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"Hair Preparations"
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Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
Persistent hair loss is a major cause of psychological distress and compromised quality of life in millions of people worldwide. Remarkable progress has been made in understanding the molecular basis of hair loss and identifying valid intracellular targets for designing effective therapies for hair loss treatment. Whereas a variety of growth factors and signaling pathways have been implicated in hair cycling process, the activation of Wnt/β-catenin signaling plays a central role in hair follicle regeneration. Several plant-derived chemicals have been reported to promote hair growth by activating Wnt/β-catenin signaling in various in vitro and in vivo studies. This mini-review sheds light on the role of Wnt/β-catenin in promoting hair growth and the current progress in designing hair loss therapies by targeting this signaling pathway.
Journal Article
Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid
Kidney Injury and Hair Straightening with Glyoxylic AcidThis letter describes a woman with recurrent episodes of acute kidney injury due to oxalate nephropathy after hair-straightening procedures and provides evidence that glyoxylic acid is responsible.
Journal Article
Smashie McPerter and the mystery of the missing goop
\"When the third-graders of Room 11 learn that they all must take part in a musicale, Smashie can't wait to sing something heartfelt and loud. But the others are not so eager. Luckily, Charlene s mom has agreed to donate her special gel that lengthens and sculpts hair into shapes (from a musical note to a roller skate), and soon, with the help of some retro sixties go-go dancing, all the kids are raring to go. That is, until their jars of goop go missing! Who would steal their beloved Herr Goop, and why? Time for Smashie and her best friend, Dontel, to get out their Investigation Notebooks! Discussions of motives and perps, hasty mis-accusations and apology brownies, a math lesson used to crack a mysterious code, and more than a few choice red herrings build up to a truly hilarious madcap finale.\"--Provided by publisher.
Book
Botanical Extract–Infused Shampoo and Hair Tonic for Hair Loss in Androgenetic Alopecia: A TREND‐Compliant, Prospective Single‐Arm Preexperimental Study
Background Androgenetic alopecia (AGA) is the most prevalent form of hair loss, often leading to treatment discontinuation due to the adverse effects and perceived ineffectiveness of conventional treatments. Botanical extracts are gaining attention for their potential benefits in managing AGA with minimal side effects. Aims To evaluate the efficacy and safety of a shampoo and hair tonic containing Asacurin100, a botanical extract blend, in improving hair loss conditions in patients with AGA. Methods A prospective single‐group, pretest–posttest study was conducted with 35 male participants diagnosed with AGA at a Korean medicine clinic. Participants applied the shampoo once daily and the hair tonic two to three times daily for 6 months. Data were collected via standardized global scalp photographs and a custom‐designed questionnaire assessing scalp symptoms. Statistical analyses were performed to evaluate changes in hair loss area and subjective symptoms. Results The study observed reductions in hair loss area, with a mean decrease of −27.35 ± 26.31 (p < 0.0001), and improvement in all scalp symptom scores. The Patient Global Impression of Change (PGIC) revealed that 80% of participants reported “much” or “very much” improvement in hair condition. No serious adverse events were reported. Conclusions The findings suggest that botanical extract–infused shampoo and hair tonic are effective and well‐tolerated treatments for AGA, reducing hair loss and enhancing scalp health. The results warrant further investigation through larger randomized controlled trials to validate the efficacy of plant‐derived compounds for AGA.
Journal Article
Black like you : an autobiography
\"Herman Mashaba rose from humble beginnings to become one of South Africa's wealthiest and best-known entrepreneurs, and mayor of Africa's most important city.\"--Back cover.
Book
Chemical/straightening and other hair product usage during childhood, adolescence, and adulthood among African-American women: potential implications for health
Few studies have characterized life course hair product usage beyond ever/never. We investigated hair product use from childhood to adulthood, usage patterns in adulthood, and socioeconomic status (SES) correlates among African-American (AA) women. Using self-reported data from 1555 AA women enrolled in the Study of Environment, Lifestyle, and Fibroids (2010–2018), we estimated the usage frequency of chemical relaxer/straightener (≥twice/year, once/year, and rarely/never) and leave-in/leave-on conditioner (≥once/week, 1–3 times/month, and rarely/never) during childhood, adolescence, and adulthood. Latent class analysis was used to identify patterns of adulthood usage of multiple hair products. SES was compared across latent classes. With a mean age of 33 ± 3.4 years, most women reported ever using chemical relaxers/straighteners (89%), and use ≥twice/year increased from childhood (9%) to adolescence (73%) but decreased in adulthood (29%). Leave-in/leave-on conditioner use followed the same pattern. Each of three identified latent classes reported frequent styling product use and infrequent relaxer/straightener use. Class One was unlikely to use any other products, Class Two moderately used shampoo and conditioner, and Class Three frequently used multiple product types (e.g., moisturizers and conditioners). Participants in the latter two classes reported higher SES. Ever/never characterization may miss important and distinctive patterns of hair product use, which may vary by SES.
Journal Article
Madam C.J. Walker : the woman behind hair care products for African Americans
\"Why is Madam C.J. Walker important? She invented a brand of hair care products just for African Americans! Follow her journey from the cotton fields to a seat at the millionaires' table. It's a story of big dreams, hard work, and life-changing inventions!\"--Page 4 of cover.
Book
Application of Alkyl Polyglucosides as Components of the Extraction Medium in the Preparation of a Shampoo Cosmetic Formulation Containing Substances Isolated from Red Grape Pomace
This study highlights the use of alkyl polyglucosides (APGs) as sustainable and mild surfactants in cosmetic preparations, such as shampoos, following the principles of green chemistry and environmentally friendly development. APGs are non-ionic surfactants of plant origin. Their favorable dermatological and toxicological profile, as well as their high skin compatibility, make them an excellent alternative to conventional surfactants used in cosmetic products. To increase the sustainability and functionality of cosmetic preparations, the concept of loan extraction was applied, in which the extraction medium is borrowed from the final cosmetic formulation. After the extraction process, the medium enriched with the extracted compounds is returned to the cosmetic. The APGs, as part of cosmetic formulations, were used in the micellar extraction process of grape pomace, a by-product of wine production. The study evaluated the effect of different types of APGs—coco-glucoside and decyl glucoside—and their concentrations on extraction efficiency, measured by LC-MS/MS based on the content of phenolic compounds and amino acids, as well as the total phenolic content, total anthocyanin content and antioxidant activity assessed by UV-Vis spectroscopy. The designed extraction medium was then used to develop a shampoo, which showed a significantly lower zein value compared to the reference preparation without extract, indicating a reduced skin irritation potential. These results highlight the potential of APG in the development of milder, sustainable cosmetic products with the ability to extract bioactive components, supporting their use in the production of environmentally friendly cosmetics.
Journal Article