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No detailed description available for \"We Came Naked and Barefoot\".

\"Laila Lalami brings us the imagined memoirs of the first black explorer of America--a Moroccan slave whose testimony was left out of the official record.\"--Amazon.com

This book is one of the great first-person accounts of the Spanish conquest of the Americas in the sixteenth century. Morrow’s new translation makes Cabeza deVaca’s adventures available to a wide English-speaking audience for the first time.

Map generalization is a process of producing maps at different levels of detail by retaining essential properties of the underlying geographic space. In this article, we explore how the map generalization process can be guided by the underlying scaling of geographic space. The scaling of geographic space refers to the fact that in a geographic space, small things are far more common than large ones. In the corresponding rank-size distribution, this scaling property is characterized by a heavy-tailed plot such as a power law, lognormal, or exponential function. In essence, any heavy-tailed distribution consists of the head of the distribution (with a low percentage of vital or large things) and the tail of the distribution (with a high percentage of trivial or small things). Importantly, the low and high percentages constitute an imbalanced contrast, e.g., 20 versus 80. We suggest that the purpose of map generalization is to retain the objects in the head and to eliminate or aggregate those in the tail. We applied this selection rule to three generalization experiments and found that the scaling of geographic space indeed underlies map generalization. We further relate the universal rule to Töpfer's radical law (or trained cartographers' decision making in general) and illustrate several advantages of the universal rule.

Using an appropriate trap design can significantly increase trap capture rates for specific insect pests. Chrysobothris are common buprestid pests in nursery production. Using traps that are shaped to mimic preferred tree hosts captured higher numbers of Chrysobothris than other trap designs. Based on these tests, the best trap design (shape and materials) for Chrysobothris monitoring was clear glue on a purple plastic trap folded into a triangular prism shape with panel widths (i.e., 3.8 cm) and trap height (i.e., 1 m) similar to a young sapling tree trunk. Our trap design will help in Chrysobothris pest management strategies for tree nurseries by increasing capture success rates and leading to overall better monitoring of Chrysobothris populations in nursery production. El uso de un diseño de trampa apropiado puede aumentar significativamente la tasa de captura de las trampas para plagas de insectos específicos. Chrysobothris son plagas bupréstidas comunes en viveros en producción. El uso de trampas que imitan la forma de los árboles hospederos preferidos capturó un mayor número de Chrysobothris que otros diseños de trampas. Con base en estas pruebas, el mejor diseño de trampa (forma y materiales) para el monitoreo de Chrysobothris fue pegamento transparente en una trampa de plástico púrpura doblada en forma de prisma triangular con el ancho de los paneles (3,8 cm) y su altura (1 m) similares a un tronco de árbol joven. Nuestro diseño de trampa ayudará en las estrategias de manejo de plagas de Chrysobothris en los viveros de árboles al aumentar la tasa de éxito de captura y llegar a un mejor monitoreo general de las poblaciones de Chrysobothris en la producción en viveros.

As a component of the ubiquitin ligase complex, Cullin 4B (CUL4B) is involved in the process of ubiquitination of different substrates, controlling genome stability, nucleotide excision repair, and chromatin-remodeling. The mutations in the CUL4B gene are revealed to be a cause of Cabezas syndrome (OMIM 300354), a rare syndromic form of X-linked intellectual disability (XLID). In this study, whole-exome sequencing analysis and Sanger sequencing identified two maternally inherited likely pathogenetic variants ( CUL4B , NM_001079872.2: c.803dupT/p. Leu268fs*5; c.953_957delTTATA/p. Ile318fs*2) in two probands, respectively. Patients carrying CUL4B variants presented with broad and variable phenotypic defects. The clinical manifestations of the two boys are consistent with Cabezas syndrome; however, they exhibit significant heterogeneity compared to previously reported cases. Phenotypic manifestations resulting from genetic variations may exhibit population differences and, in some cases, may present with concealed or latent expressions. Therefore, regular pediatric health check-ups and appropriate molecular diagnostic techniques are essential for the early detection, diagnosis, and treatment of such disorders. Our findings could be used to better define the genetic map in this area and will be valuable in the genetic diagnosis of the disease.

Objectives: Examine the effects of Kinesiology Taping (KT) on head and trunk control in children diagnosed with Duchenne muscular dystrophy (DMD). Design: A randomized controlled trial. Settings: Outpatient Clinics, Physical Therapy faculty, Benha University, Egypt. Subjects: forty-eighth children diagnosed with DMD, aged 8 to 12 years. Intervention: Children were equally (n = 24/group) assigned to two groups in a random manner. The study group received KT applied to the head and trunk extensors in conjunction with the traditional physical therapy (TPT) program over 8 weeks. The control group underwent only the TPT program for the same duration. Main measures: The primary outcomes included H-reflex latency and amplitude, which were assessed using an electromyography device for the levator scapulae and iliocostalis lumborum muscles. Additionally, the Pediatric Quality of Life Inventory (PedsQL) Multidimensional Fatigue Scale (MFS) was utilized for both the children and their parents, with data collected at baseline and following the intervention. Results: The results revealed significant differences in the levator scapulae and iliocostalis lumborum muscles after an eight-week intervention period, with the study group demonstrating greater changes than the control. Additionally, comparisons of PedsQL and MFS scores before and after the intervention showed significant improvements. Conclusions: KT can improve head and trunk control in DMD patients. Objetivos: Examinar los efectos del vendaje neuromuscular (Kinesiology Taping, KT) sobre el control de la cabeza y el tronco en niños diagnosticados con distrofia muscular de Duchenne (DMD). Diseño: Ensayo controlado aleatorizado. Entorno: Clínicas ambulatorias, Facultad de Fisioterapia, Universidad de Benha, Egipto. Sujetos: Cuarenta y ocho niños diagnosticados con DMD, con edades comprendidas entre 8 y 12 años. Intervención: Los niños fueron asignados aleatoriamente en dos grupos iguales (n = 24 por grupo). El grupo experimental recibió KT aplicado a los músculos extensores de la cabeza y el tronco junto con el programa tradicional de fisioterapia (TPT) durante 8 semanas. El grupo de control realizó únicamente el programa TPT durante el mismo período. Medidas principales: Las variables primarias incluyeron la latencia y la amplitud del reflejo H, evaluadas mediante un dispositivo de electromiografía en los músculos elevador de la escápula e iliocostal lumbar. Además, se utilizó la Escala Multidimensional de Fatiga (MFS) del Inventario de Calidad de Vida Pediátrica (PedsQL) tanto para los niños como para sus padres, con datos recogidos al inicio y después de la intervención. Resultados: Los resultados mostraron diferencias significativas en los músculos elevador de la escápula e iliocostal lumbar después de un período de intervención de ocho semanas, con mayores cambios en el grupo experimental en comparación con el grupo de control. Asimismo, la comparación de las puntuaciones del PedsQL y del MFS antes y después de la intervención mostró mejoras significativas. Conclusiones: El vendaje neuromuscular (KT) puede mejorar el control de la cabeza y el tronco en pacientes con DMD. Objectivos: Examinar os efeitos da ligadura neuromuscular (BNM) no controlo da cabeça e do tronco em crianças diagnosticadas com distrofia muscular de Duchenne (DMD). Desenho do estudo: Ensaio clínico randomizado controlado. Local: Ambulatório da Faculdade de Fisioterapia da Universidade de Benha, Egito. Participantes: Quarenta e oito crianças diagnosticadas com DMD, com idades compreendidas entre os 8 e os 12 anos. Intervenção: As crianças foram aleatoriamente alocadas a dois grupos iguais (n = 24 por grupo). O grupo experimental recebeu aplicação de BNM nos músculos extensores da cabeça e do tronco, em conjunto com o programa de fisioterapia tradicional (FT), durante 8 semanas. O grupo de controlo recebeu apenas o programa de FT pelo mesmo período. Principais medidas: As principais variáveis ​​​​incluíram a latência e a amplitude do reflexo H, avaliadas por eletromiografia nos músculos levantador da omoplata e iliocostal lombar. Adicionalmente, foi utilizada a Escala Multidimensional de Fadiga (MFS) do Inventário de Qualidade de Vida Pediátrica (PedsQL) tanto para as crianças como para os seus pais, tendo sido recolhidos dados no início do estudo e após a intervenção. Resultados: Os resultados mostraram diferenças significativas nos músculos levantador da omoplata e iliocostal lombar após um período de intervenção de oito semanas, com maiores alterações no grupo experimental em comparação com o grupo controlo. Além disso, a comparação dos escores do PedsQL e da MFS antes e depois da intervenção demonstrou melhorias significativas. Conclusões: A ligadura neuromuscular (BNM) pode melhorar o controlo da cabeça e do tronco em doentes com DMD.

The term fractal is used to describe an object displaying self-similarity at different scales. This self-similarity can be measured by either the power-law exponent or the ht-index, which is a recently proposed method for characterizing the fractal nature of geographic features. Although increasingly popular in geography, the ht-index is not sensitive to changes or evolutions of fractals, limiting its usefulness as an alternative \"fractal dimension\" to the power-law exponent. Two improvements to the ht-index were suggested in the literature, namely, the cumulative rate of growth (the CRG index) and the ratio of areas in a rank-size plot (the RA index). The CRG index is sensitive but not monotonic, however, with respect to the evolution of fractals. The RA index is both sensitive and monotonic but not interpretable in fractal terms. In this article, two novel metrics, referred to as unified metrics, are proposed by combining advantages of the ht-index and all of its improvements, being simultaneously easy to interpret, monotonic with respect to the evolution of fractals, and sensitive to changes in the evolution. The usefulness of unified metrics was demonstrated by both numerical experiments and case studies. Given that the idea behind the ht-index has led to a relaxed, emerging popular definition of fractals, the proposed unified metrics have great potential to be used as the standard fractal dimension along with such a definition.