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Direct Air Capture (DAC) is a promising technology to fight climate change by capturing carbon dioxide (CO2) from the air. For DAC to be a negative emissions technology, the captured CO2 must be removed permanently, but can also be used as a net-zero technology to produce sustainable chemicals, fuels or other materials. This review presents a comprehensive survey of recent advancements, challenges, and potential applications of DAC technology, with an emphasis on the recent rapid increase in the number of DAC developers, the majority of them being founded in the past 4 years. Through pilot projects and recent commercial deployments, several DAC companies have made significant advances and demonstrated their scalability. Cost and energy efficiency remain significant impediments to the wide deployment of DAC. Integration with emission-free energy sources and utilization of waste heat are being researched to boost the total energy efficiency of DAC systems. Further research of electrochemical technologies for regeneration or direct capture are needed, as well as the development of new, modified, or hybrid adsorbents for improved capture efficiencies. Moreover, favorable regulations and financial incentives are crucial for enhancing the viability of DAC projects and will need to substantially increase if Paris Agreement goals are to be achieved.