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The lives of fungi : a natural history of our planet's decomposers
\"A fascinating and richly illustrated exploration of the natural history of fungi. We know fungi are important, for us as well as the environment. But how they live, and what they can do, remains mysterious and surprising. Filled with stunning photographs, The Lives of Fungi presents an inside look into their hidden and extraordinary world. The wonders of fungi are myriad: a mushroom poking up through leaf litter literally overnight, or the sensational hit of umami from truffle shavings. Alexander Fleming cured infections with mold and spiritual guides have long used psychedelic mushrooms to enhance understanding. Then there are the tiny threads of fungi, called hyphae, that create a communications network for the natural world while decomposing organic matter. Combining engaging and accessible text with beautiful images, The Lives of Fungi lays out all the essential facts about fungi for the mycologically curious.\"-- Provided by publisher.
Book
New Dipyrroloquinones from a Plant-Derived Endophytic Fungus ITalaromyces/I sp
Two new dipyrroloquinones, namely talaroterreusinones A (1) and B (2), together with four known secondary metabolites, terreusinone A (3), penicillixanthone A (4), isorhodoptilometrin (5), and chrysomutanin (6), were isolated from the solid culture of the endophytic fungus Talaromyces sp. by integrating mass spectrometry-based metabolic profiling and a bioassay-guided method. Their planar structures and stereochemistry were elucidated by comprehensive spectroscopic analysis including NMR and MS. The absolute configuration at C-1″ of terreusinone A (1) was established by applying the modified Mosher’s method. Compounds 1–6 were evaluated for anti-inflammatory activity and cytotoxicity. As a result, 1–3 inhibited the LPS-stimulated NO production in macrophage RAW264.7 cells, with IC[sub.50] values of 20.3, 30.7, and 20.6 µM, respectively. Penicillixanthone A (4) exhibited potent cytotoxic activity against Hep G2 and A549 cell lines, with IC[sub.50] values of 117 nM and 212 nM, respectively, and displayed significant antitumour effects in A549 cells by inhibiting the PI3K-Akt-mTOR signalling pathway.
Journal Article
Fungi : mushrooms, toadstools, molds, yeasts, and other fungi
\"Features an examination of the four major groups of fungi: yeasts, toadstools, chytrids, and bread molds\"--P. [4] of cover.
Book
Four Undescribed Pyranones from the IScutellaria formosana/I-Derived Endophytic Fungi IAscomycota/I sp. FAE17
Four undescribed pyranone derivatives, named ascomycopyrones A–D (1–4), as well as one known analogue simplicilopyrone (5) (this is the first study to report the absolute configuration), were isolated from the endophytic fungus Ascomycota sp. FAE17 derived from the flowers of Scutellaria formosa. The structures of these pyranones were identified by comprehensive spectroscopic and MS analyses, and the absolute configurations were determined by their experimental and quantum chemical electronic circular dichroism (ECD) calculations. All isolated compounds were tested for various bioactivities, including antibacterial, cytotoxic activity, and NO inhibitory activity. Unfortunately, none of the compounds showed significant bioactivities.
Journal Article
Identification of pathogenic fungi
\"A fully updated edition of this highly regarded textbook, incorporating new colour photographs of key species and their microscopic features, information on the latest antifungal drugs, and updated taxonomic information. Endorsed by the Health Protection Agency and written by world renowned experts in medical mycology\"--Provided by publisher.
eBook
Meetings with remarkable mushrooms : forays with fungi across hemispheres
\"Meetings with remarkable mushrooms are an all-year event for Australian ecologist Alison Pouliot. Bifurcating her life between the northern and southern hemispheres, she ensures that she experiences two autumns per year and has double the chances to find fungi. In this book, she uses visits around the world to show readers the diversity of this life-and makes the case that appreciating fungi is a key to understanding the power and fragility of our planet. With Pouliot as our guide, we learn that fire-loving truffles in the genus Mesophelia transform their scent after burning-from a sweet nut-like aroma into a stink like rotting onion-to lure mammals that excavate and eat these truffles, and then spread their spores. Or, with her, we spot the eerie glow of the ghost fungus. The ghost fungus looks like an edible oyster mushroom, but don't confuse them. If you put ghost fungus in your mouth, it will soon come back out, with everything else in your stomach. Or you might enjoy seeing vegetable caterpillars-neither vegetable nor caterpillar-but a fungus that eats arthropods from the inside out. Pouliot's focus on the global community of fungus experts, the importance of local knowledge, and the historic and current contributions of women in mycology all reinforce her message that understanding fungi is fundamental for us all\"-- Provided by publisher.
Book
Hydrophobin Gene ICmhyd4/I Negatively Regulates Fruiting Body Development in Edible Fungi ICordyceps militaris/I
A deep understanding of the mechanism of fruiting body development is important for mushroom breeding and cultivation. Hydrophobins, small proteins exclusively secreted by fungi, have been proven to regulate the fruiting body development in many macro fungi. In this study, the hydrophobin gene Cmhyd4 was revealed to negatively regulate the fruiting body development in Cordyceps militaris, a famous edible and medicinal mushroom. Neither the overexpression nor the deletion of Cmhyd4 affected the mycelial growth rate, the hydrophobicity of the mycelia and conidia, or the conidial virulence on silkworm pupae. There was also no difference between the micromorphology of the hyphae and conidia in WT and ΔCmhyd4 strains observed by SEM. However, the ΔCmhyd4 strain showed thicker aerial mycelia in darkness and quicker growth rates under abiotic stress than the WT strain. The deletion of Cmhyd4 could promote conidia production and increase the contents of carotenoid and adenosine. The biological efficiency of the fruiting body was remarkably increased in the ΔCmhyd4 strain compared with the WT strain by improving the fruiting body density, not the height. It was indicated that Cmhyd4 played a negative role in fruiting body development. These results revealed that the diverse negative roles and regulatory effects of Cmhyd4 were totally different from those of Cmhyd1 in C. militaris and provided insights into the developmental regulatory mechanism of C. militaris and candidate genes for C. militaris strain breeding.
Journal Article