Explore the vast range of titles available.

[This corrects the article DOI: 10.1155/2024/7645490.].

This report presents the fluocinolone-loaded intraocular lens (IOL) with scleral suspension (FLISS) technique as a surgical approach for managing macular edema (ME) in patients with compromised lens–iris diaphragm and dislocated IOL. A 74-year-old woman with a subluxated bag–IOL complex and chronic ME underwent pars plana vitrectomy. After IOL removal, Gore-Tex CV-8 sutures were used to secure a 0.19-mg fluocinolone acetonide (FAc) intravitreal implant (Iluvien) to the haptic of a Micro-pure IOL and subsequently fix the lens to the sclera. Three months later, visual acuity had improved from 20/160 to 20/50, and there was no ME. The FAc implant remained stable and well positioned outside the visual axis. The FLISS technique, herein described for the first time, offers a promising alternative for addressing chronic ME in eyes requiring secondary IOL implantation, with the benefits of no additional scleral manipulation (compared to standard IOL scleral fixation) and low risk of implant migration.

Background and Purpose: Subgroups of very low and high age were excluded or underrepresented in past mechanical thrombectomy (MT) landmark trials. Although younger age is linked to better outcome it is also an established risk factor for malignant infarction with poor outcome. Yet, the effect of age on lesion pathophysiology on the context of MT has been poorly investigated. This study aims to investigate the impact of age on ischemic lesion water homeostasis, which is the pathophysiological hallmark of brain infarction. Methods: A prospectively collected data set of patients receiving MT for LVO within the anterior circulation was retrospectively analyzed. Lesion-NWU was quantified in multimodal admission CT and follow-up CT, and [DELTA]-NWU was calculated as difference. Consequently NWU edema formation was analyzed and compared in different age groups (<74 vs. >74). Moreover, the effect of edema formation was analyzed with regard to the final recanalization status. Results: Baseline characteristics showed no significant differences in NIHSS, NWU and time from onset to imaging between age groups on admission. At follow-up imaging, [DELTA]-NWU was significantly higher in younger patients. In multivariate linear regression analysis there was an independent significant association (p = 0.0116) for final delta NWU showing a development of higher edema formation in younger patients (95CI: -0.184 -2.54). Further independent significance (p < 0.001) was observed for status of vessel recanalization with less edema formation after successful recanalization (TICI [greater than or equal to]2b). Conclusion: Younger age was significantly associated with higher edema formation independent of treatment, which might have an important impact on clinical outcome. Younger patients with LVO might especially benefit form adjuvant treatment with anti-edematous drugs such as glyburide.