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In an effort to reach accident-free milestones or drastically reduce/eliminate road fatalities rates and traffic congestion and to create disruptive, transformational mobility systems and services, different parties (e.g., automakers, universities, governments, and road traffic regulators) have collaborated to research, develop, and test connected vehicle (CV) technologies. CVs create new data-rich environments and are considered key enablers for many applications and services that will make our roads safer, less congested, and more eco-friendly. A deeper understanding of the CV technologies will pave the way to avoid setbacks and will help in developing more innovative applications and breakthroughs. In the CV paradigm, vehicles become smarter by communicating with nearby vehicles, connected infrastructure, and the surroundings. This connectivity will be substantial to support different features and systems, such as adaptive routing, real-time navigation, and slow and near real-time infrastructure. Further examples include environmental sensing, advanced driver-assistance systems, automated driving systems, mobility on demand, and mobility as a service. This article provides a comprehensive review on CV technologies including fundamental challenges, state-of-the-art enabling technologies, innovative applications, and potential opportunities that can benefit automakers, customers, and businesses. The current standardization efforts of the forefront enabling technologies, such as Wi-Fi 6 and 5G-cellular technologies are also reviewed. Different challenges in terms of cooperative computation, privacy/security, and over-the-air updates are discussed. Safety and non-safety applications are described and possible future opportunities that CV technology brings to our life are also highlighted.

Stopes suffer from unreliable wireless communication due to their harsh environment. There is a lack of confidence within industry regarding the effectiveness of existing solutions in providing reliable high-bandwidth performance in hard rock stopes. This work proposes that Wi-Fi6 is a good candidate for reliable high-bandwidth communications in underground hard rock stopes. Experiments in a tunnel and mine stope were conducted to evaluate the performance of Wi-Fi6 in terms of latency, jitter, and throughput. Different criteria, such as multi-hop systems, varying multipath, mesh routing protocols, and frequencies at different bandwidths, were used to evaluate performance. The results show that Wi-Fi6 performance is greater in stopes compared to tunnels. Signal quality evaluations were conducted using the Asus RT-AX53U running OpenWrt, and an additional experiment was conducted on the nrf7002dk running Zephyr OS to evaluate the power consumption of Wi-Fi6 against the industry standard for low-powered wireless communications, IEEE 802.15.4. Wi-Fi6 was found to be more power-efficient than IEEE 802.15.4 for Mbps communications. These experiments highlight the signal robustness of Wi-Fi6 in stope environments and also highlights its low-powered nature. This work also highlights the performance of the two most widely used open-source mesh routing protocols for Wi-Fi.

Influenza virus infection is a significant global health threat. Because of the lack of cross-protective universal vaccines, short time window during which antivirals are effective and drug resistance, new therapeutic anti-influenza strategies are required. Broadly, cross-protective antibodies that target conserved sites in the hemagglutinin (HA) stem region have been proposed as therapeutic agents. FI6 is the first proven such monoclonal antibody to bind to H1-H16 and is protective in mice and ferrets. Multiple studies have shown that Fc-dependent mechanisms are essential for FI6 efficacy. Here, we show that therapeutic administration of FI6 either intravenously or by aerosol to pigs did not reduce viral load in nasal swabs or broncho-alveolar lavage, but aerosol delivery of FI6 reduced gross pathology significantly. We demonstrate that pig Fc receptors do not bind human IgG1 and that FI6 did not mediate antibody-dependent cytotoxicity (ADCC) with pig PBMC, confirming that ADCC is an important mechanism of protection by anti-stem antibodies . Enhanced respiratory disease, which has been associated with pigs with cross-reactive non-neutralizing anti-HA antibodies, did not occur after FI6 administration. Our results also show that neutralizing antibody responses are not a robust correlate of protection for the control of influenza infection and pathology in a natural host model.

Mobile-learning (M-Learning) is no longer a futuristic concept in E-learning. The disruptions induced by the mandatory social distancing norms amidst the COVID-19 pandemic has brought it to the centre stage as it facilitates seamless delivery of education to mobile-users on the go. The ever increasing penetration of low-cost smartphones and remarkable advancement in wireless communication technologies has made M-learning ubiquitous and affordable. This paper highlights the roles that mass-adoption of mobile phone devices have played in sustaining K-12 schools. We review the impact that latest developments in communication technology and the deployment of LTE-WiFi coexistence, 5G, and Wi-Fi6 networks will have on M-learning applications. Further, we highlight the challenges that need to be addressed so that the higher penetration of mobile phones and deployment of wireless network technologies can be optimally harnessed for an improved M-learning experience.