Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
5,783
result(s) for
"Brain Pathophysiology."
Sort by:
Plasticity and Pathology: On the Formation of the Neural Subject
This collection of essays explores the historical and theoretical dimensions of the contemporary neural subject. With a multidisciplinary perspective, the volume focuses attention on the important, but problematic notion of plasticity as a way of rethinking the relationship between human experience and both pathological and normal states of the nervous system.
eBook
Broken brains
\"Drawing on real life examples and anecdotes from neurosurgery and neurobiology, this engaging introduction to brain function and dysfunction is ideal for those interested in learning more about the brain in an accessible way. Ian Mitchell brings biological psychology to life with examples of real life applications of the theory\"-- Provided by publisher.
Book
Speech and language disorders associated with subcortical pathology
This book provides comprehensive coverage of speech and language disorders arising from pathological processes involving the subcortical structures of the brain. It gives an understanding of these disorders in terms of their neuropathological basis, clinical symptomatology and prognosis. A full discussion of contemporary models and theories of subcortical participation in speech and language processing is given, including discussion of the possible roles of structures such as the basal ganglia, subthalamic nucleus, thalamus and cerebellum.
The book covers speech and language disorders associated with a variety of subcortical conditions, ranging from major degenerative conditions such as Parkinsons' Disease, Huntington's chorea and dystonia, through to acquired non-degenerative subcortical lesions arising from, for example, cerebrovascular accidents and sterotactic surgically induced lesions. In addition, a full description of the relevant assessment and treatment procedures currently recommended for use for each of the subcortical communication disorders is given.
eBook
Change your brain, change your life : the breakthrough program for conquering anxiety, depression, obsessiveness, lack of focus, anger, and memory problems
\"You're not stuck with the brain you're born with. Renowned neuropsychiatrist Dr. Daniel Amen includes cutting-edge reseach and the latest surprising, effective 'brain prescriptions' that can help heal your brain and change your life.\" -- Provided by publisher.
Book
Eating disorders and the brain
Why is the brain important in eating disorders? This ground-breaking new book describes how increasingly sophisticated neuroscientific approaches are revealing much about the role of the brain in eating disorders. Even more importantly, it discusses how underlying brain abnormalities and dysfunction may contribute to the development and help in the treatment of these serious disorders.
* Neuropsychological studies show impairments in specific cognitive functions, especially executive and visuo-spatial skills.
* Neuroimaging studies show structural and functional abnormalities, including cortical atrophy and neural circuit abnormalities, the latter appearing to be playing a major part in the development of anorexia nervosa.
* Neurochemistry studies show dysregulation within neurotransmitter systems, with effects upon the modulation of feeding, mood, anxiety, neuroendocrine control, metabolic rate, sympathetic tone and temperature.
The first chapter, by an eating disorders clinician, explains the importance of a neuroscience perspective for clinicians. This is followed by an overview of the common eating disorders, then chapters on what we know of them from studies of neuroimaging, neuropsychology and neurochemistry. The mysterious phenomenon of body image disturbance is then described and explained from a neuroscience perspective. The next two chapters focus on neuroscience models of eating disorders, the first offering an overview and the second a new and comprehensive explanatory model of anorexia nervosa. The following two chapters offer a clinical perspective, with attention on the implications of a neuroscience perspective for patients and their families, the second providing details of clinical applications of neuroscience understanding. The final chapter looks to the future.
This book succinctly reviews current knowledge about all these aspects of eating disorder neuroscience and explores the implications for treatment. It will be of great interest to all clinicians (psychiatrists, psychologists, nurses, dieticians, paediatricians, physicians, physiotherapists) working in eating disorders, as well as to neuroscience researchers.
eBook
Metal-based neurodegeneration : from molecular mechanisms to therapeutic strategies
Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies.
Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scientific findings, including details of their biochemical actors (proteins or peptides), their normal and pathological conformations, and a description of the diseases characteristics, with an emphasis on the role of metal-induced oxidative stress, which can result in the production of intracellular aggregates of target proteins and peptides.
Topics covered include:
* Brain function, physiology and the blood-brain barrier
* Immune system and neuroinflammation
* Aging and mild cognitive impairment, MCI
* Parkinson's Disease
* Alzheimer's Disease
* Creutzfelt-Jakob and related prion diseases
* Alcoholic Brain Damage
* Therapeutic strategies to combat the onset and progression of neurological diseases
This extensively updated, full colour, second edition of Metal-based Neurodegeneration is an essential text for research scientists and clinicians working in gerontology, neuropathology, neurochemistry, and metalloprotein mechanisms.
eBook
The patient's brain : the neuroscience behind the doctor-patient relationship
Due to advances within neuroscience, we are now in a much better position to be able to describe and discuss the biological mechanisms that underlie the doctor-patient relationship. Using this knowlege, this book describes and demonstrates the power that the doctor's behaviour has on a patient's behaviour and capacity for recovery from illness.
eBook
Blood-Based Biomarkers for Traumatic Brain Injury: A New Era in Diagnosis and Prognosis
Traumatic brain injury (TBI) is a major global health concern and a leading cause of mortality and disability. Head computed tomography (CT) remains indispensable for the detection of intracranial hemorrhage; however, its indiscriminate use in mild trauma increases radiation exposure, cumulative oncogenic risk, and healthcare costs. Consequently, there is growing interest in tools capable of improving sensitivity in mild or early-stage TBI. Protein-based biomarkers are promising complements to conventional assessment. Molecules such as glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase L1 (UCH-L1), S100 calcium-binding protein B (S100B), and neurofilament light chain (NfL) reflect astroglial activation, neuronal injury, and axonal damage, enabling objective evaluation of neurotrauma. Beyond protein biomarkers, metabolomic and lipidomic approaches capture alterations associated with early metabolic distress, oxidative stress, mitochondrial dysfunction, and membrane disruption following TBI. High-resolution mass spectrometry studies have identified reproducible metabolite and lipid signatures correlating with injury severity and functional outcomes. Longitudinal profiling further reveals dynamic metabolic trajectories that distinguish secondary injury progression from stabilization, supporting predictive modeling and risk stratification. Together, these advances pave the way toward precision medicine in neurotrauma. Nevertheless, variability in assay performance and sampling timing continues to limit widespread clinical adoption. Future research should prioritize methodological standardization, analytical validation, and the integration of multi-omic data with machine learning–based predictive models.
Journal Article
Behavioral Neurology & Neuropsychiatry
The merger of behavioral neurology and neuropsychiatry into a single medical subspecialty, Behavioral Neurology & Neuropsychiatry, requires an understanding of brain-behavior relationships and a clinical approach that transcends the traditional perspectives of neurology and psychiatry. Designed as a primer of concepts and principles, and authored by a multidisciplinary group of internationally known clinical neuroscientists, this book divides into three sections: • Structural and Functional Neuroanatomy (Section I) addresses the neuroanatomy and phenomenology of cognition, emotion, and behavior • Clinical Assessment (Section II) describes neuropsychiatric history taking, neurological and mental status examinations, neuropsychological assessment, and neuroimaging, electrophysiologic, and laboratory methods • Treatment (Section III) discusses environmental, behavioral, rehabilitative, psychological, social, pharmacological, and procedural interventions for cognitive, emotional, and behavioral disorders. By emphasizing the principles of Behavioral Neurology & Neuropsychiatry, this book will improve your understanding of brain-behavior relationships and inform your care of patients and families affected by neurobehavioral disorders.
eBook