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"Cancer Religious aspects."
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Facing cancer with Mary : reflections, prayers and spiritual practices
Catherine Stewart was not feeling well, but she never dreamed that she was suffering from stage 3 colon cancer. With her life suddenly turned upside down, she turned to Mary and the mysteries of the Rosary for solace and strength. Mary became her cherished companion through the devastating months of treatment. Now in recovery, Catherine shares her story so that we too can make Mary our travel companion through the devastating events of our own lives.
Book
Black Women and Breast Cancer
Christian theology at its core is a story about someone being in trouble.In response to this trouble, the triune God intervenes.God identifies with those in trouble, walking with them through the experience.Yet, the God of Christian theology goes a step further.God prevails over trouble.God is an overcomer.
eBook
Patient Spirituality as a Component of Supportive Care: Assessment and Intervention
National supportive care guidelines for patients with cancer include recognition of patients’ spirituality and spiritual needs. Experts differ on how best to address this dimension to our patients’ lives. Some suggest that patients’ medical team should take on spiritual care, and others suggest referral to chaplains or collaboration with outside clergy. In our view, the patient’s medical team ought to best acknowledge patient spirituality when so desired by the patient, but intervention in the case of serious spiritual crisis ought to be the responsibility of those with specific training in this realm. For some patients, “concordance” between the specific spiritual tradition of the patient and chaplain is necessary where for others, non-denominational, secular, or inter-faith chaplaincy services are welcome. The central role for physicians and nurses in this area, is listening, awareness, respect, and where necessary, referral.
Journal Article
Approaches to engaging faith communities in public health efforts regarding vaccination, genetics, and colorectal cancer: a systematic review
Background
Public health professionals regularly engage faith communities to improve public health. This systematic review characterizes approaches that public health professionals have used to engage faith communities and evaluates them using the Theory of Planned Behavior. It examines engagement regarding vaccination and genetic and genomic healthcare, which have generated significant controversy within religious groups and, for comparison, colorectal cancer screening, which has not.
Methods
This systematic review followed PRISMA reporting guidelines. We searched 8 online databases (e.g., Medline, Embase, Scopus). Publications in English that reported engaging a faith community on genetics, vaccination, or colorectal cancer screening were included. We screened 13,117 articles and extracted information from 121 articles reporting on 96 distinct projects.
Results
This review includes 121 articles reporting on 96 distinct projects. 67% of projects took place in the United States. Of these, 73% reported engaging racial or ethnic minorities; only 5% of projects reported engaging primarily White, Christian communities. Only 35% of projects reported addressing religious values that might inform attitudes and beliefs. The majority of publications (
n
= 74; 77.1%) reported primarily engaging faith communities for reasons unrelated to faith.
Conclusion
Because the Theory of Planned Behavior is widely used and our focus was on faith communities, we expected to see engagement with faith values and beliefs that might inform attitudes toward behaviors or social pressures community members perceive. Fewer than half of the projects reported addressing values or attitudes. There are missed opportunities to engage faith communities on religiously controversial public health initiatives in ways that are most likely to affect health behaviors. Evaluation of the outcomes of such engagement is needed.
Trial registration
The protocol is registered on Open Science Framework (OSF) at osf.io/r2c9n.
Journal Article
Exploring the relationship between spiritual well-being and death anxiety in patients with gynecological cancer: a cross-section study
Background
In recent years, spiritual well-being has gradually gained the attention of health care providers in China, especially those in oncology departments, who have recognized the importance of improving spiritual well-being in cancer patients. Since most of the current research on spiritual well-being has been carried out in areas with religious beliefs, this study was conducted in the context of no development of formal religion. The purpose of this study was to explore the relationship between death anxiety and spiritual well-being and the related factors of spiritual well-being among gynecological cancer patients.
Methods
This cross-section study was conducted among 586 gynecological cancer patients. The European Organization for Research and Treatment for Cancer Quality of Life Questionnaire-spiritual well-being32 (EORTC QLQ-SWB32) and Templer's Death Anxiety Scale (T-DAS) were used to measure spiritual well-being and death anxiety. The Multiple Linear Regression Model was used to determine the relationship between spiritual well-being and death anxiety.
Results
For all participants, the highest QLQ-SWB32 centesimal score was 75.13 on the Relationship with Other scale, and the lowest was 60.33 on the Relationship with Someone or Something Greater Scale. The mean Death Anxiety score was 5.31 (SD 3.18). We found that Relationship with Someone or Something Greater was the only scale not associated with death anxiety. Overall, patients with lower death anxiety have a higher level of spiritual well-being. Besides, a high Relationship with Other score was associated with living with a partner (B = 2.471,
P
< 0.001) and married (B = -6.475,
P
= 0.001). Patients with higher Global-SWB were retired (B = 0.387,
P
= 0.019).
Conclusions
Our study found that the spiritual well-being of patients with gynecological cancer in China was no worse than in other countries with religious beliefs and patients with lower death anxiety have a higher level of spiritual well-being. Clinical staff should pay attention to the spiritual health of cancer patients, and spiritual care should be regarded as an essential element in cancer care.
Journal Article
Role of religious social support in longitudinal relationships between religiosity and health-related outcomes in African Americans
This study tested a longitudinal model of religious social support as a potential mediator of the relationship between religious beliefs and behaviors, and multiple health-related outcomes (e.g., depressive symptoms, functioning, diet, alcohol use, cancer screening). A national probability sample of African Americans enrolled in the religion and health in African Americans study completed three waves of telephone interviews over a 5-year period (N = 766). Longitudinal structural equation models indicated that religious behaviors, but not beliefs, predicted the slowing of a modest overall decline in positive religious social support, while negative interactions with congregational members were stable. Positive religious support was associated with lower depressive symptoms and heavy drinking over time, while negative interaction predicted increases in depressive symptoms and decreases in emotional functioning. Positive religious support mediated the relationship between religious behaviors and depressive symptoms and heavy drinking. Findings have implications for mental health interventions in faith-based settings.
Journal Article
Relationship between spiritual well-being with anxiety and depression among cancer patients
Spiritual health is one of the basic concepts regarding how to deal with the problems caused by the disease. Anxiety and depression are common psychological consequences that affect the treatment process in cancer patients. Therefore, the present study has been conducted to explore relationship between spiritual well-being with anxiety and depression among cancer patients.
A total of 200 eligible cancer patients were included in this cross-sectional survey. Questionnaires of the Hospital Anxiety and Depression Scale (HADS) and Spiritual Well-Being Scale (SWB) were provided to patients.
The mean anxiety and depression scores were 9.98 ± 3.74 and 9.68 ± 3.32, respectively. Nearly half of the patients had anxiety and depression disorders. Age (β = -.300, P = .017) was a significant negative predictor for anxiety, and also education (β = -.885, P = .004) was a significant and negative predictor for depression. The mean score of patients' spiritual well-being was 76.61 ± 20.01, and its dimensions including existential well-being and religious well-being were 37.35 ± 9.78, and 39.27 ± 10.38, respectively. The majority of patients had a moderate level of spiritual well-being (81%). There was a statistically significant relationship between educational levels and spiritual well-being (P = 049), and religious well-being (P = 033). The spiritual well-being could significantly and negatively predict anxiety (β = -0.154, P < 0.001) and depression (β = -.134, P = < 0.001). There was a significant and inverse relationship between religious well-being with anxiety (rho = -.832, P < 0.001) and depression (rho = -.842, P < 0.001), and between existential well-being with anxiety (rho = -.830, P < 0.001) and depression (rho = -0.813, P < 0.001). There was a significant positive relationship between anxiety and depression (rho = 0.717, P < 0.001). The highest percentage of patients with depression disorder had more anxiety (75.6%).
Spirituality can serve as a protective factor for psychological morbidity. Spirituality wellbeing-based care programs are suggested as a good method to promote mental health in cancerous patients.
Journal Article
Cultural and religious influences on parental knowledge of HPV infection and female vaccination in Egypt: a national cross-sectional study
Background
Human Papilloma Virus (HPV) is one of the most prevalent sexually transmitted infections worldwide, significantly contributing to cervical and other cancers. In Egypt, where cultural and religious norms shape health perceptions, HPV prevention, especially vaccination, remains a critical public health issue. This study investigates parental knowledge and attitudes towards HPV infection and vaccination in Egypt, focusing on the influence of cultural and religious beliefs.
Methods
A national cross-sectional survey was conducted from January to April 2024 among 776 Egyptian parents. Participants were recruited using convenience and snowball sampling methods. A comprehensive questionnaire, translated and validated in Arabic, assessed knowledge about HPV and cervical cancer, beliefs about HPV vaccination, and vaccine acceptability. Data were analyzed using SPSS version 28, applying non-parametric tests to examine associations between demographic factors and study outcomes.
Results
While 38.5% of parents had heard of HPV, only 26.2% knew about the HPV vaccine. Higher education levels and income were significantly associated with better knowledge of HPV transmission and its link to cervical cancer. Cultural and religious factors played a pivotal role in shaping beliefs, with older and less educated parents showing lower levels of vaccine acceptance. Mothers were more willing than fathers to vaccinate themselves and their daughters, with willingness influenced by gender, age, and income.
Conclusion
Parental awareness of HPV and its vaccine remains low in Egypt, with significant cultural and religious influences on health beliefs and behaviors. Tailored public health interventions addressing these factors are needed to improve HPV vaccine uptake and reduce the burden of HPV-related diseases in Egypt.
Journal Article
Parents’ knowledge, beliefs, and acceptance of the HPV vaccination in relation to their socio-demographics and religious beliefs: A cross-sectional study in Thailand
Thailand has one of the world's highest prevalence of cervical cancer, mainly caused by the human papillomavirus (HPV). HPV infections can successfully be prevented by vaccination, which is available at a cost but not yet implemented in the national vaccination program. Parents play a critical role in deciding whether to vaccinate their child against HPV. Thus, the aim was to examine the association between parents' knowledge, beliefs, and acceptance of the HPV vaccination for their daughters, considering their socio-demographics and religious beliefs. A cross-sectional design was used among three schools in Thailand: Nakorn Phatom province (suburban) and Bangkok (urban). Parents of 9-12-year-old daughters completed the questionnaires, guided by the Health Belief Model. In total, 359 parents completed the questionnaires; of those, 301 were included in the final analyses. The ordinary least squares (OLS) regression analysis showed that background knowledge of HPV and the HPV vaccine was positively related to knowledge of HPV and cervical cancer. For beliefs, knowledge was positively associated with susceptibility (i.e., parents' perceived risk of an HPV infection/ related disease), severity, and benefit. However, knowledge was not significantly related to barriers. For acceptance, higher susceptibility and benefit were related to higher acceptance, and greater knowledge was associated with higher acceptance. Thus, we found associations between parents' knowledge, beliefs, and acceptance of the HPV vaccination for their daughters, considering their socio-demographics and religious beliefs. Parents, who reported religion as important, as opposed to those who did not, were more favorable toward the HPV vaccination. Four out of ten mothers had never undergone a cervical cancer screening, but most had accepted previous childhood vaccinations for their daughters. The overall acceptance of the vaccine was high, and we believe our results are promising for future implementation of the HPV vaccination in the national childhood vaccination program in Thailand.
Journal Article
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility
Here we use deep sequencing to identify sources of variation in mRNA splicing in the dorsolateral prefrontal cortex (DLPFC) of 450 subjects from two aging cohorts. Hundreds of aberrant pre-mRNA splicing events are reproducibly associated with Alzheimer’s disease. We also generate a catalog of splicing quantitative trait loci (sQTL) effects: splicing of 3,006 genes is influenced by genetic variation. We report that altered splicing is the mechanism for the effects of the
PICALM, CLU
and
PTK2B
susceptibility alleles. Furthermore, we performed a transcriptome-wide association study and identified 21 genes with significant associations with Alzheimer’s disease, many of which are found in known loci, whereas 8 are in novel loci. These results highlight the convergence of old and new genes associated with Alzheimer’s disease in autophagy–lysosomal-related pathways. Overall, this study of the transcriptome of the aging brain provides evidence that dysregulation of mRNA splicing is a feature of Alzheimer’s disease and is, in some cases, genetically driven.
Analysis of mRNA splicing in the dorsolateral prefrontal cortex from two cohorts established to study aging identifies variations in pre-mRNA splicing events that are associated with Alzheimer’s disease.
Journal Article