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Electromagnetic induction plays a crucial impact on the firing activity of biological neurons, since it exists along with the mutual effect between membrane potential and ions transport. Flux-controlled memristor is an available candidate in characterizing the electromagnetic induction effect. Different from the previously reported literature, a non-ideal flux-controlled memristor with cosine mem-conductance function is employed to determine the periodic magnetization and leakage flux processes in neurons. Thereafter, a three-dimensional (3D) memristive Wilson (m-Wilson) neuron model is constructed under the consideration of this kind of electromagnetic induction. Numerical simulations are performed by multiple numerical tools, which demonstrate that the 3D m-Wilson neuron model can generate abundant firing activities. Interestingly, coexisting firing activities, antimonotonicity, and firing frequency regulation are discovered under special parameter settings. Furthermore, a PCB-based analog circuit is designed and hardware measurements are executed to verify the numerical simulations. These explorations in numerical and hardware surveys might provide insights to regulate the firing activities by appropriate electromagnetic induction.

On this episode, The Washington Post's Libby Casey, Rhonda Colvin and James Hohmann break down President Trump's apparent strategy of pushing norms and testing the U.S. court system to see how far he can push his policies. The crew looks at how Trump has approached firing federal workers and immigration – and how the court system has handled legal challenges on both policy fronts. Plus, has the Supreme Court largely given his policies a pass, or is it reigning him in?

I exploit the adoption of state-level labor protection laws as an exogenous increase in employee firing costs to examine how the costs associated with discharging workers affect capital structure decisions. I find that firms reduce debt ratios following the adoption of these laws, with this result stronger for firms that experience larger increases in firing costs. I also document that, following the adoption of these laws, a firm's degree of operating leverage rises, earnings variability increases, and employment becomes more rigid. Overall, these results are consistent with higher firing costs crowding out financial leverage via increasing financial distress costs.

According to legendary business guru Peter Drucker, the purpose of any business is to create and keep a customer. According to The Wall Street Journal, \"The devils are its worst customers. Before casting off customers, you need to understand the criteria for analyzing which relationships need to be terminated. 2 Based on our research, we suggest focusing on needs, behavior, and customer value. [...]they can easily provide an explanation of exactly why they want to terminate a relationship.

Cortical fast-spiking (FS) neurons generate high-frequency action potentials (APs) without apparent frequency accommodation, thus providing fast and precise inhibition. However, the maximal firing frequency that they can reach, particularly in primate neocortex, remains unclear. Here, by recording in human, monkey, and mouse neocortical slices, we revealed that FS neurons in human association cortices (mostly temporal) could generate APs at a maximal mean frequency (F ) of 338 Hz and a maximal instantaneous frequency (F ) of 453 Hz, and they increase with age. The maximal firing frequency of FS neurons in the association cortices (frontal and temporal) of monkey was even higher (F 450 Hz, F 611 Hz), whereas in the association cortex (entorhinal) of mouse it was much lower (F 215 Hz, F 342 Hz). Moreover, FS neurons in mouse primary visual cortex (V1) could fire at higher frequencies (F 415 Hz, F 582 Hz) than those in association cortex. We further validated our data by examining spikes of putative FS neurons in behaving monkey and mouse. Together, our results demonstrate that the maximal firing frequency of FS neurons varies between species and cortical areas.

The close replication of synaptic functions is an important objective for achieving a highly realistic memristor-based cognitive computation. The emulation of neurobiological learning rules may allow the development of neuromorphic systems that continuously learn without supervision. In this work, the Bienenstock-Cooper-Munro learning rule, as a typical case of spike-rate-dependent plasticity, is mimicked using a generalized triplet-spike-timing-dependent plasticity scheme in a WO 3−x memristive synapse. It demonstrates both presynaptic and postsynaptic activities and remedies the absence of the enhanced depression effect in the depression region, allowing a better description of the biological counterpart. The threshold sliding effect of Bienenstock-Cooper-Munro rule is realized using a history-dependent property of the second-order memristor. Rate-based orientation selectivity is demonstrated in a simulated feedforward memristive network with this generalized Bienenstock-Cooper-Munro framework. These findings provide a feasible approach for mimicking Bienenstock-Cooper-Munro learning rules in memristors, and support the applications of spatiotemporal coding and learning using memristive networks. Designing reliable and energy efficient neuromorphic computing systems for spatiotemporal coding remains a challenge. Here, the authors demonstrate a type of spike-rate-dependent plasticity based on a triplet learning scheme in a WO 3−x -based second-order memristor network for spatiotemporal patterns.

Various hypotheses of information representation in brain, referred to as neural codes, have been proposed to explain the information transmission between neurons. Neural coding plays an essential role in enabling the brain-inspired spiking neural networks (SNNs) to perform different tasks. To search for the best coding scheme, we performed an extensive comparative study on the impact and performance of four important neural coding schemes, namely, rate coding, time-to-first spike (TTFS) coding, phase coding, and burst coding. The comparative study was carried out using a biological 2-layer SNN trained with an unsupervised spike-timing-dependent plasticity (STDP) algorithm. Various aspects of network performance were considered, including classification accuracy, processing latency, synaptic operations (SOPs), hardware implementation, network compression efficacy, input and synaptic noise resilience, and synaptic fault tolerance. The classification tasks on Modified National Institute of Standards and Technology (MNIST) and Fashion-MNIST datasets were applied in our study. For hardware implementation, area and power consumption were estimated for these coding schemes, and the network compression efficacy was analyzed using pruning and quantization techniques. Different types of input noise and noise variations in the datasets were considered and applied. Furthermore, the robustness of each coding scheme to the non-ideality-induced synaptic noise and fault in analog neuromorphic systems was studied and compared. Our results show that TTFS coding is the best choice in achieving the highest computational performance with very low hardware implementation overhead. TTFS coding requires 4x/7.5x lower processing latency and 3.5x/6.5x fewer SOPs than rate coding during the training/inference process. Phase coding is the most resilient scheme to input noise. Burst coding offers the highest network compression efficacy and the best overall robustness to hardware non-idealities for both training and inference processes. The study presented in this paper reveals the design space created by the choice of each coding scheme, allowing designers to frame each scheme in terms of its strength and weakness given a designs’ constraints and considerations in neuromorphic systems.

Neuroscience is experiencing a revolution in which simultaneous recording of thousands of neurons is revealing population dynamics that are not apparent from single-neuron responses. This structure is typically extracted from data averaged across many trials, but deeper understanding requires studying phenomena detected in single trials, which is challenging due to incomplete sampling of the neural population, trial-to-trial variability, and fluctuations in action potential timing. We introduce latent factor analysis via dynamical systems, a deep learning method to infer latent dynamics from single-trial neural spiking data. When applied to a variety of macaque and human motor cortical datasets, latent factor analysis via dynamical systems accurately predicts observed behavioral variables, extracts precise firing rate estimates of neural dynamics on single trials, infers perturbations to those dynamics that correlate with behavioral choices, and combines data from non-overlapping recording sessions spanning months to improve inference of underlying dynamics.

Despite the success of Deep Neural Networks—a type of Artificial Neural Network (ANN)—in problem domains such as image recognition and speech processing, the energy and processing demands during both training and deployment are growing at an unsustainable rate in the push for greater accuracy. There is a temptation to look for radical new approaches to these applications, and one such approach is the notion that replacing the abstract neuron used in most deep networks with a more biologically-plausible spiking neuron might lead to savings in both energy and resource cost. The most common spiking networks use rate-coded neurons for which a simple translation from a pre-trained ANN to an equivalent spike-based network (SNN) is readily achievable. But does the spike-based network offer an improvement of energy efficiency over the original deep network? In this work, we consider the digital implementations of the core steps in an ANN and the equivalent steps in a rate-coded spiking neural network. We establish a simple method of assessing the relative advantages of rate-based spike encoding over a conventional ANN model. Assuming identical underlying silicon technology we show that most rate-coded spiking network implementations will not be more energy or resource efficient than the original ANN, concluding that more imaginative uses of spikes are required to displace conventional ANNs as the dominant computing framework for neural computation.

In the last decade, several models with network adaptive mechanisms (link deletion-creation, dynamic synapses, dynamic gains) have been proposed as examples of self-organized criticality (SOC) to explain neuronal avalanches. However, all these systems present stochastic oscillations hovering around the critical region that are incompatible with standard SOC. Here we make a linear stability analysis of the mean field fixed points of two self-organized quasi-critical systems: a fully connected network of discrete time stochastic spiking neurons with firing rate adaptation produced by dynamic neuronal gains and an excitable cellular automata with depressing synapses. We find that the fixed point corresponds to a stable focus that loses stability at criticality. We argue that when this focus is close to become indifferent, demographic noise can elicit stochastic oscillations that frequently fall into the absorbing state. This mechanism interrupts the oscillations, producing both power law avalanches and dragon king events, which appear as bands of synchronized firings in raster plots. Our approach differs from standard SOC models in that it predicts the coexistence of these different types of neuronal activity.