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Biopharmaceutical benchmarks 2014
Monoclonal antibodies continue their march on the markets, optimized so-called biobetter versions of existing biologics are also gaining ground, but the rate of biosimilar approvals has seen a dramatic slowdown in recent years.
Journal Article
Enabling Microfluidics: from Clean Rooms to Makerspaces
The traditional requirement for clean rooms and specialized skills has inhibited many biologists from pursuing new microfluidic innovations. Makerspaces provide a growing alternative to clean rooms: they provide low-cost access to fabrication equipment such as laser cutters, plotter cutters, and 3D printers; use commercially available materials; and attract a diverse community of product designers. This Opinion discusses the materials, tools, and building methodologies particularly suited for developing novel microfluidic devices in these spaces, with insight into biological applications and leveraging the maker community. The lower barrier to access of makerspaces ameliorates the otherwise poor accessibility and scalability of microfluidic prototyping.
The use of simple tools and materials to manufacture microfluidic devices provides an opportunity for makerspaces to serve as a hotbed for microfluidic device development.
Materials such as plastic, adhesive, and paper, along with tools such as plotter/laser cutters and 3D printers, enable building integrated microfluidic systems that are more easily translated to large-scale manufacturing.
Makerspaces provide low-cost access to prototyping tools and access to technically diverse human capital, and they enable those without advanced skills to participate in microfluidic device development.
Journal Article
Navigating B2B and B2C business models in biotechnology
Commercialising biotechnology innovations relies on selecting an appropriate business model. This article explores the nuances of the business-to-business and business-to-consumer pathways, highlighting key considerations for selecting the best model. It aims to provide entrepreneurs and stakeholders with actionable insights for navigating the biotech industry’s dynamic landscape.
Commercialising biotechnology innovations relies on selecting an appropriate business model. This article explores the nuances of the business-to-business and business-to-consumer pathways, highlighting key considerations for selecting the best model. It aims to provide entrepreneurs and stakeholders with actionable insights for navigating the biotech industry’s dynamic landscape.
Journal Article
From academia to real-life biotech: ‘It takes a village’
Here, we describe a workshop that analyzed synthetic biology at the academia–industry interface. We discuss how research can mature into successful biotech ventures and the infrastructure to support the transfer. We conclude that ‘it takes a village’: all components are necessary and must collaborate to grow academic ideas into real-life technologies.
Here, we describe a workshop that analyzed synthetic biology at the academia–industry interface. We discuss how research can mature into successful biotech ventures and the infrastructure to support the transfer. We conclude that ‘it takes a village’: all components are necessary and must collaborate to grow academic ideas into real-life technologies.
Journal Article
Portfolio, program, and project management in the pharmaceutical and biotechnology industries
This book describes the way that pharmaceutical projects and programs are currently managed, and offers views from many highly experienced practitioners from within the industry on future directions for drug program management. The book integrates portfolio, program, and project management processes as fundamental for effective and efficient drug product development. Contributing expert authors provide their view of how the projectization approach can be taken forward by the drug industry over the coming years.
eBook
UFSC Biotech Network: a transdisciplinary platform for biotechnology innovation in Brazil
Biotech Network (Rede Biotech in Portuguese) is a crossdisciplinary initiative launched at the Federal University of Santa Catarina (UFSC) to foster innovative biotechnological solutions aligned with Brazil’s scientific, environmental, and societal challenges. Here, we highlight the structure, mission, and pioneering research efforts of the network, offering a model for integrated and sustainable biotechnology development in emerging economies.
Biotech Network (Rede Biotech in Portuguese) is a crossdisciplinary initiative launched at the Federal University of Santa Catarina (UFSC) to foster innovative biotechnological solutions aligned with Brazil’s scientific, environmental, and societal challenges. Here, we highlight the structure, mission, and pioneering research efforts of the network, offering a model for integrated and sustainable biotechnology development in emerging economies.
Journal Article
Building outside of the box: iGEM and the BioBricks Foundation
Innovative community efforts in academia and non-profits to engage student researchers, encourage open sharing of DNA constructs and new methodology as well as build a Registry of Standardized Biological Parts have been central to the emergence of synthetic biology.
Journal Article
Behind Cuba's successful pandemic response
On the basis of as-yet-unpublished results from early-stage clinical trials, Vicente Verez-Bencomo, director-general of the Finlay Institute, expects the vaccine to show an efficacy in the region of 80–95%. “The international health programme is about solidarity; Cuba believes that healthy populations are the bedrock of global society and they want to support that any way they can”, said Clare Wenham, assistant professor of global health policy at the London School of Economics and Political Science (London, UK). “Health centres and clinics face regular stock outs of basic drugs, such as paracetamol, and other equipment such as bandages”, notes Fiona Samuels, senior research fellow and honorary associate professor at the London School of Hygiene & Tropical Medicine (London, UK).
Journal Article