Explore the vast range of titles available.

Evidence for open groin hernia repair demonstrates less pain with bioglue mesh fixation compared with invasive methods. This study aimed to assess the short- and long-term effects of laparoscopic groin hernia repair with noninvasive and invasive mesh fixation. A systematic review of MEDLINE, CENTRAL, and OpenGrey was undertaken. Randomized trials assessing the outcome of laparoscopic groin hernia repair with invasive and noninvasive fixation methods were considered for data synthesis. Nine trials encompassing 1,454 patients subjected to laparoscopic hernia repair with mesh fixation using biologic or biosynthetic glue were identified. Short-term data were inadequate for data synthesis. Chronic pain was less frequently reported by patients subjected to repair with biologic glue fixation than with penetrating methods (odds ratio .46, 95% confidence interval .22 to .93). Duration of surgery, incidence of seroma/hematoma, morbidity, and recurrence were similar. Laparoscopic groin hernia repair with bioglue mesh fixation was associated with a reduced incidence of chronic pain compared with mechanical fixation, without increasing morbidity or recurrence. Longer term data on recurrence are necessary. •Bioglue has recently emerged as an alternative means of mesh fixation in open and laparoscopic groin hernia repair.•Synthesis of data suggests that this method reduces chronic postoperative pain, without increasing morbidity or recurrence.•Longer term data on recurrence are needed.

Cyanoacrylate injection is widely used to treat hemorrhagic gastric varices. A pulmonary glue embolism is an unusual but potentially fatal complication. We present a case of a 51-year-old man with a history of alcoholic hepatic cirrhosis Child-Pugh B, who had an acute pulmonary embolism with sudden cardiorespiratory collapse due to biological glue injection used for the emergent repair of bleeding gastric varices. After the restoration of respiratory and hemodynamic parameters, he was admitted to the intensive care unit and the pulmonary biological glue emboli were documented with computed tomography scan. A high index of suspicion for this entity is essential in patients submitted to endoscopic sclerotherapy. Some might be asymptomatic or mildly symptomatic, while others might present with cardiorespiratory collapse.

Mine ramps, serving as a critical transportation hub in underground mining activities, are beset by severe issues of dust pollution and secondary dust generation. While dust suppressants are more efficient than the commonly used sprinkling methods in mines, traditional single-function dust suppressants are inadequate for the complex application environment of mine ramps. Building on the development of conventional single-function dust suppressants, this research optimized the components of bonding, wetting, and moisturizing agents. Through single-factor optimization experiments, a comparison was made of the surface tension water retention property and viscosity of diverse materials, thus enabling the identification of the primary components of the dust suppressant. By means of synergistic antagonism experiments, the optimal combination of the wetting agent and bonding agent with excellent synergy was ascertained. Ultimately, the wind erosion resistance and rolling resistance were measured through three-factor orthogonal experiments, and the optimal ratio of the dust suppressant was established. Specifically, fenugreek gum (FG) was selected as the bonding agent, cane sugar (CS) as the moisturizing agent, and alkyl phenol polyoxyethylene ether (Op-10) as the wetting agent. The research findings demonstrate that the optimal ratio of dust suppressant is 0.3 wt% fenugreek gum (FG) + 0.06 wt% alkyl phenol polyoxyethylene ether (Op-10) + 3 wt% cane sugar (CS). Under these conditions, the dust fixation rate can reach up to 97~98% at a wind speed of 8 m/s. The maximum rolling resistance can reach 65~73% after grinding the samples for 1 min. The surface tension of the solution is 13.74 mN/m, and the wetting performance improved by 81% compared to pure water. This dust suppressant is of great significance for improving the working environment of workers and ensuring the sustainable development of the mining industry.

Single-walled carbon nanotube (SWNT) has gained significant interest as a transducer in various electrochemical sensing devices due to their unique structure, compatibility with biomolecules, and excellent electronic properties. As-prepared SWNTs are usually a mixture of semiconducting and metallic ones. Despite of the higher content of semiconducting components in mixed SWNTs, metallic properties are predominantly expressed due to the bundling issue of the SWNT during the fabrication process, limiting the applicability to bio-transistor application. Here, we present a multi-scale semiconducting electronic film of SWNTs as a transducing platform for electrochemical field-effect-transistor (eFET) suitable for the sensitive detection of subtle biological modulation. A genetically engineered filamentous M13 phage showing strong binding affinity toward SWNTs on its body surface was used as a biological material, allowing us to fabricate a large-scale transparent semiconducting nanocomposite. As the relative ratio of SWNT to M13 phage decreases, the on–off ratio of SWNT electronic film increases by 1200%. To show broad applicability, the multi-scale SWNT nanomesh-based eFET is applied for monitoring a variety of biological reactions in association with enzymes, aptamers, and even cyanobacteria. The biomimetic electronic material system with the capability of transducing biological responses at a large scale over a broad dynamic range holds excellent promise for biosensors, biofuel cells, and environment monitoring.

Background Various types of medical glues/adhesives/topical coagulants’ (referred to as MG hereinafter) have widespread application as surgical adhesives, and have been shown to be safe and effective for a broad range of usage, such as in hemostasis, reinforcement of intestinal anastomoses or sites of potential fluid leakage, adhesion of two surfaces, wound closure, and vascular embolization. However, inappropriate application of MG may sometimes lead to serious complications. Herein, we describe three cases of serious postoperative complications induced by a possible inappropriate use of N-butyl-2-cyanoacrylate MG (NBCA MG). Case presentation Three patients presented with abdominal pain (chronic pain in cases 1 and 2, and acute pain in Case 3), hematochezia (Case 2), and intestinal obstruction (Case 3). All patients had a history of abdominal surgery and intraoperative use of NBCA MG. Abdominal computed tomography and gastroenterological endoscopy revealed foreign bodies (solidified MG in cases 1 and 2) and intestinal obstruction related to a mass of residual non-absorbed MG causing an internal hernia from a dense adhesion (Case 3). All patients underwent exploratory laparotomy, which revealed duodenal perforation, colonic erosion, and an internal hernia, all of which was related to MG use. We undertook removal of the foreign bodies (cases 1 and 2), surgical closure of the site of duodenal erosion (Case 1), partial colectomy (Case 2), and partial enterectomy (Case 3). Conclusion Inappropriate application of MG may induce serious complications. We emphasize the importance of careful evaluation of the indications, dosage, and spraying thickness of MG in clinical practice. Serious complications caused by inappropriate application of MG should be reported to raise awareness in the surgical fraternity.

[2] Invasive species or non-indigenous species are that organism which are non-native to the environment and have negative effects on the respective regions economy, public health, etc. According to IMO study CO2 has been released as 769 Million tons in 2014 and by 2050 there will be a risk for its increase by 50-250% which will further lead to increase in greenhouse gas emissions and result in global warming. The UN Convention on the Law of the Sea (UNCLOS) provides a global framework by requiring States for the work together \"To prevent intentional or accidental introduction of alien species to particular part of marine environment.\" Whenever some clean material surface is immersed in the water, then a sheath of dissolved organic materials develops on the material surface leading to the adsorption of the colonized bacteria getting adhered and travel [19] Once these species are established in a particular environment it becomes very tough to get rid from them.

This study was designed to evaluate the efficacy and safety of CT-guided embolization of internal iliac artery aneurysm (IIAA) after repair of abdominal aortic aneurysm by transretroperitoneal approach using the lidocaine injection technique to iliacus muscle, making window for safe needle path for three patients for whom CT-guided embolization of IIAA was performed by transretroperitoneal approach with intramuscular lidocaine injection technique. Transretroperitoneal access to the IIAA was successful in all three patients. In all three patients, the IIAA was first embolized using microcoils. The aneurysmal sac was then embolized with glue and coils without complication. With a mean follow-up of 7 months, the volume of the IIAAs remained stable without residual endoleaks. Transretroperitoneal CT-guided embolization of IIAA using intramuscular lidocaine injection technique is effective, safe, and results in good outcome.

Adequate repair of cerebrospinal fluid leak remains a significant challenge in endoscopic skull base surgery. Laser tissue welding (LTW) is a method of creating an instant watertight wound closure using a chromophore doped biological solder, which may be used for cranial base reconstruction. The objective of this study is to assess the safety and technical feasibility of endoscopic LTW in human sinonasal mucosa. A prospective, Institutional Review Board-approved study was performed of 10 patients undergoing endoscopic LTW using an albumin and hyaluronic acid-based solder for repair of mucosal injuries. Data were collected on patient demographics, total lasing time, and volume of solder used. Wounds were prospectively followed by endoscopic exam and scored on a scale of zero to two by three blinded observers (B.S.B., J.N.P., and A.G.C.) for inflammation, thermal injury, and edema. Results were compared with control wounds using the Mann-Whitney U test. Ten patients (seven men and three women; average age 50 years; range, 33-71 years) underwent endoscopic LTW. Total lasing time was 11 +/- 11 minutes requiring 0.96 +/- 0.83 mL of solder per patient. Patients were followed for an average of 72 days (range, 12-138 days) and no complications were noted. Solder persisted for up to 26 days and there was no significant difference between the lased and control wounds with regard to inflammation (0.87 +/- 0.72 versus 1.31 +/- 0.87), thermal injury (0.06 +/- 0.25 versus 0.12 +/- 0.34), or edema scores (1.13 +/- 0.81 versus 1.44 +/- 0.73). Endoscopic LTW is a technically feasible and rapid method of wound closure in sinonasal mucosa that does not result in any significant thermal or inflammatory sequelae.

Background The aim of the study was to compare the degree of healing and air tightness of hand-sewn colonic anastomoses provided by different biological glues. Methods Thirty colonic anastomoses were fashioned in ten rabbits, at 5, 10, 15 cm from the ileocecal valve, with 4/0 PDS running sutures. Each suture was randomized to treatment with fibrin sealant (Tissucol ® ), a synthetic glue (Coseal ® ), or nothing (control). After 15 days, the rabbits were killed and the anastomoses examined for their integrity and resistance to bursting. The van der Hamm scale was used to evaluate postoperative adhesions. A blind histological evaluation of the newly formed tissue was made (Ehrlich–Hunt scale). Results Two rabbits developed an intraabdominal abscess, one in the control anastomosis group without glue. Postoperative adhesions were present in all animals. Median anastomosis bursting pressures were 0.9 atm in all three groups: Tissucol, Coseal, and control. Pressure values were 0.9, 1.0, and 0.9 atm in the three different proximodistal sites, respectively. A trend toward an increased resistance was observed in the glued anastomosis, although this was not significant. Lymphocyte infiltration, fibroblast activity, blood vessel density, and collagen deposition were lower in controls. Anastomoses treated with Tissucol had the highest lymphocyte infiltration level. The Coseal group developed the highest rates of fibroblast activity, collagen deposition, and blood vessel neogenesis. Conclusion The use of biological glues did not result in a statistically significantly increased bursting resistance. Histological evaluation demonstrated more intense tissue neoformation in the glue groups, particularly in the Coseal group. The role of biological glues in decreasing the leakage rate of intestinal anastomoses is uncertain, and larger trials using different protective agents are warranted.