Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
85,310
result(s) for
"Gilbert "
Sort by:
Gilbert Simondon's Psychic and collective individuation : a critical introduction and guide
A critical commentary on Simondon's Psychic and collective individuation. This book clarifies Simondon's complex terminology and structure through chapter by chapter commentary. It also invites a dialogue with other thinkers/philosophers and places the work in its historical context. It includes a discussion about Simondon's relevance to current ideas about biopolitics and post-Nietzschean ethics.
Book
Gilbert and Sullivan
In this, the first book to focus on the original cast members of
the classic Gilbert and Sullivan comic operas, world-renowned
musical theater expert Kurt Gänzl provides a concise history of the
writing and production of each opera, vividly colored by the often
little-known life stories of these early performers. Meticulously
researched and lavishly illustrated with rare photographs,
Gilbert and Sullivan: The Players and the Plays delves
into the professional and personal lives of the British and
American actors and singers who created the celebrated \"famous
fourteen\" Gilbert and Sullivan operas.
eBook
Gilbert & George : The general jungle or Carrying on sculpting, late summer 1971 : presented in its entirety, autumn 2017
\"Since 1967, renowned artists Gilbert & George have made themselves into their art, sacrificing their individual identities to devote themselves to a more democratic art practice, which they call 'Art for All.' This catalogue presents their formative early work, The General Jungle or Carrying on Sculpting (1971). Comprised of twenty-three monumental, multi-panel charcoal-on-paper sculptures depicting the artists wandering streets and parks in London and inscribed with philosophical slogans, The General Jungle or Carrying on Sculpting was first exhibited at the Sonnabend Gallery in New York in 1971. Published in conjunction with Lâevy Gorvy's exhibition of the work, this fully illustrated catalogue features a newly commissioned essay by Michael Bracewell based on a recent interview with the artists, an original poem by Kostas Anagnopoulos, newspaper reviews from the inaugural exhibition at the Sonnabend Gallery, and a facsimile of the postal sculpture A Day in the Life of George & Gilbert, the sculptors (1971).\" -- Publisher's description
Book
Magnetic skyrmions on a two-lane racetrack
Magnetic skyrmions are particle-like textures in magnetization, characterized by a topological winding number. Nanometer-scale skyrmions have been observed at room temperature in magnetic multilayer structures. The combination of their small size, topological quantization and their efficient electric manipulation makes them interesting candidates for information carriers in high-performance memory devices. A skyrmion racetrack memory has been suggested, in which information is encoded in the distance between skyrmions moving in a one-dimensional nanostrip. Here, I propose an alternative design where skyrmions move in two (or more) parallel lanes and the information is stored in the lane number of each skyrmion. Such a multilane track can be constructed by controlling the height profile of the nanostrip. Repulsive skyrmion-skyrmion interactions in narrow nanostrips guarantee that skyrmions on different lanes cannot pass each other. Current pulses can be used to induce a lane change, and combining these elements provides a robust, efficient design for skyrmion-based storage devices.
Journal Article
Genetic, clinical, and biochemical profiling of Gilbert syndrome in a Nepali cohort: High prevalence of the UGT1A1 c.-3279T>G polymorphism and correlation with hematological parameters
Gilbert Syndrome (GS) is a common hereditary disorder characterized by intermittent jaundice. The pathogenesis is unconjugated hyperbilirubinemia due to reduced hepatic UDP-glucuronosyltransferase 1A1 (UGT1A1) activity. Its genetic basis relies on c.-3279T > G polymorphism (UGT1A1*60), which reduces gene transcription by approximately 40%, and is highly prevalent in Asian populations.
This study aimed to profile the genetic, biochemical, and clinical characteristics of individuals with clinical features of GS in Nepal and examine correlations between UGT1A1 genotypes and hematological parameters.
This study utilized a prospective descriptive design supplemented by a retrospective review of medical records, including 75 patients with isolated unconjugated hyperbilirubinemia. Prospective recruitment and data collection were conducted from July 18, 2025, to November 30, 2025. Medical records from outside facilities were accessed for research purposes from July 18, 2025, to November 30, 2025, covering records dating back to January 1, 2021. Patients underwent ARMS-PCR genetic testing for the UGT1A1 c.-3279T > G variant.Patients with hemolysis or hepatobiliary disease were excluded. Genetic confirmation of GS was based on the presence of the G allele.
Mean age of cohort was 28.9 ± 10.4 years (range: 14-55), with a male predominance (69.3%). Genotype distribution revealed 66.7% homozygous mutant (G/G), 29.3% heterozygous (G/T), and 4% wild-type (T/T), yielding a G allele frequency of 81.3%. Mean bilirubin levels showed a genotype-phenotype correlation: G/G (4.3 ± 1.1 mg/dL), G/T (3.2 ± 0.9 mg/dL), and T/T (2.4 ± 0.3 mg/dL). Hematological parameters were within normal reference ranges across all genotypes, confirming the non-hemolytic nature of the condition. No hepatosplenomegaly was detected on ultrasonography.
This study demonstrates an exceptionally high prevalence of the UGT1A1*60 G allele among individuals with clinical features of GS in Nepal. These findings reaffirm the benign, non-hemolytic character of GS and underscore the diagnostic and pharmacogenetic utility of UGT1A1 genotyping in the Nepali population.
Journal Article
Norms of inquiry
Epistemologists have recently proposed a number of norms governing rational inquiry. My aim in this paper is to unify and explain recently proposed norms of inquiry by developing a general account of the conditions under which inquiries are rational, analogous to theories such as evidentialism and reliabilism for rational belief. I begin with a reason-responsiveness conception of rationality as responding correctly to possessed normative reasons. I extend this account with a series of claims about the normative reasons for inquiry that we possess. I apply the account to shed light on two classes of norms that have featured prominently in recent discussions: norms of clutter avoidance forbidding agents from engaging in trivial inquiries, and norms of logical non-omniscience governing properties such as the deductive closure and consistency of an agent's belief state. I conclude with a discussion of the sense in which norms of inquiry should be regarded as epistemic norms.
Journal Article
Effect of UDP‐glucuronosyltransferase 1A1 activity on risk for developing Gilbert's syndrome
Variations at the six nucleotides −3279 (T > G), −53 (A[TA]6TAA > A[TA]7TAA), 211 (G > A), 686 (C > A), 1091 (C > T), and 1456 (T > G) in the UDP‐glucuronosyltransferase 1A1 (UGT1A1) gene were determined in 178 Taiwanese patients with Gilbert's syndrome and in 200 healthy adults. Every subject was classified as a genotype depending on variation status of the six nucleotides in the UGT1A1 gene. The UGT1A1 activity for each genotype was calculated and then those genotypes were divided into 10 subgroups (Q1~Q10) according to their UGT1A1 activities, by using 10% as an interval. There were 24 genotypes observed, with UGT1A1 activity ranged 9%~100% of normal. There were two and six subjects with Gilbert's syndrome and none of healthy controls carrying genotypes in the Q1 and Q2 subgroups, respectively. The odds of developing Gilbert's syndrome were significantly higher for subjects carrying genotypes in the Q3, Q4, and Q5 subgroups than for those with genotype in the Q10 subgroup (odds ratios: 240.22, 59.80, and 14.67, respectively, P < .001 for each). Among the 178 patients of Gilbert's syndrome, serum bilirubin value was inversely correlated with UGT1A1 activity (r = −.306, P < .001). The sensitivity was 72.0% and the specificity was 90.5% by using UGT1A1 activity ≦40% of normal as the cut‐off point to distinguish between healthy subjects and patients of Gilbert's syndrome. Our results demonstrate that UGT1A1 activity is certainly a determinate for serum bilirubin value and UGT1A1 activity ≦40% of normal is a proper risk factor for the development of Gilbert's syndrome.
Journal Article