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\"Both recalling his life story and recounting many of the major advances in twentieth-century science, a renowned physicist shares his autobiography through letters. While recognizing that quantum mechanics \"demands serious attention,\" Albert Einstein in 1926 admonished fellow physicist Max Born that the theory \"does not bring us closer to the secrets of the Old One.\" Aware that \"there are deep mysteries that Nature intends to keep for herself,\" Freeman Dyson, the 94-year-old theoretical physicist, has nonetheless chronicled the stories of those who were engaged in solving some of the most challenging quandaries of twentieth-century physics. Written between 1940 and the early 1980s, these letters to relatives form an historic account of modern science and its greatest players, including J. Robert Oppenheimer, Richard Feynman, Stephen Hawking, and Hans Bethe. Whether reflecting on the horrors of World War II, the moral dilemmas of nuclear development, the challenges of the space program, or the considerable demands of raising six children, Dyson offers a firsthand account of one of the greatest periods of scientific discovery of our modern age\"-- Provided by publisher.

In this study, we present a new approach with semi-analytical and numerical findings for solving equations of motion of small orbiter m, which is moving under the combined gravitational attraction of three primaries, M1, M2, and M3, in case of the bi-elliptic restricted problem of four bodies (BiER4BP), where three such primaries, M1, M2, and M3, are moving on elliptic orbits with hierarchical configuration M3 << M2 << M1 within one plane as follows: third primary body M3 is moving on elliptical orbit around second M2, and second primary M2 is moving on elliptical orbit around first M1. Our aim for constructing the aforementioned quasi-planar motion of planetoid m is obtaining its coordinates supporting its orbit in a regime of close motion to the plane of orbiting the main bodies M1, M2, and M3. Meanwhile, the system of equations of motion was successfully numerically explored with respect to the existence and stable positioning of approximate solution for a Dyson sphere. As a result, the concept of the Dyson sphere for possible orbiting variety of solar energy absorbers was transformed to the elongated Dyson space net with respect to their trajectories for the successful process of absorbing the energy from the Sun; this can be recognized as symmetry reduction. We obtain the following: (1) the solution for coordinates x, y is described by the simplified system of two nonlinear ordinary differential equations of second order, depending on true anomaly f; (2) the expression for coordinate z is given by an equation of Riccati-type where small orbiter that quasi-oscillates close to the fixed plane x,y,0.

\"My friendship with Freeman Dyson goes back over a half century. My first contact with him goes back to the late 1950s, when I was at the Institute for Advanced Study, and then evolved when I was a consultant at General Atomics in La Jolla, California. Freeman was then trying to design a space ship -- the Orion -- which would be propelled by atomic bombs. When I left the Institute, Freeman and I continued our correspondence and I saved his letters. They are written in an almost calligraphically elegant handwriting. It is hard to see how you could make a mistake in a mathematical computation if you wrote that clearly. The letters show his human side and his enormous range of knowledge. There are then two essays involving the physicist Fritz Houtermans who was an extraordinarily colorful character. There is a brief essay on Einstein's collaboration with a fraud. There is even an essay on the Titius-Bode law and the new exo-planets. Because of my enduring interest in nuclear weapons, the reader will find essays devoted to that. There is also a bit of fiction at the end\"-- Provided by publisher.

Brilliant polymath who reshaped quantum physics Freeman Dyson, a towering figure in physics and mathematics, died on 28 February at the age of 96. During his long and vibrant life, Dyson explored both concrete and visionary technologies, ranging from safe, small nuclear reactors to proposals to genetically modify trees so they could grow on comets. He documented his adventures in beautifully written books and a marvelous collection of Web of Science video interviews. Dyson's most impactful contribution to physics was his fundamental work on quantum electrodynamics (QED), the theory of how matter interacts with the electromagnetic field. His synthesis of ideas completed the physical foundation for chemistry, materials science, laser physics, and electrical engineering.

In quasi-Hermitian quantum mechanics (QHQM) of unitary systems, an optimal, calculation-friendly form of Hamiltonian is generally non-Hermitian, H≠H†. This makes its physical interpretation ambiguous. Without altering H, this ambiguity can be resolved either via a transformation of H into its isospectral Hermitian form via a so-called Dyson map Ω:H→h, or via a (formally equivalent) specification of a nontrivial physical inner-product metric Θ in Hilbert space. Here, we focus on the former strategy. Our present construction of the Hermitian isospectral twins h of H is exhaustive. As a byproduct, it not only restores the conventional correspondence principle between quantum and classical physics, but it also provides a framework for a systematic classification of all of the admissible probabilistic interpretations of quantum systems using a preselected H in QHQM framework.

Nuclear physicist, polymath, disarmament pioneer and government adviser. Nuclear physicist, polymath, disarmament pioneer and government adviser.

Structural chemistry provides the foundation for progress in organic and inorganic chemistry with far-reaching consequences in medicine and in materials science and technology. New tools and concepts appear shaping together the progress in structural chemistry.

Series Editors' NoteThe beauty of science is that all the important things are unpredictable.Freeman DysonIn the typescript which follows, Moodie and Krakow tackle the topical issue of precision medicine and statistical methods for estimating adaptive treatment strategies. This may be the most difficult typescript in our series so far for non-statisticians to understand. It even has equations! But please bear with the authors and give it a chance. One needs not to understand the equations to get the thrust of the strategy.Precision medicine as we discuss elsewhere, is misnamed. In statistics and mathematics precision refers to getting the same answer again and again. It does not mean getting the correct answer, the term for which is accuracy, not precision. However, precision is the current buzz word so there’s no point trying to get this straight. When we think about precision we need to consider two elements, reproducibility and replicability. Reproducibility means you give me your data and computer code and I come to the same conclusion you did. Replicability is another matter. I try to replicate your experiment and hopefully reach the same conclusion. In medicine, replicability is obviously more important than reproducibility but things which cannot be reproduced are unlikely to be replicated.As the authors discuss, one can think about precision medicine as one does a family vacation. A best vacation depends on several co-variates: where you live, your prior travel experiences, advice from family and friends, online reviews, Wikitravel, cost, your travel budget, if you have kids and many other co-variates. Consequently, there is unlikely to be a best vacation for everyone. Yours might be a week at the Ritz Carlton Cancun with dinner at Careyes and ours, a week at the Pfister Hotel in Milwaukee with dinner at Mader’s German Restaurant (bring simvastatin). Similarly, it is unlikely there is a best therapy of acute myeloid leukemia, a best donor, a best conditioning regimen, a best posttransplant immune suppressive regimen etc. and certainly no best combination of these co-variates for your patient.The question Moodie and Krakow tackle is how we can determine the best therapy or combination of therapies for someone receiving a haematopoietic cell transplant. Although the default answer is typically: randomized clinical trials are the gold standard, these inform us of the outcome of a cohort of subjects, not individuals. In many instances, although a new therapy may be shown to be better than an old one in a controlled randomized trial the benefit is not uniformly distributed. Some subjects in the experimental cohort may do worse with the new therapy compared with controls, others better. The question is who are the winners and losers? We cannot do a controlled randomized trial of one person. Moodie and Krakow discuss statistical tools to help us sort this out.Again, please do not be put off by the equations; forgetaboutit. The overriding message is not so complex, and important. We are always standing by on twitter @BMTStats to help. But don’t confuse us with Match.com. And, by the way, Freeman Dyson was a professor at the Institute for Advanced Studies at Princeton but never got his PhD.Robert Peter Gale, Imperial College London, and Mei-Jie Zhang, Medical College of Wisconsin, Center for International Blood and Marrow Research (CIBMTR).

Ann Leckie’s space opera Ancillary Justice represents the cybernetic logics of modern life as a galactic empire of always-connected starships, artificial intelligences, and soldiers. In doing so, Leckie’s novel transforms cybernetics from its current state—a seemingly immaterial, dominant set of logics described by Seb Franklin, building on Deleuze and Foucault, as a “control episteme”—into corporeal form. This materialization occurs through that lyrical mimesis that Seo-Young Chu describes as characteristic of science fiction, a genre that is a “mimetic discourse whose objects of representation are nonimaginary yet cognitively estranging.” This act of representation exposes the vulnerabilities of cybernetic systems as inevitably, ultimately embodied, and reminds us of cybernetic logics’ origins in military technologies. I argue that Leckie’s novel opens a path for how these systems might be resisted: by individuals exercising ethical action and performing acts of care in the face of world-ending crises.