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The UK Initial Operational Response (IOR) to chemical incidents includes improvised decontamination procedures, which use readily available materials to rapidly reduce risk to potentially exposed persons. A controlled, cross-over human volunteer study was conducted to investigate the effectiveness of improvised dry and wet decontamination procedures on skin, both alone, and in sequence. A simulant contaminant, methyl salicylate (MeS) in vegetable oil with a fluorophore was applied to three locations (shoulder, leg, arm). Participants then received no decontamination (control) or attempted to remove the simulant using one of three improvised protocols (dry decontamination; wet decontamination; combined dry and wet decontamination). Simulant remaining on the skin following decontamination was quantified using both Gas Chromatography Tandem Mass Spectrometry (GC-MSMS) for analysis of MeS and UV imaging to detect fluorophores. Additionally, urine samples were collected for 24 hours following application for analysis of MeS. Significantly less simulant was recovered from skin following each improvised decontamination protocol, compared to the no decontamination control. Further, combined dry and wet decontamination resulted in lower recovery of simulant when compared to either dry or wet decontamination alone. Irrespective of decontamination protocol, significantly more simulant remained on the shoulders compared to either the arms or legs, suggesting that improvised decontamination procedures are less effective for difficult to reach areas of the body. There was no effect of decontamination on excreted MeS in urine over 24 hours. Overall, findings indicate that improvised decontamination is an effective means of rapidly removing contaminants from skin, and combinations of improvised approaches can increase effectiveness in the early stages of decontamination and in the absence of specialist resources at an incident scene. However, the variable control and consistency of improvised decontamination techniques means that further intervention is likely to be needed, particularly for less accessible areas of the body.

The market for ready‐to‐eat (RTE) crustaceans has been expanding in recent years. Conventional heating (CH) (boiling and steaming) has been used for decades for the processing of RTE crustaceans. However, some disadvantages, such as lack of uniformity of heating, low heat transfer efficiency, and generation of a large amount of wastewater, have been highlighted. To optimize the processing for safe and high‐quality RTE crustaceans, the identification of major hazards is necessary and the interventions of green, sustainable, and novel technologies attract increasing attention. In this review, important biological and chemical hazards in crustaceans are discussed. CH and promising novel thermal and nonthermal processing technologies are reviewed with their basic mechanisms and research advances in RTE crustacean processing. Then, challenges and future work are proposed. Biological hazards, including Listeria monocytogenes, norovirus, Salmonella, and Vibrio spp., are of great concern for raw crustaceans. L. monocytogenes is a persistent hazard that places a burden on crustacean processing environments. Most chemical hazards are caused by indigenous habitats, including heavy metals, biotoxins, pesticides, pharmaceuticals, and personal care products. Thermal technologies such as sous vide, moderate electric field, and microwave are promising in RTE crustacean processing. Individual effects on microbial hazards of nonthermal technologies like high‐pressure processing (HPP) and ultrasound (US) are limited. Synergistic effects of less intensity of nonthermal treatment with thermal processes such as HPP‐ and US‐assisted cooking showed great potential and advantages. However, more research is still needed to scale up their use in an industrial setting. Biological hazards, including Listeria monocytogenes, norovirus, Salmonella, and Vibrio spp., and chemical hazards, including heavy metals, biotoxins, pesticides, pharmaceuticals, and personal care products, are of great concern regarding crustaceans and their consumption. To improve the processing of ready‐to‐eat (RTE) crustacean products, novel thermal technologies such as sous vide, moderate electric field, and microwave can be promising substitutes for conventional boiling and steaming. Combining thermal and nonthermal technologies such as high‐pressure processing and ultrasound can also have great potential to improve RTE crustaceans' safety and quality.

Biomass gasification technology has been rapidly developed recently. But fire and poisoning accidents caused by gas leakage restrict the development and promotion of biomass gasification. Therefore, probabilistic safety assessment (PSA) is necessary for biomass gasification system. Subsequently, Bayesian network-bow-tie (BN-bow-tie) analysis was proposed by mapping bow-tie analysis into Bayesian network (BN). Causes of gas leakage and the accidents triggered by gas leakage can be obtained by bow-tie analysis, and BN was used to confirm the critical nodes of accidents by introducing corresponding three importance measures. Meanwhile, certain occurrence probability of failure was needed in PSA. In view of the insufficient failure data of biomass gasification, the occurrence probability of failure which cannot be obtained from standard reliability data sources was confirmed by fuzzy methods based on expert judgment. An improved approach considered expert weighting to aggregate fuzzy numbers included triangular and trapezoidal numbers was proposed, and the occurrence probability of failure was obtained. Finally, safety measures were indicated based on the obtained critical nodes. The theoretical occurrence probabilities in one year of gas leakage and the accidents caused by it were reduced to 1/10.3 of the original values by these safety measures.

Nitrate and nitrite content was determined on a total of 900 samples of vegetables and cured meat and the nitrite and nitrate exposure assessment was evaluated for central Italy population based on the food consumption data reported by the national dietary surveys. The highest average content of nitrate was detected in rocket salad (4415 mg/kg) and radish (3817 mg/kg) and for cured meat in “Bresaola” (188 mg/kg) and in Bacon (178 mg/kg). The nitrite content was negligible both in vegetables than in cured meat. The average consumption among population resulted 3.45 g/kg bw/die and 0.62 g/kg bw/die for vegetables and cured meat respectively. The obtained data confirm that nitrate ADI was higher than the limits of 3.7 mg/kg bw/die for infants and was the highest exposure level for people of all ages. Cured meat consumption did not contribute to nitrate ADI exceedance neither as a mean nor as 99th percentile of exposure.

The research purpose was to analyze data concerning chemical incidents in Poland collected in 1999-2009 in terms of health hazards. The data was obtained, using multimodal information technology (IT) system, from chemical incidents reports prepared by rescuers at the scene. The final analysis covered sudden events associated with uncontrolled release of hazardous chemical substances or mixtures, which may potentially lead to human exposure. Releases of unidentified substances where emergency services took action to protect human health or environment were also included. The number of analyzed chemical incidents in 1999-2009 was 2930 with more than 200 different substances released. The substances were classified into 13 groups of substances and mixtures posing analogous risks. Most common releases were connected with non-flammable corrosive liquids, including: hydrochloric acid (199 cases), sulfuric(VI) acid (131 cases), sodium and potassium hydroxides (69 cases), ammonia solution (52 cases) and butyric acid (32 cases). The next group were gases hazardous only due to physico-chemical properties, including: extremely flammable propane-butane (249 cases) and methane (79 cases). There was no statistically significant trend associated with the total number of incidents. Only with the number of incidents with flammable corrosive, toxic and/or harmful liquids, the regression analysis revealed a statistically significant downward trend. The number of victims reported was 1997, including 1092 children and 18 fatalities. The number of people injured, number of incidents and the high 9th place of Poland in terms of the number of Seveso establishments, and 4 times higher number of hazardous industrial establishments not covered by the Seveso Directive justify the need for systematic analysis of hazards and their proper identification. It is advisable enhance health risk assessment, both qualitative and quantitative, by slight modification of the data collection system so as to enable the determination of released chemical concentration and exposed populations. Int J Occup Med Environ Health 2017;30(1):95-110.

In view of the advantages of CFD technology in the simulation of small and medium-scale chemical hazard diffusion, one near-field prediction model of chemical hazard diffusion named CHDNFP is constructed based on CFD technology, and the accuracy and efficiency of the model are improved by improved differential evolution algorithm (DEA) and fireworks algorithm (FWA). Firstly, based on the component conservation equation, momentum conservation equation, and turbulence control equation, CHDNFP model is constructed, whose basic solution process is proposed from three aspects: non-uniform mesh refinement in diffusion space, model discretization, and iterative solution of control equation. Secondly, comprehensive considering the global search ability, local search ability, and convergence characteristics of integrated DEA and FWA, a hybrid optimization algorithm IDEFWA is designed, which is suitable for predictive model solving. Finally, the CHDNFP model and IDEFWA are verified by tracer experiments. The result shows that: IDEFWA can reduce the relative root mean square error between the predicted concentration field and the observed concentration field to about 25%, with the calculation accuracy of 10 –19 and the standard deviation accuracy of 10 –9 ; compared with ABCA and GA, IDEFWA can get more accurate solutions faster under the same algebraic and population conditions; the calculation accuracy of CHDNFP–IDEFWA and PISOFOAM is almost the same, where the relative difference is about 3%, and CHDNFP–IDEFWA has better calculation accuracy than PISOFOAM, which is improved by about 26.05%.

To reduce damage caused by chemical accidents, it is important to establish a prevention system for chemical accidents. The first step in the prevention of chemical accidents is to screen the high-risk chemical plants. Risk index, one of the screening methods, can indirectly estimate the risk at each chemical plant. For calculating the risk index, the probability of an accident needs to be estimated, which requires complex calculation and confidential data from plants that are difficult to obtain. Therefore, we developed a new index, the accident probability index, to estimate accident probability in chemical plants using readily accessible data. We conducted a literature survey on the existing risk indices and interviewed chemical experts and government chemical managers to select surrogate indicators related to chemical accidents, and four indicators were chosen: hazardous characteristics of chemicals, handling volume, records of accident frequency, and national accident frequency of chemicals. We calculated the accident probability index for 4520 chemical plants, and index value means was 5.324 (95% confidence interval (CI): 3.156, 7.493). An increase by 10 in the index value denoted a 1.06-fold (95% CI: 1.04, 1.08) increase in the odds ratio for actual accident occurrence. The accident frequency of the fourth quartile of the index value was 4.30 times (95% CI: 1.72, 10.75) higher than those of the first quartile.

Background In 1968, the Yusho incident resulted in accidental exposure to polychlorinated biphenyls (PCBs), polychlorinated dibenzofurans (PCDFs), and related compounds in Japan. This study updated the risk of mortality in Yusho patients. Methods We obtained updated cohort data for all Yusho patients for the period 1968–2017. We calculated standardized mortality ratios (SMRs) for all-cause and cause-specific mortality over a 50-year follow-up period compared with the general population in Japan. Results A total of 1664 Yusho patients with 63,566 person-years of follow up were included in the analysis. Among males, excess mortality was observed for all cancers (SMR: 1.22, 95% confidence interval [CI]: 1.02 to 1.45) and lung cancer (SMR: 1.59, 95% CI: 1.12 to 2.19). Among females, increased mortality was observed for liver cancer (SMR: 2.05, 95% CI: 1.02 to 3.67). No significant increase was seen in non-cancer-related mortality compared with the general population. Conclusions Carcinogenic risk in humans after exposure to PCBs and PCDFs remains higher among Yusho patients. Our findings suggest the importance of care engagement and optimum management to deal with the burden of Yusho disease.

Though concerns about the proliferation of synthetic chemicals – including pesticides – gave rise to the modem environmental movement in the early 1960s, synthetic chemical pollution has not been included in most analyses of global change. We examined the rate of change in the production and variety of pesticides, pharmaceuticals, and other synthetic chemicals over the past four decades. We compared these rates to those for well-recognized drivers of global change such as rising atmospheric CO₂ concentrations, nutrient pollution, habitat destruction, and biodiversity loss. Our analysis showed that increases in synthetic chemical production and diversification, particularly within the developing world, outpaced these other agents of global change. Despite these trends, mainstream ecological journals, ecological meetings, and ecological funding through the US National Science Foundation devote less than 2% of their journal pages, meeting talks, and science funding, respectively, to the study of synthetic chemicals.

Organic chemicals can contribute to local and regional losses of freshwater biodiversity and ecosystem services. However, their overall relevance regarding larger spatial scales remains unknown. Here, we present, to our knowledge, the first risk assessment of organic chemicals on the continental scale comprising 4,000 European monitoring sites. Organic chemicals were likely to exert acute lethal and chronic long-term effects on sensitive fish, invertebrate, or algae species in 14% and 42% of the sites, respectively. Of the 223 chemicals monitored, pesticides, tributyltin, polycyclic aromatic hydrocarbons, and brominated flame retardants were the major contributors to the chemical risk. Their presence was related to agricultural and urban areas in the upstream catchment. The risk of potential acute lethal and chronic long-term effects increased with the number of ecotoxicologically relevant chemicals analyzed at each site. As most monitoring programs considered in this study only included a subset of these chemicals, our assessment likely underestimates the actual risk. Increasing chemical risk was associated with deterioration in the quality status of fish and invertebrate communities. Our results clearly indicate that chemical pollution is a large-scale environmental problem and requires far-reaching, holistic mitigation measures to preserve and restore ecosystem health.