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‘Fit-for-purpose?’ – challenges and opportunities for applications of blockchain technology in the future of healthcare
Blockchain is a shared distributed digital ledger technology that can better facilitate data management, provenance and security, and has the potential to transform healthcare. Importantly, blockchain represents a data architecture, whose application goes far beyond Bitcoin – the cryptocurrency that relies on blockchain and has popularized the technology. In the health sector, blockchain is being aggressively explored by various stakeholders to optimize business processes, lower costs, improve patient outcomes, enhance compliance, and enable better use of healthcare-related data. However, critical in assessing whether blockchain can fulfill the hype of a technology characterized as ‘revolutionary’ and ‘disruptive’, is the need to ensure that blockchain design elements consider actual healthcare needs from the diverse perspectives of consumers, patients, providers, and regulators. In addition, answering the real needs of healthcare stakeholders, blockchain approaches must also be responsive to the unique challenges faced in healthcare compared to other sectors of the economy. In this sense, ensuring that a health blockchain is ‘fit-for-purpose’ is pivotal. This concept forms the basis for this article, where we share views from a multidisciplinary group of practitioners at the forefront of blockchain conceptualization, development, and deployment.
Journal Article
Yammer : collaborate, connect, and share
Build a successful Yammer implementation, make your workplace social and collaborative, create a culture of sharing, form expert communities and generate innovative solutions. Besides, this book will help to enhance your collaboration your suppliers, partners, and clients. The author starts by giving an introduction to social collaborations and successful implementations of Yammer. Along the way, he explains the art of community management in Yammer using his hands-on experience of building communities. He then explains methods to keep a Yammer network engaged followed by a description of running a campaign on Yammer. The second part of Yammer begins with ways you can engage entire organizations, including executives, on Yammer along with methods to measure the success of a Yammer network. You'll see how to get to grips with integrating Yammer with an existing platform and how to collaborate with customers, suppliers, and partners using Yammer. Finally, you'll learn various innovative techniques of communication using Yammer and explore the author's vision of the next-generation Yammer platform. After reading this book you will understand how to make successful Yammer implementations, engage communities on Yammer, and accomplish business goals using Yammer. What You Will Learn: Master the art of community management ; Make your organization digital by implementing and integrating Yammer ; Break silos and create a collaborative workforce ; Keep Yammer groups live and full of participation ; Improve collaboration between suppliers, partners, and clients ; Measure the success of your Yammer network ; Increase employee engagement on Yammer.
Book
Towards 6G wireless communication networks: vision, enabling technologies, and new paradigm shifts
The fifth generation (5G) wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized, such as mass connectivity, ultra-reliability, and guaranteed low latency. However, 5G will not meet all requirements of the future in 2030 and beyond, and sixth generation (6G) wireless communication networks are expected to provide global coverage, enhanced spectral/energy/cost efficiency, better intelligence level and security, etc. To meet these requirements, 6G networks will rely on new enabling technologies, i.e., air interface and transmission technologies and novel network architecture, such as waveform design, multiple access, channel coding schemes, multi-antenna technologies, network slicing, cell-free architecture, and cloud/fog/edge computing. Our vision on 6G is that it will have four new paradigm shifts. First, to satisfy the requirement of global coverage, 6G will not be limited to terrestrial communication networks, which will need to be complemented with non-terrestrial networks such as satellite and unmanned aerial vehicle (UAV) communication networks, thus achieving a space-air-ground-sea integrated communication network. Second, all spectra will be fully explored to further increase data rates and connection density, including the sub-6 GHz, millimeter wave (mmWave), terahertz (THz), and optical frequency bands. Third, facing the big datasets generated by the use of extremely heterogeneous networks, diverse communication scenarios, large numbers of antennas, wide bandwidths, and new service requirements, 6G networks will enable a new range of smart applications with the aid of artificial intelligence (AI) and big data technologies. Fourth, network security will have to be strengthened when developing 6G networks. This article provides a comprehensive survey of recent advances and future trends in these four aspects. Clearly, 6G with additional technical requirements beyond those of 5G will enable faster and further communications to the extent that the boundary between physical and cyber worlds disappears.
Journal Article
Inference and analysis of cell-cell communication using CellChat
Understanding global communications among cells requires accurate representation of cell-cell signaling links and effective systems-level analyses of those links. We construct a database of interactions among ligands, receptors and their cofactors that accurately represent known heteromeric molecular complexes. We then develop CellChat, a tool that is able to quantitatively infer and analyze intercellular communication networks from single-cell RNA-sequencing (scRNA-seq) data. CellChat predicts major signaling inputs and outputs for cells and how those cells and signals coordinate for functions using network analysis and pattern recognition approaches. Through manifold learning and quantitative contrasts, CellChat classifies signaling pathways and delineates conserved and context-specific pathways across different datasets. Applying CellChat to mouse and human skin datasets shows its ability to extract complex signaling patterns. Our versatile and easy-to-use toolkit CellChat and a web-based Explorer (
http://www.cellchat.org/
) will help discover novel intercellular communications and build cell-cell communication atlases in diverse tissues.
Single-cell methods record molecule expressions of cells in a given tissue, but understanding interactions between cells remains challenging. Here the authors show by applying systems biology and machine learning approaches that they can infer and analyze cell-cell communication networks in an easily interpretable way.
Journal Article
An Overview of Emergency Communication Networks
In recent years, major natural disasters and public safety accidents have frequently occurred worldwide. In order to deal with various disasters and accidents using rapidly deployable, reliable, efficient, and stable emergency communication networks, all countries in the world are strengthening and improving emergency communication network construction and related technology research. Motivated by these situations, in this paper, we provide a state-of-the-art survey of the current situation and development of emergency communication networks. In this detailed investigation, our primary focus is the extensive discussion of emergency communication network technology, including satellite networks, ad hoc networks, cellular networks, and wireless private networks. Then, we explore and analyze the networks currently applied in emergency rescue, such as the 370M narrowband private network, broadband cluster network, and 5G constellation plan. We propose a broadband-narrowband integrated emergency communication network to provide an effective solution for visual dispatch of emergency rescue services. The main findings derived from the comprehensive survey on the emergency communication network are then summarized, and possible research challenges are noted. Lastly, we complete this survey by shedding new light on future directions for the emergency communication network. In the future, the emergency network will develop in the direction of intelligence, integration, popularization, and lower cost, and space-air-ground-sea integrated networks. This survey provides a reference basis for the construction of networks to mitigate major natural disasters and public safety accidents.
Journal Article