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"Coronary disease"
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Initial Invasive or Conservative Strategy for Stable Coronary Disease
Patients with stable coronary disease were randomly assigned to an initial invasive strategy with angiography and revascularization if appropriate or to medical therapy alone. At 3.2 years, there was no significant difference between the groups with respect to the estimated rate of ischemic events. The findings were sensitive to the definition of myocardial infarction.
Journal Article
Fractional Flow Reserve–Guided PCI for Stable Coronary Artery Disease
In this study, fractional flow reserve was used to identify patients with high-risk coronary stenoses, who received either PCI or medical therapy alone; patients with lower-risk lesions were entered in a registry. The PCI group had better outcomes than the medical-therapy group.
The benefit of percutaneous coronary intervention (PCI) as an initial treatment strategy in patients with stable coronary artery disease remains controversial.
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The potential result from revascularization depends on the extent and the degree of myocardial ischemia.
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A fractional flow reserve (FFR) value of 0.80 or less (i.e., a drop in maximal blood flow of 20% or more caused by stenosis), as measured with the use of a coronary pressure wire during catheterization, indicates the potential of a stenosis to induce myocardial ischemia.
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In such cases, robust clinical-outcome data favor FFR-guided revascularization, as compared with revascularization guided by . . .
Journal Article
Optical Coherence Tomography–Guided versus Angiography-Guided PCI
In a randomized trial, optical coherence tomography–guided PCI resulted in a larger minimum stent area than angiography-guided PCI, but there was no between-group difference in target-vessel failure at 2 years.
Journal Article
Five-Year Outcomes with PCI Guided by Fractional Flow Reserve
Patients with stable coronary artery disease were randomly assigned to fractional flow reserve–guided PCI or medical therapy. At 5 years, the composite of death, myocardial infarction, or urgent revascularization was significantly less frequent in the PCI group.
Journal Article
Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction
In patients with ST-segment elevation myocardial infarction, immediate multivessel PCI was noninferior to staged multivessel PCI with respect to the risk of death and adverse cardiovascular events at 1 year.
Journal Article
Intravascular Imaging–Guided or Angiography-Guided Complex PCI
In a randomized trial of imaging-guided or angiography-guided PCI for complex coronary lesion revascularization procedures, imaging-guided PCI led to a lower risk of target-vessel failure than angiography-guided PCI.
Journal Article