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With the end of civil war in 1991, Ethiopia’s government launched a New Education and Training Policy in 1994 which, by the early 2000s, had already produced remarkable results. The gross enrollment ratio rose from 20 to 62 percent in primary education between 1993-94 and 2001-02; and in secondary and higher education it climbed, respectively, from 8 to 12 percent and from 0.5 to 1.7 percent. Yet the government can hardly afford to rest on its laurels. Primary education is still not universal, and already there are concerns about plummeting educational quality and the growing pressures to expand post-primary education. Addressing these challenges will require more resources, both public and private. Yet money alone is insufficient. Focusing on primary and secondary education, Education in Ethiopia argues for wise tradeoffs in the use of resources—a result that will often require reforming the arrangements for service delivery. These changes, in turn, need to be fostered by giving lower levels of government more leeway to adapt central standards—such as those for teacher recruitment and school construction—to local conditions, including local resource constraints; and by strengthening accountability for results at all levels of administration in the education system.

Key Points Itch—also referred to as pruritus—is an unpleasant sensation that elicits an urge to scratch Neuropathic pruritus is caused by neuronal or glial damage CNS disorders rarely trigger pruritus, but pruritus is commonly associated with peripheral neuropathies and disorders of mixed or undetermined aetiology with neurological involvement Treatment for neuropathic pruritus is similar to that for neuropathic pain, but μ opioids can induce itch and are, therefore, contraindicated Pruritus is a very common condition, with almost one-third of the global population experiencing itch in a given week. Its origin is not always in the skin: damage to neurons or glia can induce neuropathic pruritus, which is often associated with neuropathic pain. Neuropathic pruritus is often difficult to treat and—if chronic—can severely impair quality of life. Here, Laurent Misery and colleagues review the role of the nervous system and neuropathic syndromes in pruritus, summarize the currently available therapeutic options, and propose therapeutic strategies for managing neuropathic pruritus. Pruritus, also known as itch, is a very common, unpleasant sensation that elicits an urge to scratch. Its origin is not always in the skin, and neuropathic itch that is caused by neuronal or glial damage is common, but poorly understood by both dermatologists and neurologists. Although pruritus has not been considered as serious a symptom as pain, it is difficult to treat and—if chronic—can severely impair quality of life. Neuropathic itch is often associated with other clinical symptoms, most commonly neuropathic pain, and hypersensitization to stimuli is present in both pruritus and pain of neuropathic origin. The shared aetiology can aid in finding suitable treatment for itch in some cases, but more detailed knowledge of the mechanisms of itch, along with standardized, well-controlled trials, is needed. Pruritus research is an emerging but currently very active field, and our understanding of this sensation is rapidly increasing. Here, we review new discoveries regarding the role of the nervous system and the contribution of different pathways in pruritus, discuss the different aetiologies of neuropathic itch, and outline currently available and potential strategies for managing neuropathic pruritus.

This paper aims to discover the general steady-state operation characteristics, as well as improving the dynamic performance, of the modular multilevel converter (MMC)-based unified power flow controller (UPFC). To achieve this, first, we established a detailed power flow model for MMC-based UPFC containing each critical part and made qualitative and graphical analyses combining 2-dimensional operation planes and 3-dimensional spatial curve surfaces comprehensively to derive general power flow principles and offer necessary references for regulating UPFC. Furthermore, to achieve better performance, we designed a feedforward control strategy for the shunt and series converters of UPFC, both comprising two feedforward control blocks with the introduction of necessary compensating branches, and analyzed the performance in complex and time domain, respectively. The proposed power flow principles and control strategies were validated by a (power systems computer aided design) PSCAD model of 220 kV double-end system; the results reveal the MMC-based UPFC can realize the power flow principles and improve the control speed, stability, and precision of the power flow regulations under various conditions.

Porcine hemagglutinating encephalomyelitis virus (PHEV) is a member of the genus betacoronavirus within the family coronaviridae, which invades the central nervous system (CNS) via peripheral nervous system and causes encephalomyelitis or vomiting and wasting disease (VWD) in sucking piglets. Up to now, although few complete nucleotide sequences of PHEV have been reported, they are not annotated. This study aimed to illuminate genome characterization, phylogenesis and pathogenicity of the PHEV/2008 strain. The full length of the PHEV/2008 strain genome was 30,684 bp, with a G + C content of 37.27%. The genome included at a minimum of 11 predicted open reading frames (ORFs) flanked by 5′ and 3′ untranslated regions (UTR) of 211 and 289 nucleotides. The replicase polyproteins pp1a and pp1ab, which had 4382 and 7094 amino acid residues, respectively, were predicted to be cleaved into 16 subunits by two viral proteinases. Phylogenetic analysis based on the complete genome sequence revealed that PHEV/2008 strain was genetically different from other known PHEV types, which represented a novel genotype (GI-1). In addition, we found that PHEV/2008 was neurotropic and highly pathogenic to 4-week-old BALB/c mice. Taken together, this is the first detailed annotated, complete genomic sequence of a new genotype PHEV strain in China.

In this paper, knocking combustion in dual-fuel diesel engine is modeled and investigated using the CFD code coupled with detailed chemical kinetics. The ethanol/gasoline blend E85 is used as the primary fuel in a dual-fuel combustion concept based on a light-duty diesel engine equipped with a common-rail injection system. The E85 blend is injected and well mixed with intake air in the intake manifold and is ignited by the direct injection diesel fuel. A 46-species, 187-reaction Multicomponent mechanism is adopted to model the auto-ignition process of the E85/air/diesel mixture ahead of the flame front. Based on the model validation, knocking combustion under boost and full load operating condition for 0 %, 20 %, 50 %, as well as 70 % E85 substitute energy is simulated. The effects of E85 substitute rate and two stage injection strategies on knock intensity, power output, as well as location of the auto-ignition initiation is clearly reproduced by the model. The calculation result shows that, for a high E85 rate of 50 % and 70 % with single injection strategies, the most serious knock and the origin of auto-ignition always occurs far away from where the flame of diesel spray is first generated, at the center of combustion chamber, due to higher pressure wave, relatively richer E85 mixture and longer distances of flame propagation. The two stage injection strategies with a small amount of diesel pilot injection ahead of the main injection primarily influence the ignition behavior of the directly injected fuel, leads to a lower pressure rise rate and a reduced propagation distance, both of which contribute to the attenuation of knock intensity for a higher E85 rate.

Finding out the effective ways of teaching and assessing communication skills remain a challenging part of medication education. This study aims at exploring the usefulness and effectiveness of having additional feedback using qualitative analysis in assessment of communication skills in undergraduate medical training. We also determined the possibilities of using qualitative analysis in developing tailored strategies for improvement in communication skills training. This study was carried out on medical students (n=87) undergoing their final year clinical performance examination on communication skills using standardized patient by video-recording and transcribing their performances. Video-recordings of 26 students were randomly selected for qualitative analysis, and additional feedback was provided. We assessed the level of acceptance of communication skills scores between the study and nonstudy group and within the study group, before and after receiving feedback based on qualitative analysis. There was a statistically significant increase in the level of acceptance of feedback after delivering additional feedback using qualitative analysis, where the percentage of agreement with feedback increased from 15.4 to 80.8% (p<0.001). Incorporating feedback based on qualitative analysis for communication skills assessment gives essential information for medical students to learn and self-reflect, which could potentially lead to improved communication skills. As evident from our study, feedback becomes more meaningful and effective with additional feedback using qualitative analysis.

Based on the characters of interior space in small area houses, this paper gives summarization of the typical design strategy of indoor dwelling unit type design. It makes study on different households requirements and the main design problem in small apartment.

The management of inflammatory bowel disease represents a key component of clinical practice for members of the British Society of Gastroenterology (BSG). There has been considerable progress in management strategies affecting all aspects of clinical care since the publication of previous BSG guidelines in 2004, necessitating the present revision.Key components of the present document worthy of attention as having been subject to re-assessment, and revision, and having direct impact on practice include:The data generated by the nationwide audits of inflammatory bowel disease (IBD) management in the UK in 2006, and 2008.The publication of ‘Quality Care: service standards for the healthcare of people with IBD’ in 2009.The introduction of the Montreal classification for Crohn's disease and ulcerative colitis.The revision of recommendations for the use of immunosuppressive therapy.The detailed analysis, guidelines and recommendations for the safe and appropriate use of biological therapies in Crohn's disease and ulcerative colitis.The reassessment of the role of surgery in disease management, with emphasis on the importance of multi-disciplinary decision-making in complex cases.The availablity of new data on the role of reconstructive surgery in ulcerative colitis.The cross-referencing to revised guidelines for colonoscopic surveillance, for the management of metabolic bone disease, and for the care of children with inflammatory bowel disease.Use of the BSG discussion forum available on the BSG website to enable ongoing feedback on the published document http://www.bsg.org.uk/forum (accessed Oct 2010).The present document is intended primarily for the use of clinicians in the United Kingdom, and serves to replace the previous BSG guidelines in IBD, while complementing recent consensus statements published by the European Crohn's and Colitis Organisation (ECCO) https://www.ecco-ibd.eu/index.php (accessed Oct 2010).

This chapter contains sections titled: Abstract Introduction The Magnitude of the Problem Follow‐up Treatments for Suicide Attempters Recommended Standards of Care and Aftercare of Suicide Attempters Adherence to Recommended Treatment Standards The Norwegian Chain of Care Model Conclusions and Recommendations for Policy and Clinical Practice References

This chapter contains sections titled: Talented Thinking Inventive Engineers – Thinking in Time and Scale for System Context and All Requirements Why Use Time and Scale? Time and Scale Can Be Used in at Least Four Ways Unidentified Manufacturing Problem – Scrap Rate Rises Dramatically Use 9‐Boxes to Understand History/Context of a Problem Conclusion: TRIZ Aim is to Increase Ideality and Subdue Complexity Case Study: Applying Time and Scale to Nuclear Decommissioning Research Sites Restoration Limited– an Estimating Workshop