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After the peace
\"How many parents does it take to make a baby? In the case of Rosalind Melrose Smithson it took four: one birth mother; one legal father; one interfering neighbour and one turkey baster filled with the defrosted essence of an anonymous donor. Or not so anonymous as it turned out. For donor no. 116349, '6ft 1in, blue eyes, blond hair, BA (Oxon), action man, aristocrat' is the ninth Earl of Dilberne, who gave his seed back in 1979 as a stripling of twenty-two, and has now conceived a daughter - unknowingly - at the riper age of forty-two. As they say, the truth will out. And what will our Rozzie do when she finds out about dear old dad? All we know is that as a true Millennial, she will not take it lying down... Sharp, insightful and full of Weldon's trademark wit, this is a tale of family life, genetics and class that reflects the way we live our lives now\"-- Publisher's description.
Book
Sex cells
Unimaginable until the twentieth century, the clinical practice of transferring eggs and sperm from body to body is now the basis of a bustling market. In Sex Cells, Rene Almeling provides an inside look at how egg agencies and sperm banks do business. Although both men and women are usually drawn to donation for financial reasons, Almeling finds that clinics encourage sperm donors to think of the payments as remuneration for an easy \"job.\" Women receive more money but are urged to regard egg donation in feminine terms, as the ultimate \"gift\" from one woman to another. Sex Cells shows how the gendered framing of paid donation, as either a job or a gift, not only influences the structure of the market, but also profoundly affects the individuals whose genetic material is being purchased.
eBook
Regulating reproductive donation
This title brings together different disciplinary perspectives and new empirical insights to explore the regulation of assisted reproduction around the world.
Book
Nine pints : a journey through the money, medicine, and mysteries of blood
\"Blood carries life, yet the sight of it makes people faint. It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don't even know their own blood type ... Rose George ... takes us from ancient practices of bloodletting to the breakthough of the 'liquid biopsy,' which promises to diagnose cancer and other diseases with a simple blood test\"--Publisher marketing.
Book
The INTERVAL trial to determine whether intervals between blood donations can be safely and acceptably decreased to optimise blood supply: study protocol for a randomised controlled trial
Background
Ageing populations may demand more blood transfusions, but the blood supply could be limited by difficulties in attracting and retaining a decreasing pool of younger donors. One approach to increase blood supply is to collect blood more frequently from existing donors. If more donations could be safely collected in this manner at marginal cost, then it would be of considerable benefit to blood services. National Health Service (NHS) Blood and Transplant in England currently allows men to donate up to every 12 weeks and women to donate up to every 16 weeks. In contrast, some other European countries allow donations as frequently as every 8 weeks for men and every 10 weeks for women. The primary aim of the INTERVAL trial is to determine whether donation intervals can be safely and acceptably decreased to optimise blood supply whilst maintaining the health of donors.
Methods/Design
INTERVAL is a randomised trial of whole blood donors enrolled from all 25 static centres of NHS Blood and Transplant. Recruitment of about 50,000 male and female donors started in June 2012 and was completed in June 2014. Men have been randomly assigned to standard 12-week versus 10-week versus 8-week inter-donation intervals, while women have been assigned to standard 16-week versus 14-week versus 12-week inter-donation intervals. Sex-specific comparisons will be made by intention-to-treat analysis of outcomes assessed after two years of intervention. The primary outcome is the number of blood donations made. A key secondary outcome is donor quality of life, assessed using the Short Form Health Survey. Additional secondary endpoints include the number of ‘deferrals’ due to low haemoglobin (and other factors), iron status, cognitive function, physical activity, and donor attitudes. A comprehensive health economic analysis will be undertaken.
Discussion
The INTERVAL trial should yield novel information about the effect of inter-donation intervals on blood supply, acceptability, and donors’ physical and mental well-being. The study will generate scientific evidence to help formulate blood collection policies in England and elsewhere.
Trial registration
Current Controlled Trials
ISRCTN24760606
, 25 January 2012.
Journal Article
806 : a novel
KT, sixteen, learns that her father was Donor 806, discovers two half-brothers, and travels with them from Missouri to California to meet their biological father, redefining their notions of \"family\" along the way.
Book
