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result(s) for
"Glyphosate"
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Toxic legacy : how the weedkiller glyphosate is destroying our health and the environment
\"The Silent Spring of our time From an MIT scientist, mounting evidence that the active ingredient in the world's most commonly used weedkiller is responsible for debilitating chronic diseases, including cancer, liver disease, and more Glyphosate is the active ingredient in Roundup, the most commonly used weedkiller in the world. Nearly 300 million pounds of glyphosate-based herbicide are sprayed on farms-and food-every year. Agrichemical companies claim that glyphosate is safe for humans, animals, and the environment. But emerging scientific research on glyphosate's deadly disruption of the gut microbiome, its crippling effect on protein synthesis, and its impact on the body's ability to use and transport sulfur-not to mention several landmark legal cases- tells a very different story. In Toxic Legacy, MIT senior research scientist Stephanie Seneff, PhD presents stunning evidence based on countless published, peer-reviewed studies that glyphosate plays a major role in skyrocketing rates of chronic diseases, including cancer, gut dysbiosis, non-alcoholic fatty liver disease, autism, infertility, and more. Dr. Seneff describes glyphosate's unique mechanism of toxicity that slowly erodes human health over time, as well as its impact on soil, ecosystems, and the nutritional quality of the nation's food supply. As Rachel Carson did with DDT in the 1960's, Stephanie Seneff sounds the alarm on glyphosate, giving you essential information to protect your health, your family's health, and the planet on which we all depend\"-- Provided by publisher.
Wiper Application of Herbicides to ICirsium arvense/I
2022
Wiper applicators allow herbicides to be selectively delivered to upright target weeds, thereby avoiding application to nearby lower-growing desirable pasture plants. In this research, we investigated the efficacy of wiper application of four herbicides, clopyralid, metsulfuron, glyphosate and a triclopyr/picloram mixture, to control Cirsium arvense (L.) Scop., a troublesome weed of pastures in New Zealand. The results showed that wiper application of herbicides was a useful technique for controlling C. arvense. In one trial when plants were treated at the post-flowering stage, stem density reductions in the following season of 93%, 90% and 82% were achieved following a double pass with a rotary weed wiper containing glyphosate, clopyralid and metsulfuron, respectively. A double pass gave better control of dense infestations of C. arvense than a single pass for glyphosate and triclopyr/picloram, but not for clopyralid and metsulfuron. Despite wiper applicators usually being selective, some damage to pastures was recorded, very likely due to rain falling soon after wiper application. Overall, the results of this study revealed that wiper application can be used to selectively control C. arvense when the plants are treated at the post-flowering stage, though only if plants are actively growing. In addition, among the herbicides tested, glyphosate appears to be the best choice when using weed wipers to manage C. arvense, as this herbicide caused the least damage to pasture plants if washed off afterwards by rain.
Journal Article
An ABCC-type transporter endowing glyphosate resistance in plants
by
Pan, Lang
,
Han, Heping
,
Maguza, Anna
in
Agricultural land
,
Agricultural Sciences
,
Agrochemicals
2021
Glyphosate is the most widely used herbicide in world agriculture and for general vegetation control in a wide range of situations. Global and often intensive glyphosate selection of very large weedy plant populations has resulted in widespread glyphosate resistance evolution in populations of many weed species. Here, working with a glyphosate-resistant (GR) Echinochloa colona population that evolved in a Western Australia agricultural field, we identified an ATP-binding cassette (ABC) transporter (EcABCC8) that is consistently up-regulated in GR plants. When expressed in transgenic rice, this EcABCC8 transporter endowed glyphosate resistance. Equally, rice, maize, and soybean overexpressing the EcABCC8 ortholog genes were made resistant to glyphosate. Conversely, CRISPR/Cas9-mediated knockout of the EcABCC8 ortholog gene OsABCC8 increased rice susceptibility to glyphosate. Subcellular localization analysis and quantification of glyphosate cellular levels in treated ABCC8 transgenic rice plants and isolated leaf protoplasts as well as structural modeling support that EcABCC8 is likely a plasma membrane–localized transporter extruding cytoplasmic glyphosate to the apoplast, lowering the cellular glyphosate level. This is a report of a membrane transporter effluxing glyphosate in a GR plant species, and its function is likely conserved in crop plant species.
Journal Article
Chronique de droit de l’Union européenne des pollutions et nuisances
by
Chevalier, Émilie
in
Glyphosate
2021
Les arrêts rendus par la Cour de justice de l’Union européenne en 2020 et portant sur les pollutions et nuisances s’inscrivent d’abord dans une lignée constante depuis quelques années, soit le rappel à l’ordre des États membres quant à leurs obligations découlant des législations européennes relatives à la qualité de l’air ou de l’eau. Ils rendent également compte d’enjeux plus innovants, en révélant la complexité des processus décisionnels au sein de l’espace administratif européen, spécialement lorsqu’ils interviennent sur des sujets sensibles, tels que le glyphosate, en rendant en même temps l’accès au juge incertain pour garantir la légalité de l’action européenne et nationale en la matière. The rulings of the ECJ in 2020 concerning pollution and nuisances follow, first of all, a constant path of cases over the last few years, i.e. recalling Member States to comply with their obligations under European legislation on air or water quality. There are also more innovative issues, showing the complexity of decision-making process within the European administrative space, especially when it deals with sensitive issues such as glyphosate, while at the same time making access to the courts uncertain in order to guarantee the legality of European and national action in this area.
Journal Article
DROIT EUROPÉEN. Accès à la justice
by
CHEVALIER, Émilie
in
Glyphosate
2021
Mise sur le marché des produits phytosanitaires. Renouvellement de l’approbation de la substance active « glyphosate ». Qualité pour agir d’une entité régionale. Affectation directe. CJUE, 3 décembre 2020, Région de Bruxelles-Capitale c. Commission, C-352/19 P.
Journal Article
A ratiometric fluorescence and colorimetry dual-signal sensing strategy based on o-phenylenediamine and AuNCs for determination of Cu.sup.2+ and glyphosate
2024
A ratiometric fluorescence sensing strategy has been developed for the determination of Cu.sup.2+ and glyphosate with high sensitivity and specificity based on OPD (o-phenylenediamine) and glutathione-stabilized gold nanoclusters (GSH-AuNCs). Water-soluble 1.75-nm size GSH-AuNCs with strong red fluorescence and maximum emission wavelength at 682 nm were synthesized using GSH as the template. OPD was oxidized by Cu.sup.2+, which produced the bright yellow fluorescence oxidation product 2,3-diaminophenazine (DAP) with a maximum fluorescence emission peak at 570 nm. When glyphosate existed in the system, the chelation between glyphosate and Cu.sup.2+ hindered the formation of DAP and reduced the fluorescence intensity of the system at the wavelength of 570 nm. Meanwhile, the fluorescence intensity at the wavelength of 682 nm remained basically stable. It exhibited a good linear relationship towards Cu.sup.2+ and glyphosate in water in the range 1.0-10 µM and 0.050-3.0 µg/mL with a detection limit of 0.547 µM and 0.0028 µg/mL, respectively. The method was also used for the semi-quantitative determination of Cu.sup.2+ and glyphosate in water by fluorescence color changes visually detected by the naked eyes in the range 1.0-10 µM and 0.30-3.0 µg/mL, respectively. The sensing strategy showed higher sensitivity, more obvious color changes, and better disturbance performance, satisfying with the detection demands of Cu.sup.2+ and glyphosate in environmental water samples. The study provides a reliable detection strategy in the environment safety fields. Graphical abstract
Journal Article
Vers un élargissement de l'accès à l'information sur les risques sanitaires liés à l'environnement en droit de l'Union européenne
by
JAMAY, Florence
in
Glyphosate
2020
Alors que, dans le cadre du contentieux relatif au glyphosate, la Commission et l’EFSA ont refusé à plusieurs reprises l’accès aux études fondant l’autorisation de mise sur le marché de la substance, le juge de l’Union a fait une interprétation large de la notion d’informations relatives à des émissions dans l’environnement pour permettre leur communication. Les carences que ce contentieux a révélées ont en outre suscité une réforme de l’évaluation des risques afin de renforcer sa transparence et son indépendance.
Journal Article
Glyphosate Interference in Follicular Organization in the Wall Lizard IPodarcis siculus/I
2023
Glyphosate (Gly) is a broad-spectrum herbicide widely used thanks to its high efficiency and low toxicity. However, evidence exists of its toxic effects on non-target organisms. Among these, the animals inhabiting agricultural fields are particularly threatened. Recent studies demonstrated that exposure to Gly markedly affected the morphophysiology of the liver and testis of the Italian field lizard Podarcis siculus. The present study aimed to investigate the effects of the herbicide on the female reproductive system of this lizard in order to have a full picture of Gly-induced reproductive impairment. The animals were exposed to 0.05 and 0.5 μg/kg of pure Gly by gavage for 3 weeks. The results demonstrated that Gly, at both doses tested, profoundly interfered with ovarian function. It induced germ cells' recruitment and altered follicular anatomy by anticipating apoptotic regression of the pyriform cells. It also induced thecal fibrosis and affected oocyte cytoplasm and zona pellucida organizations. At the functional levels, Gly stimulated the synthesis of estrogen receptors, suggesting a serious endocrine-disrupting effect. Overall, the follicular alterations, combined with those found at the level of the seminiferous tubules in males, suggest serious damage to the reproductive fitness of these non-target organisms, which over time could lead to a decline in survival.
Journal Article