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result(s) for
"ILCR"
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The Health Risk and Source Assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in the Soil of Industrial Cities in India
2023
Industrial areas play an important role in the urban ecosystem. Industrial site environmental quality is linked to human health. Soil samples from two different cities in India, Jamshedpur and Amravati, were collected and analyzed to assess the sources of polycyclic aromatic hydrocarbons (PAHs) in industrial areas and their potential health risks. The total concentration of 16 PAHs in JSR (Jamshedpur) varied from 1662.90 to 10,879.20 ng/g, whereas the concentration ranged from 1456.22 to 5403.45 ng/g in the soil of AMT (Amravati). The PAHs in the samples were dominated by four-ring PAHs, followed by five-ring PAHs, and a small percentage of two-ring PAHs. The ILCR (incremental lifetime cancer risk) of the soil of Amravati was lower compared to that of Jamshedpur. The risk due to PAH exposure for children and adults was reported to be in the order of ingestion > dermal contact > inhalation while for adolescents it was dermal contact > ingestion > inhalation in Jamshedpur. In contrast, in the soil of Amravati, the PAH exposure path risk for children and adolescents were the same and showed the following order: dermal contact > ingestion > inhalation while for the adulthood age group, the order was ingestion > dermal contact > inhalation. The diagnostic ratio approach was used to assess the sources of PAHs in various environmental media. The PAH sources were mainly dominated by coal and petroleum/oil combustion. As both the study areas belong to industrial sites, the significant sources were industrial emissions, followed by traffic emissions, coal combustion for domestic livelihood, as well as due to the geographical location of the sampling sites. The results of this investigation provide novel information for contamination evaluation and human health risk assessment in PAH-contaminated sites in India.
Journal Article
Health risk assessment for carcinogenic and non-carcinogenic heavy metal exposures from vegetables and fruits of Bangladesh
Most popular vegetables and fruits and their corresponding soil from the sub-urban industrial area of Bangladesh were collected and the concentration of carcinogenic (Pb, As, and Cd) and non-carcinogenic (Fe, Co, V, Cu, Cr, Zn, Mn, and Ni) heavy metals was determined. Health risk was evaluated by estimating daily heavy metal intake and computing cancer and non-cancer risks (ILCR and THQ) using probabilistic risk assessment model of US-EPA. Heavy metals in vegetables varied with vegetable species as well as metal types. Higher daily intake of As, Fe, Mn, and Pb was observed from the consumption of root and leafy vegetables. Moreover, the probability of an adult for developing cancer from the consumption of studied vegetables was greater than US-EPA threshold risk limit (>10−4) for As and Cd. In addition, cumulative cancer risk (∑ILCR) of all the studied vegetables and fruits exceeded the limit for fruit, root, leafy vegetables, and fruits (22, 15, 59, and 4%) with As, Cd, and Pb as 17, 81, and 2%, respectively. Non-cancer risk index also presented Pb, As, Mn, and Fe as the dominant contaminants of root and leafy vegetables that contributed 80–90% of HI. It suggests that the study area is unsuitable for growing leafy and root vegetables due to the risk of higher intakes of heavy metals which affect food safety. Mn, Pb, Fe, and As are the most predominant heavy metals posing non-cancer risk while Cd caused the highest cancer risk.
Journal Article
Source-specific probabilistic health risk assessment of potentially toxic elements in groundwater of a copper mining and smelter area
by
Nastasović, Aleksandra
,
Miletić, Andrijana
,
Tadić, Tamara
in
Anthropogenic factors
,
Body weight
,
Cadmium
2024
The occurrence of potentially toxic elements (PTEs), including twelve heavy metal(loid)s (Cd, Cr, Cu, Ni, Pb, Zn, Hg, As, Co, V, Fe, Mn), fluoride (F−), and nitrate (NO3−) was evaluated in groundwater in the copper mining and smelter area of Bor city (south Carpathian, eastern Serbia). Groundwater samples were analyzed to determine the extent of pollution, identify natural and anthropogenic input of PTEs, and estimate potential human health risks due to exposure to these substances. The results revealed that the groundwater in the study area was highly contaminated with PTEs, particularly Cu and Zn. Multivariate analysis supported the natural and anthropogenic origin of PTEs, with Fe, Mn, and F− classified as naturally occurring, NO3− resulting from agricultural activities, while other PTEs were linked to smelter/mining processes. Geospatial mapping discovered several hotspots with potential high non-cancer and cancer risks to humans through ingestion pathway. From the studied PTEs, As is the most health risk contributing toxic element. The source-specific probabilistic risk assessment indicated the most significant contribution to the hazard index and total cancer risk from accidental leakage of metallurgical wastewater and wastewater from open mine pits. Monte Carlo analysis identified the human body weight and the ingestion rate as the most sensitive risk parameters. The study underscores the need for stringent environmental management measures, emphasizing the critical role of source-specific risk assessments in mitigating potential hazards associated with metallurgical wastewater and open mine pits.
Journal Article
Analysis and probability health risk assessment of phthalate acid esters (PAEs) in ice cream and cream samples consumed in Tehran, Iran
by
Shariatifar, Nabi
,
Moazzen, Mojtaba
,
Khodaei, Seyedeh Mahsa
in
Bis (2-ethylhexyl) phthalate (DEHP)
,
CDI (Chronic Daily Intake)
,
dairy products
2026
In this research, the MSPE-GC/MS method was applied to measure the concentrations of six PAEs (phthalate acid esters) in ice cream and cream samples, and a risk assessment was also performed using the MCS method. The mean concentrations of ∑PAEs and DEHP (in all samples) were 7.082 ± 2.845 and 2.067 ± 0.629 µg/L, respectively (that were below the standard levels). The carcinogenic risk’s results for DEHP revealed no carcinogenic effects were posed by the consumption of ice cream (7.78 × 10−6) and cream (1.16 × 10−5) for adults, while there was a negligible risk for children by the consumption of ice cream (1.09 × 10−4) and cream (1.62 × 10−4). The findings revealed the total noncarcinogenic risk (TTHQ) of PAE compounds for adults and children was <1. While the current study demonstrates the levels of PAEs in samples are within safe limits according to existing standards, it is crucial to recognize the broader implications of PAE exposure in food products.
Journal Article
An extensive investigation on human risk associated with PAHs in fish and sediment in Bushehr, Northern of Persian Gulf
by
Jaafarzadeh Haghighi Fard, Neamat
,
Pazira, Abdul Rahim
,
Kohgardi, Esmaeil
in
692/499
,
704/158
,
704/172
2024
Here, a comprehensive study was designed to estimate the human risk assessment attributed to exposure of polycyclic aromatic hydrocarbons (PAHs)in sediment and fish in most polluted shore area in north of Persian Gulf. To this end, a total of 20 sediment and inhabitual Fish, as one of most commercial fish, samples were randomly collected from 20 different stations along Bushehr Province coastline. The 16 different components of PAHs were extracted from sediment and edible parts of inhabitual fish and measured with high-performance liquid chromatography (HPLC) and gas chromatography (GC), respectively. In addition, dietary daily intake (DDI) values of PAHs via ingestion Indian halibut and the incremental lifetime cancer risk (ILCR) attributed to human exposure to sediments PAHs via (a) inhalation, (b) ingestion, and (c) dermal contact for two groups of ages: children (1–11 years) and adults (18–70 years) were estimated. The results indicated that all individual PAHs except for Benzo(b)flouranthene (BbF) and Benzo(ghi) perylene (BgP) were detected in different sediment sample throughout the study area with average concentration between 2.275 ± 4.993 mg.kg
–1
dw. Furthermore, Naphthalene (Nap) with highest average concentration of 3.906 ± 3.039 mg.kg
–1
dw was measured at the Indian halibut. In addition, the human risk analysis indicated that excess cancer risk (ECR) attributed to PAHs in sediment and fish in Asaluyeh with high industrial activities on oil and derivatives were higher the value recommended by USEPA (10
−6
). Therefore, a comprehensive analysis on spatial distribution and human risk assessment of PAHs in sediment and fish can improve the awareness on environmental threat in order to aid authorities and decision maker to find a sustainable solution.
Journal Article
Polycyclic Aromatic Hydrocarbons in Indoor Dust in Croatia: Levels, Sources, and Human Health Risks
by
Dvoršćak, Marija
,
Jakovljević, Ivana
,
Klinčić, Darija
in
Adult
,
Air Pollutants - analysis
,
Cancer
2022
Compounds that contribute to indoor pollution are regularly investigated due to the fact that people spend most of their time indoors. Worldwide investigations have shown that polycyclic aromatic hydrocarbons (PAHs) are present in indoor dust, but to the best of our knowledge, this paper reports for the first time the presence of PAHs in Croatian households. Eleven PAHs were analysed in house dust samples collected in the city of Zagreb and surroundings (N = 66). Their possible indoor sources and the associated health risks were assessed. Total mass fraction of detected PAHs ranged from 92.9 ng g−1 to 1504.1 ng g−1 (median 466.8 ng g−1), whereby four-ring compounds, Flu and Pyr, contributed the most. DahA was the only compound that did not show statistically significantly positive correlation with other analysed PAHs, indicating that it originated from different sources. Based on diagnostic ratios and principal component analysis (PCA), mixed sources contributed to PAHs levels present in Croatian households. Although our results indicate that Croatian house dusts are weakly polluted with PAHs, total ILCR values calculated for children and adults revealed that people exposed to the highest mass fractions of PAHs measured in this area are at elevated cancer risk.
Journal Article
Comparative Analysis of Polycyclic Aromatic Hydrocarbons and Halogenated Polycyclic Aromatic Hydrocarbons in Different Parts of Perilla frutescens (L.) Britt
2022
Perilla frutescens (L.) Britt., a medicinal herb and edible plant, is very popular among East Asian countries. The perilla leaves, stems and seeds can be used as traditional medicines and foods. Polycyclic aromatic hydrocarbons (PAHs) and halogenated PAHs (HPAHs) are organic pollutants that are widely present in the environment, such as in water, air and soil, and are harmful to humans. In this study, the contents of 16 PAHs and 4 HPAHs in perilla leaves, stems and seeds were determined by gas chromatography tandem mass spectrometry (GC-MS). A total of 12 PAHs were detected in all samples, and no HPAHs were detected. The total contents of PAHs in perilla leaves, stems and seeds varied from 41.93 to 415.60 ng/g, 7.02 to 51.52 ng/g and 15.24 to 180.00 ng/g, respectively. The statistical analyses showed that there were significant differences in the distribution of PAHs in perilla leaves, stems and seeds. On the basis of the toxic equivalent quantity (TEQ) and incremental lifetime cancer risk (ILCR) model, the cancer risks of the intake of perilla leaves, stems and seeds were assessed to be from 3.30 × 10−8 to 2.11 × 10−5, 5.52 × 10−9 to 5.50 × 10−8 and 1.20 × 10−8 to 1.41 × 10−7, respectively. These were lower than 10−4 (the priority risk level of the EPA) and suggested that there may be almost no cancer risk from the intake of these traditional Chinese medicines (TCMs).
Journal Article
Polycyclic aromatic hydrocarbons in road dusts of a densely populated African city: spatial and seasonal distribution, source, and risk assessment
by
Odediran, Emmanuel Toluwalope
,
Adeniran, Jamiu Adetayo
,
Yusuf, Rafiu Olasunkanmi
in
Adults
,
Anthracene
,
anthracenes
2022
Road dust is a principal source and depository of polycyclic aromatic hydrocarbons (PAHs) in many urban areas of the world. Hence, this study probed the spatial and seasonal pattern, sources, and related cancer health risks of PAHs in the road dusts sampled at ten traffic intersection (TIs) of a model African city. Mixed PAHs sources were ascertained using the diagnostic ratios and positive matrix factorization (PMF) model. The results showed fluctuations in mean concentrations from 36.51 to 43.04 µg/g. Three-ring PAHs were the most abundant PAHs with anthracene (Anth) ranging from 6.84 ± 1.99 to 9.26 ± 4.42 µg/g being the predominant pollutant in Ibadan. Benzo(k)Fluoranthene (BkF) which is a pointer of traffic emission was the most dominant among the seven carcinogenic PAHs considered, varying from 2.68 ± 0.43 to 4.59 ± 0.48 µg/g. Seasonal variation results showed that PAH concentrations were 20% higher during dry season than rainy season. The seven sources of PAHs identified by PMF model include the following: diesel vehicle exhausts, gasoline combustion, diesel combustion, coal tar combustion, gasoline vehicle exhausts, coal and wood (biomass) combustion, and emissions from unburnt fossil fuels. Employing the incremental lifetime cancer risk (ILCR) model, the city’s cancer risk of 5.96E-05 for children and 6.60E-05 for adults were more than the satisfactory risk baseline of ILCR ≤ 10
−6
and higher in adults than in Children.
Journal Article
Source appointment and health risk assessment of polycyclic aromatic hydrocarbons in paddy grain from Thailand and Laos
by
Deelaman, Woranuch
,
Choochuay, Chomsri
,
Pongpiachan, Siwatt
in
Adult
,
agricultural wastes
,
Aquatic Pollution
2023
Rice is a staple meal for the majority of Asians. However, human exposure to polycyclic aromatic hydrocarbons from paddy grain is largely unknown in Thailand and Laos. Therefore, information on the quantitative measurement and assessment of the health problems caused by PAHs was analyzed. The results showed that the concentrations of total PAHs in paddy grain in Thailand and Laos were 38.86 ± 5.13 and 11.35 ± 1.96 ng g
−1
, respectively. The highest concentration of PAHs in Thailand was B[k]F, whereas D[a,h]A was found to be the highest in Laos. A
p
-value less than 0.05 was defined, which showed B[b]F and B[k]F from Thailand and Laos were significant, which indicated that they could be from a different pollutant source. The main finding of this study, which was supported by the diagnostic ratios of PAHs and HCA, was that the primary source of PAHs was assumed to be incomplete combustion of petroleum products, which was caused by the burning of industrial fuels or vehicle exhausts, as well as open burning. The findings suggest that these two nations have similar PAH origins. Agricultural waste burning and transportation emissions are well-known sources of PAHs in Thailand and Laos. The cancer risk assessment method was based on the accumulation of PAHs from paddy grains. An ILCR of 1.0E-06 to 1.0E-04 was considered a tolerable limit of cancer risk, while a risk > 1.0E-04 was considered a concern in terms of cancer risk. The findings indicated that while PAH emissions exist, their contribution to global toxicity may be anticipated to be low in inhalation exposure. The higher values of ingestion and dermal risk estimated were regarded as the tolerable limit of cancer risk in children and adults from both countries, indicating that cancer risk in both nations falls within the “acceptable level” range.
Journal Article
The health risks of citizens due to PM2.5 exposure in Ha Noi, Vietnam
2023
A cancerous and non-cancerous risk assessment for PM2.5 exposure is essential, especially in developing children. PM2.5 was determined in concentrations in the Hanoi area both inside and outside the house according to 2019 data before the Covid epidemic, and the health impact assessment was performed for each subject according to the US. Research has also shown that the distribution of indoor PM2.5 concentration data in Hanoi has been determined according to the Weibull with a shape parameter is 8,695 and a scale parameter is 3,695. The average daily indoor PM2.5 concentration at four houses was higher than 20 μg/m3 higher than the warning of WHO guidelines. However, the average concentration on some days exceeded the threshold of Vietnam’s standard. Meanwhile at K3, due to its location in the old town, the PM2.5 concentration is quite stable during the day and at a higher level than in other locations. Therefore, the effect of PM pollution in city houses is necessary for concern, monitoring and solving. This problem is not only present in Vietnam, this is the same in other countries such as some other research. So need to have guidelines when building new houses and inform citizens.
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