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result(s) for
"Fox, Paul"
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Spatiotemporal coordination of cell division and growth during organ morphogenesis
by
Fox, Samantha
,
Bangham, J. Andrew
,
Southam, Paul
in
Arabidopsis - genetics
,
Arabidopsis - growth & development
,
Arabidopsis Proteins - genetics
2018
A developing plant organ exhibits complex spatiotemporal patterns of growth, cell division, cell size, cell shape, and organ shape. Explaining these patterns presents a challenge because of their dynamics and cross-correlations, which can make it difficult to disentangle causes from effects. To address these problems, we used live imaging to determine the spatiotemporal patterns of leaf growth and division in different genetic and tissue contexts. In the simplifying background of the speechless (spch) mutant, which lacks stomatal lineages, the epidermal cell layer exhibits defined patterns of division, cell size, cell shape, and growth along the proximodistal and mediolateral axes. The patterns and correlations are distinctive from those observed in the connected subepidermal layer and also different from the epidermal layer of wild type. Through computational modelling we show that the results can be accounted for by a dual control model in which spatiotemporal control operates on both growth and cell division, with cross-connections between them. The interactions between resulting growth and division patterns lead to a dynamic distributions of cell sizes and shapes within a deforming leaf. By modulating parameters of the model, we illustrate how phenotypes with correlated changes in cell size, cell number, and organ size may be generated. The model thus provides an integrated view of growth and division that can act as a framework for further experimental study.
Journal Article
LEGAL HIGHS FRIED MY SON'S BRAIN
by
Gordon, Ali
in
Fox, Paul
2016
\"[Aaron] had his demons,\" [Paul Fox] told Sunday Life ahead of Aaron's Month's Mind mass this morning at 11am at St Vincent de Paul in north Belfast. BRAVE \"He was happy for it to be displayed in school, even when I asked him was he okay for people in school to know what was going on in his head. He looked at me and said: 'Daddy, that's the idea'. He had thought it all through and I thought that was very brave.\" \"Young boys don't want to talk to people, it's almost like it's a sign of weakness, but if the right facilities were in place then more people would get over that and get the help they need before it's too late.
Newspaper Article
Israeli Women's Leadership Today: A Panel Discussion
2008
A panel discussion about Jewish women's leadership in terms of their life's accomplishments featuring Brenda Bacon, Paul Sheryl-Fox, Hannah Kehat, Einat Ramon, and Vered Madar with the moderation by Leah Shakdiel, is presented. Bacon tells that people have different personalities and different ways of functioning--in every society there are some women who takes command while others don't. Nothing has been achieved by feminism without a collective struggle--it begins with women uniting, coming out of their private domains into the public sphere, politicizing these issues and moving them forward.
Journal Article