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"Communication Computer networks."
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‘Fit-for-purpose?’ – challenges and opportunities for applications of blockchain technology in the future of healthcare
by
Clauson, Kevin A.
,
Kuo, Tsung-Ting
,
Church, George
in
Beyond Big Data to new Biomedical and Health Data Science moving to next century precision health
,
Biomedical Technology - methods
,
Biomedical Technology - organization & administration
2019
Blockchain is a shared distributed digital ledger technology that can better facilitate data management, provenance and security, and has the potential to transform healthcare. Importantly, blockchain represents a data architecture, whose application goes far beyond Bitcoin – the cryptocurrency that relies on blockchain and has popularized the technology. In the health sector, blockchain is being aggressively explored by various stakeholders to optimize business processes, lower costs, improve patient outcomes, enhance compliance, and enable better use of healthcare-related data. However, critical in assessing whether blockchain can fulfill the hype of a technology characterized as ‘revolutionary’ and ‘disruptive’, is the need to ensure that blockchain design elements consider actual healthcare needs from the diverse perspectives of consumers, patients, providers, and regulators. In addition, answering the real needs of healthcare stakeholders, blockchain approaches must also be responsive to the unique challenges faced in healthcare compared to other sectors of the economy. In this sense, ensuring that a health blockchain is ‘fit-for-purpose’ is pivotal. This concept forms the basis for this article, where we share views from a multidisciplinary group of practitioners at the forefront of blockchain conceptualization, development, and deployment.
Journal Article
Supporting Regularized Logistic Regression Privately and Efficiently
2016
As one of the most popular statistical and machine learning models, logistic regression with regularization has found wide adoption in biomedicine, social sciences, information technology, and so on. These domains often involve data of human subjects that are contingent upon strict privacy regulations. Concerns over data privacy make it increasingly difficult to coordinate and conduct large-scale collaborative studies, which typically rely on cross-institution data sharing and joint analysis. Our work here focuses on safeguarding regularized logistic regression, a widely-used statistical model while at the same time has not been investigated from a data security and privacy perspective. We consider a common use scenario of multi-institution collaborative studies, such as in the form of research consortia or networks as widely seen in genetics, epidemiology, social sciences, etc. To make our privacy-enhancing solution practical, we demonstrate a non-conventional and computationally efficient method leveraging distributing computing and strong cryptography to provide comprehensive protection over individual-level and summary data. Extensive empirical evaluations on several studies validate the privacy guarantee, efficiency and scalability of our proposal. We also discuss the practical implications of our solution for large-scale studies and applications from various disciplines, including genetic and biomedical studies, smart grid, network analysis, etc.
Journal Article
A Secured Authentication Protocol for Wireless Sensor Networks Using Elliptic Curves Cryptography
by
Pin-Chuan Liu
,
Hsin-Wen Wei
,
Hsiu-Lien Yeh
in
Access control
,
authentication
,
Authentication protocols
2011
User authentication is a crucial service in wireless sensor networks (WSNs) that is becoming increasingly common in WSNs because wireless sensor nodes are typically deployed in an unattended environment, leaving them open to possible hostile network attack. Because wireless sensor nodes are limited in computing power, data storage and communication capabilities, any user authentication protocol must be designed to operate efficiently in a resource constrained environment. In this paper, we review several proposed WSN user authentication protocols, with a detailed review of the M.L Das protocol and a cryptanalysis of Das’ protocol that shows several security weaknesses. Furthermore, this paper proposes an ECC-based user authentication protocol that resolves these weaknesses. According to our analysis of security of the ECC-based protocol, it is suitable for applications with higher security requirements. Finally, we present a comparison of security, computation, and communication costs and performances for the proposed protocols. The ECC-based protocol is shown to be suitable for higher security WSNs.
Journal Article