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The Origins of AIDS
It is now thirty years since the discovery of AIDS but its origins continue to puzzle doctors and scientists. Inspired by his own experiences working as an infectious diseases physician in Africa, Jacques Pepin looks back to the early twentieth-century events in Africa that triggered the emergence of HIV/AIDS and traces its subsequent development into the most dramatic and destructive epidemic of modern times. He shows how the disease was first transmitted from chimpanzees to man and then how urbanization, prostitution, and large-scale colonial medical campaigns intended to eradicate tropical diseases combined to disastrous effect to fuel the spread of the virus from its origins in Léopoldville to the rest of Africa, the Caribbean and ultimately worldwide. This is an essential new perspective on HIV/AIDS and on the lessons that must be learnt if we are to avoid provoking another pandemic in the future.
eBook
Patient zero : a curious history of the world's worst diseases
\"From the masters of storytelling-meets-science and co-authors of Quackery, Patient Zero tells the long and fascinating history of disease outbreaks-how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors' lively and accessible style, chapters include page-turning medical stories about a particular disease or virus-smallpox, Bubonic plague, polio, HIV-that combine \"Patient Zero\" narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more. Learn the tragic stories of Patient Zeros throughout history, such as Mabalo Lokela, who contracted Ebola while on vacation in 1976, and the Lewis Baby on London's Broad Street, the first to catch cholera in an 1854 outbreak that led to a major medical breakthrough. Interspersed are origin stories of a different sort-how a rye fungus in 1951 turned a small village in France into a phantasmagoric scene reminiscent of Burning Man. Plus the uneasy history of human autopsy, how the HIV virus has been with us for at least a century, and more\"-- Provided by publisher.
BOOK
SARS : a case study in emerging infections
The sudden appearance and rapid spread of Severe Acute Respiratory Syndrome (SARS) in 2003 alerted the world to the fact that emerging infections are a global problem. Living in affluent societies with well-developed healthcare systems does not necessarily protect people from the dangers posed by life-threatening infections. The SARS epidemic tested global preparedness for dealing with a new infectious agent and raised important questions: How did we do, and what did we learn? This book uses the SARS outbreak as a case study to enumerate the generic issues that must be considered when planning the control of emerging infections. Emerging infections are more than just a current biological fashion: the bitter ongoing experience of AIDS and the looming threat of pandemic influenza teach us that the control of infectious disease is a problem that has not been solved. Scientists from a broad range of disciplines — biologists, veterinarians, physicians, and policy makers — all need to prepare. But prepare for what? The book provides an overview of the tasks that must be addressed by a community that wishes to confront emerging infections. While focusing on SARS, the book addresses a whole range of considerations and issues, from the use of new mathematical models to account for the spread of infection across global airline networks, to a discussion of the ethics of quarantining individuals in order to protect communities.
eBook
Emerging infectious diseases
Emerging Infectious Diseases offers an introduction to emerging and reemerging infectious disease, focusing on significant illnesses found in various regions of the world. Many of these diseases strike tropical regions or developing countries with particular virulence, others are found in temperate or developed areas, and still other microbes and infections are more indiscriminate. This volume includes information on the underlying mechanisms of microbial emergence, the technology used to detect them, and the strategies available to contain them. The author describes the diseases and their causative agents that are major factors in the health of populations the world over. The book contains up-to-date selections from infectious disease journals as well as information from the Centers for Disease Control and Prevention, the World Health Organization, MedLine Plus, and the American Society for Microbiology. Perfect for students or those new to the field, the book contains Summary Overviews (thumbnail sketches of the basic information about the microbe and the associated disease under examination), Review Questions (testing students' knowledge of the material), and Topics for Further Discussion (encouraging a wider conversation on the implications of the disease and challenging students to think creatively to develop new solutions). This important volume provides broad coverage of a variety of emerging infectious diseases, of which most are directly important to health practitioners in the United States.
eBook
One Health, emerging infectious diseases and wildlife: two decades of progress?
Infectious diseases affect people, domestic animals and wildlife alike, with many pathogens being able to infect multiple species. Fifty years ago, following the wide-scale manufacture and use of antibiotics and vaccines, it seemed that the battle against infections was being won for the human population. Since then, however, and in addition to increasing antimicrobial resistance among bacterial pathogens, there has been an increase in the emergence of, mostly viral, zoonotic diseases from wildlife, sometimes causing fatal outbreaks of epidemic proportions. Concurrently, infectious disease has been identified as an increasing threat to wildlife conservation. A synthesis published in 2000 showed common anthropogenic drivers of disease threats to biodiversity and human health, including encroachment and destruction of wildlife habitat and the human-assisted spread of pathogens. Almost two decades later, the situation has not changed and, despite improved knowledge of the underlying causes, little has been done at the policy level to address these threats. For the sake of public health and wellbeing, human-kind needs to work better to conserve nature and preserve the ecosystem services, including disease regulation, that biodiversity provides while also understanding and mitigating activities which lead to disease emergence. We consider that holistic, One Health approaches to the management and mitigation of the risks of emerging infectious diseases have the greatest chance of success.
This article is part of the themed issue ‘One Health for a changing world: zoonoses, ecosystems and human well-being’.
Journal Article
Animals, diseases, and human health : shaping our lives now and in the future
\"This book explains how animals shape our lives and our health, providing evidence that a \"One Health\" approach is the only logical methodology for advancing human health in the future\"--Provided by publisher.
Book
Infectious Disease Movement in a Borderless World
Modern transportation allows people, animals, and plants-and the pathogens they carry-to travel more easily than ever before. The ease and speed of travel, tourism, and international trade connect once-remote areas with one another, eliminating many of the geographic and cultural barriers that once limited the spread of disease. Because of our global interconnectedness through transportation, tourism and trade, infectious diseases emerge more frequently; spread greater distances; pass more easily between humans and animals; and evolve into new and more virulent strains.
The IOM's Forum on Microbial Threats hosted the workshop \"Globalization, Movement of Pathogens (and Their Hosts) and the Revised International Health Regulations\" December 16-17, 2008 in order to explore issues related to infectious disease spread in a \"borderless\" world. Participants discussed the global emergence, establishment, and surveillance of infectious diseases; the complex relationship between travel, trade, tourism, and the spread of infectious diseases; national and international policies for mitigating disease movement locally and globally; and obstacles and opportunities for detecting and containing these potentially wide-reaching and devastating diseases. This document summarizes the workshop.
eBook