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An objective analysis of the human movement can help both clinical assessment and sports performance. Kinovea is a free 2D motion analysis software that can be used to measure kinematic parameters. This low-cost technology has been used in sports sciences, as well as in the clinical and research fields. One interesting tool is that it can measure an object (or person) passing in front of the camera, taking into account the perspective between the camera and the recorded object. Although it has been validated as a tool to assess time-related variables, few studies assessed its validity compared to a Gold Standard; furthermore, its reliability in different perspectives has not been previously assessed. The main objective of this study is to determine the validity of the Kinovea software compared to AutoCAD, and its intra and inter-rater reliability in obtaining coordinates data; a second objective is to compare their results at 4 different perspectives (90°, 75°, 60° and 45°) and to assess the inter and intra rater reliability at each perspective. For this purpose, a wire structure figure in the shape of a human lower limb was designed and measured in AutoCAD; it was then recorded during a pendular motion with a video-camera placed at distance of 5 m and analyzed with Kinovea in the 4 perspectives (90°, 75°, 60° and 45°). Each frame was examined by three observers who made two attempts. A multiple approach was applied involving the analysis of the systematic error, with a two-way ANOVA 2x4; the relative reliability with Intraclass Correlation Coefficient (ICC) and the Coefficient of Variance (CV) (95% confidence interval); and the absolute reliability with the Standard Error (SE). The results indicate that the Kinovea software is a valid and reliable tool that is able to measure accurately at distances up to 5 m from the object and at an angle range of 90°-45°. Nevertheless, for optimum results an angle of 90° is suggested.

Sample preparation of complex, natural mixtures such as lignin prior to mass spectrometry analysis, however minimal, is a critical step in ensuring accurate and interference-free results. Modern shotgun-MS techniques, where samples are directly injected into a high-resolution mass spectrometer (HRMS) with no prior separation, usually still require basic sample pretreatment such as filtration and appropriate solvents for full dissolution and compatibility with atmospheric pressure ionization interfaces. In this study, sample preparation protocols have been established for a unique sample set consisting of a wide variety of degraded lignin samples from numerous sources and treatment processes. The samples were analyzed via electrospray (ESI)-HRMS in negative and positive ionization modes. The resulting information-rich HRMS datasets were then transformed into the mass defect space with custom R scripts as well as the open-source Constellation software as an effective way to visualize changes between the samples due to the sample preparation and ionization conditions as well as a starting point for comprehensive characterization of these varied sample sets. Optimized conditions for the four investigated lignins are proposed for ESI-HRMS analysis for the first time, giving an excellent starting point for future studies seeking to better characterize and understand these complex mixtures. Graphical Abstract

Super-resolution optical fluctuation imaging (SOFI) allows one to perform sub-diffraction fluorescence microscopy of living cells. By analyzing the acquired image sequence with an advanced correlation method, i.e. a high-order cross-cumulant analysis, super-resolution in all three spatial dimensions can be achieved. Here we introduce a software tool for a simple qualitative comparison of SOFI images under simulated conditions considering parameters of the microscope setup and essential properties of the biological sample. This tool incorporates SOFI and STORM algorithms, displays and describes the SOFI image processing steps in a tutorial-like fashion. Fast testing of various parameters simplifies the parameter optimization prior to experimental work. The performance of the simulation tool is demonstrated by comparing simulated results with experimentally acquired data.

Despite the growing importance of human-centered design and ergonomics in various fields, a significant gap exists in applying these principles to robotic systems in airport environments. This paper focuses on a real-time baggage handling monitoring system by proposing a computational ergo-design approach. It presents the optimal system architecture for real-time baggage handling. The proposed architecture, called ARTEMIS (ARchitecture for real-TimE baggage handling and MonitorIng System), is designed for real-time baggage handling and monitoring. The circuit modeling is carried out using a directed graph. Five strategies are simulated to test their effectiveness and evaluate their performance within the system. A simulation that generates key indicators enables preliminary visualization and analysis of AGV behavior through predefined scenarios. These results are presented through an intuitive and ergonomic user interface, designed with a focus on user–computer interaction as a problem-solving process centered on the user’s experience. The results show that, if the goal is to balance energy efficiency with effective baggage handling, the Mixed Advance/Delay Strategy appears to be the best overall choice, as it optimizes both energy consumption and baggage handling while maintaining relatively low waiting times. However, if minimizing queue time and maximizing baggage collection are the highest priorities (with less emphasis on energy efficiency), the Turnstile Strategy remains a solid option. In addition, the simulations show that the operator plays a central role in minimizing delays and ensuring the smooth operation of the system. Both local and global system failures depend heavily on the operator’s response time, decision-making, and overall efficiency. Therefore, operator efficiency and a well-designed support system are critical to maintaining a smooth and effective baggage handling process.

Background Foot healthcare research is focusing increasingly on personalized orthotic and prosthetic devices to address patient-specific morphology and ailments. Customization requires advanced 3D image processing tools to assess foot and leg geometrical parameters and alterations. The aim of this study is to present a new software for the measurement of the foot shape from 3D scans of the foot plantar surface. Methods A Kinect-based scanning device was used to acquire the 3D foot shape of 44 healthy subjects. A software was developed in Matlab to measure the foot main morphological parameters from foot scans. Principal Component Analysis was used to orientate the foot scans with respect to the same reference system. Accuracy, via percentage errors and Bland-Altman plots, and correlation of the software-based foot parameters were assessed against manual measurements. A normalized Arch Volume Index (nAVI) was proposed and correlated to the traditional Arch Index. Test-retest Intraclass Correlation Coefficient was used to assess the inter-session repeatability of foot measurements. Results The average percentage error between software and manual measurements was 1.2 ± 0.8% for foot length, 9.1 ± 3.7% for foot width, 22.3 ± 13.5% for arch height and 23.1 ± 12.7% for arch depth. Very strong correlations were observed for foot length ( R  = 0.97) and foot width ( R  = 0.83), and strong correlations for arch height ( R  = 0.62) and arch depth ( R  = 0.74). nAVI was negatively correlated to the Arch Index ( R  = -0.54). A small difference was found between software and manual measurements of foot length (Δ = 0.92 mm), a software overestimation of foot width (Δ = 8.6 mm) and underestimation of arch height (Δ = -1.4%) and arch depth (Δ = -11%). Moderate to excellent repeatability was observed for all measurements (0.67–0.99). Conclusions The present software appears capable to estimate the foot main morphological parameters without the need for skin markers or for identification of anatomical landmarks. Moreover, measurements are not affected by the foot orientation on the scanning device. The good accuracy and repeatability of measurements make the software a potentially useful operator-independent tool for the assessment of foot morphological alterations and for orthotics customization. nAVI may be used for a more realistic classification of foot types when 3D foot images are available.

Ip3 Labs Hooks Up loT Devices Ip3 Labs of Little Rock began doing business in March as a mobile virtual network operator, meaning it connects \"internet of things\" (IoT) devices to the internet by accessing multiple cell service carriers at the same time through embedded SIM cards. The company offers its eSIM multi-carrier access and IoT management platform to organizations, other operators and service providers. The company also offers security via a virtual private network (VPN) connection.

The Coronavirus 2019 pandemic has strained nearly every aspect of pathology practice, including preanalytic, analytic, and postanalytic processes. Much of the challenges result from high demand for limited severe acute respiratory syndrome coronavirus 2 testing capacity, a resource required to facilitate patient flow throughout the hospital system and society at large. At our institution, this led to unprecedented increases in inquiries from providers to laboratory staff relating to the expected time to result for their patients. The demand was great enough to require redeployment of staff to handle the laboratory call volume. Although these data are available in our laboratory information system, the data do not interface to our electronic health record system. We developed systems using the R statistical programming language that abstract the necessary data regarding severe acute respiratory syndrome coronavirus 2 polymerase chain reaction testing from our lab system in real time, store it, and present it to clinicians for on demand querying. These data have been accessed over 2500 times by over 100 distinct users. Median length of each user session is approximately 4.9 minutes. Because our lab information system does not persistently store tracking information while our system does, we have been able to iteratively recalculate time to result values for each tracking stop as workflows have changed over time. Facility with informatics and programming concepts coupled with clinical understanding have allowed us to swiftly develop and iterate on applications which provide efficiency gains, allowing laboratory resources to focus on generating test results for our patients.

Automakers are set to reap the benefits of software-defined vehicles as they start to gain traction, enabling them to capitalize on recurring revenue streams and other key advantages. 2024 will see software-defined vehicles start to deliver on their potential, experts say. [...]Horn said that board-level executives need to adapt their mindsets and embrace new skill sets. To make a vehicle safe, operational, compliant with regulations and durable enough to be driven for decades, automakers still need to tap into their core in-house skills.

A design is presented for a hardware–software package based on a light-section device and intended for carrying out automated measurements of surface roughness. Package design solutions are presented and the metrological characteristics and features of the software are examined.

Many bidders in eBay use bidding strategies that involve late bids, incremental bids, or both. Based on field evidence, we discuss the manner in which late bids are caused both by sophisticated, strategic reasoning and by irrationality and inexperience; the interaction of late bidding with incremental bidding; and the relation between market design and artificial agent design.