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According to the International Air Transport Association, the industry fuel bill accounts for more than 25% of the annual airline operating costs. In times of severe economic constraints and increasing fuel costs, air carriers are looking for ways to reduce costs and improve fuel efficiency without putting flight safety into jeopardy. In particular, this is inducing discussions on how much additional fuel to put in a planned route to avoid diverting to an alternate airport due to Air Traffic Flow Management delays. We provide here a general model to support such decisions. We illustrate it with a case study and provide comparison with the current practice, showing the relevance of our approach.