control (HC) participants (29 women and 10 men in each group). Subjective responses toward buying/shopping-relevant visual cues were compared in patients vs. control participants. Experimental paradigms with neutral and semi-individualized buying/shopping-related pictures were administered to assess attentional bias, implicit associations and response inhibition with respect to different visual cues: Dot-probe paradigm (DPP), Implicit Association Task (IAT), Go/nogo-task (GNG). The severity of BSD, craving for buying/shopping, and symptoms of comorbid mental disorders (anxiety, depressive and hoarding disorders) were measured using standardized questionnaires. The BSD-group showed more general craving for buying/shopping, stronger subjective craving reactions towards buying/shopping-related visual cues, and more symptoms of anxiety, depression and hoarding disorder than control participants. Task performance in the DPP, IAT and GNG paradigm did not differ between the two groups. The present findings confirm previous research concerning the crucial role of craving in BSD. The assumption that attentional bias, implicit associations and deficient inhibitory control with respect to buying/shopping-related cues are relevant in BSD could not be proven. Future research should address methodological shortcomings and investigate the impact of acute psychosocial stress and present mood on craving responses, cognitive processing, and response inhibition in patients with BSD.