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Financial modeling : an introductory guide to Excel and VBA applications in finance
This volume provides a comprehensive introduction to modern financial modelling using Excel, VBA, standards of financial modelling and model review. It offers guidance on essential modelling concepts around the four core financial activities in the modern financial industry today: financial management; corporate finance; portfolio management and financial derivatives.
Book
Mathematics and computation in imaging science and information processing
The explosion of data arising from rapid advances in communication, sensing and computational power has concentrated research effort on more advanced techniques for the representation, processing, analysis and interpretation of data sets. In view of these exciting developments, the program “Mathematics and Computation in Imaging Science and Information Processing” was held at the Institute for Mathematical Sciences, National University of Singapore, from July to December 2003 and in August 2004 to promote and facilitate multidisciplinary research in the area. As part of the program, a series of tutorial lectures were conducted by international experts on a wide variety of topics in mathematical image, signal and information processing.
eBook
Quantitative assessments of distributed systems : methodologies and techniques
Distributed systems employed in critical infrastructures must fulfill dependability, timeliness, and performance specifications. Since these systems most often operate in an unpredictable environment, their design and maintenance require quantitative evaluation of deterministic and probabilistic timed models. This need gave birth to an abundant literature devoted to formal modeling languages combined with analytical and simulative solution techniques
The aim of the book is to provide an overview of techniques and methodologies dealing with such specific issues in the context of distributed systems and covering aspects such as performance evaluation, reliability/availability, energy efficiency, scalability, and sustainability. Specifically, techniques for checking and verifying if and how a distributed system satisfies the requirements, as well as how to properly evaluate non-functional aspects, or how to optimize the overall behavior of the system, are all discussed in the book. The scope has been selected to provide a thorough coverage on issues, models. and techniques relating to validation, evaluation and optimization of distributed systems. The key objective of this book is to help to bridge the gaps between modeling theory and the practice in distributed systems through specific examples.
eBook
Ecological niches and geographic distributions
This book provides a first synthetic view of an emerging area of ecology and biogeography, linking individual- and population-level processes to geographic distributions and biodiversity patterns. Problems in evolutionary ecology, macroecology, and biogeography are illuminated by this integrative view. The book focuses on correlative approaches known as ecological niche modeling, species distribution modeling, or habitat suitability modeling, which use associations between known occurrences of species and environmental variables to identify environmental conditions under which populations can be maintained. The spatial distribution of environments suitable for the species can then be estimated: a potential distribution for the species. This approach has broad applicability to ecology, evolution, biogeography, and conservation biology, as well as to understanding the geographic potential of invasive species and infectious diseases, and the biological implications of climate change.
The authors lay out conceptual foundations and general principles for understanding and interpreting species distributions with respect to geography and environment. Focus is on development of niche models. While serving as a guide for students and researchers, the book also provides a theoretical framework to support future progress in the field.
eBook
Fringe pattern analysis for optical metrology : theory, algorithms, and applications
Fringe Pattern Analysis for Optical Metrology: Theory, Algorithms, and Applications
The main objective of this book is to present the basic theoretical principles and practical applications for the classical interferometric techniques and the most advanced methods in the field of modern fringe pattern analysis applied to optical metrology. A major novelty of this work is the presentation of a unified theoretical framework based on the Fourier description of phase shifting interferometry using the Frequency Transfer Function (FTF) along with the theory of Stochastic Process for the straightforward analysis and synthesis of phase shifting algorithms with desired properties such as spectral response, detuning and signal-to-noise robustness, harmonic rejection, etc.
eBook
Variability in the analysis of a single neuroimaging dataset by many teams
Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses
1
. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset
2
–
5
. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.
The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
Journal Article
Performance Modeling and Design of Computer Systems
Tackling the questions that systems designers care about, this book brings queueing theory decisively back to computer science. The book is written with computer scientists and engineers in mind and is full of examples from computer systems, as well as manufacturing and operations research. Fun and readable, the book is highly approachable, even for undergraduates, while still being thoroughly rigorous and also covering a much wider span of topics than many queueing books. Readers benefit from a lively mix of motivation and intuition, with illustrations, examples and more than 300 exercises – all while acquiring the skills needed to model, analyze and design large-scale systems with good performance and low cost. The exercises are an important feature, teaching research-level counterintuitive lessons in the design of computer systems. The goal is to train readers not only to customize existing analyses but also to invent their own.
eBook
Computational paralinguistics : emotion, affect and personality in speech and language processing
This book presents the methods, tools and techniques that are currently being used to recognise (automatically) the affect, emotion, personality and everything else beyond linguistics ('paralinguistics') expressed by or embedded in human speech and language.
It is the first book to provide such a systematic survey of paralinguistics in speech and language processing. The technology described has evolved mainly from automatic speech and speaker recognition and processing, but also takes into account recent developments within speech signal processing, machine intelligence and data mining.
Moreover, the book offers a hands-on approach by integrating actual data sets, software, and open-source utilities which will make the book invaluable as a teaching tool and similarly useful for those professionals already in the field.
Key features:
* Provides an integrated presentation of basic research (in phonetics/linguistics and humanities) with state-of-the-art engineering approaches for speech signal processing and machine intelligence.
* Explains the history and state of the art of all of the sub-fields which contribute to the topic of computational paralinguistics.
* C overs the signal processing and machine learning aspects of the actual computational modelling of emotion and personality and explains the detection process from corpus collection to feature extraction and from model testing to system integration.
* Details aspects of real-world system integration including distribution, weakly supervised learning and confidence measures.
* Outlines machine learning approaches including static, dynamic and context?sensitive algorithms for classification and regression.
* Includes a tutorial on freely available toolkits, such as the open-source 'openEAR' toolkit for emotion and affect recognition co-developed by one of the authors, and a listing of standard databases and feature sets used in the field to allow for immediate experimentation enabling the reader to build an emotion detection model on an existing corpus.
eBook
A machine learning model to predict the risk of 30-day readmissions in patients with heart failure: a retrospective analysis of electronic medical records data
Background
Heart failure is one of the leading causes of hospitalization in the United States. Advances in big data solutions allow for storage, management, and mining of large volumes of structured and semi-structured data, such as complex healthcare data. Applying these advances to complex healthcare data has led to the development of risk prediction models to help identify patients who would benefit most from disease management programs in an effort to reduce readmissions and healthcare cost, but the results of these efforts have been varied. The primary aim of this study was to develop a 30-day readmission risk prediction model for heart failure patients discharged from a hospital admission.
Methods
We used longitudinal electronic medical record data of heart failure patients admitted within a large healthcare system. Feature vectors included structured demographic, utilization, and clinical data, as well as selected extracts of un-structured data from clinician-authored notes. The risk prediction model was developed using deep unified networks (DUNs), a new mesh-like network structure of deep learning designed to avoid over-fitting. The model was validated with 10-fold cross-validation and results compared to models based on logistic regression, gradient boosting, and maxout networks. Overall model performance was assessed using concordance statistic. We also selected a discrimination threshold based on maximum projected cost saving to the Partners Healthcare system.
Results
Data from 11,510 patients with 27,334 admissions and 6369 30-day readmissions were used to train the model. After data processing, the final model included 3512 variables. The DUNs model had the best performance after 10-fold cross-validation. AUCs for prediction models were 0.664 ± 0.015, 0.650 ± 0.011, 0.695 ± 0.016 and 0.705 ± 0.015 for logistic regression, gradient boosting, maxout networks, and DUNs respectively. The DUNs model had an accuracy of 76.4% at the classification threshold that corresponded with maximum cost saving to the hospital.
Conclusions
Deep learning techniques performed better than other traditional techniques in developing this EMR-based prediction model for 30-day readmissions in heart failure patients. Such models can be used to identify heart failure patients with impending hospitalization, enabling care teams to target interventions at their most high-risk patients and improving overall clinical outcomes.
Journal Article
Prediction of higher-selectivity catalysts by computer-driven workflow and machine learning
Asymmetric catalysis is widely used in chemical research and manufacturing to access just one of two possible mirror-image products. Nonetheless, the process of tuning catalyst structure to optimize selectivity is still largely empirical. Zahrt et al. present a framework for more efficient, predictive optimization. As a proof of principle, they focused on a known coupling reaction of imines and thiols catalyzed by chiral phosphoric acid compounds. By modeling multiple conformations of more than 800 prospective catalysts, and then training machine-learning algorithms on a subset of experimental results, they achieved highly accurate predictions of enantioselectivities. Science , this issue p. eaau5631 A model encompassing multiple conformations of chiral phosphoric acid catalysts accurately predicts enantioselectivities. Catalyst design in asymmetric reaction development has traditionally been driven by empiricism, wherein experimentalists attempt to qualitatively recognize structural patterns to improve selectivity. Machine learning algorithms and chemoinformatics can potentially accelerate this process by recognizing otherwise inscrutable patterns in large datasets. Herein we report a computationally guided workflow for chiral catalyst selection using chemoinformatics at every stage of development. Robust molecular descriptors that are agnostic to the catalyst scaffold allow for selection of a universal training set on the basis of steric and electronic properties. This set can be used to train machine learning methods to make highly accurate predictive models over a broad range of selectivity space. Using support vector machines and deep feed-forward neural networks, we demonstrate accurate predictive modeling in the chiral phosphoric acid–catalyzed thiol addition to N -acylimines.
Journal Article