Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
1,429,043
result(s) for
"Infections"
Sort by:
The case of the sneezy popcorn : Annie Biotica solves respiratory system disease crimes
\"Learn about strep throat, Hantavirus, whooping cough, Pneumonia, and the differences between the cold and the flu. Then try to guess the disease in three different cases\"-- Provided by publisher.
Book
Untimely interventions
As atrocity has become characteristic of modern history, testimonial writing has become a major twentieth-century genre. Untimely Interventions relates testimonial writing, or witnessing, to the cultural situation of aftermath, exploring ways in which a culture can be haunted by its own history.
Ross Chambers argues that culture produces itself as civilized by denying the forms of collective violence and other traumatic experience that it cannot control. In the context of such denial, personal accounts of collective disaster can function as a form of counter-denial. By investigating a range of writing on AIDS, the First World War, and the Holocaust, Chambers shows how such writing produces a rhetorical effect of haunting, as it seeks to describe the reality of those experiences culture renders unspeakable.
Ross Chambers is Professor of Romance Languages at the University of Michigan. His other books includeFacing It: AIDS Diaries and the Death of the Author.
eBook
Manual of infection prevention and control
\"It has been estimated that in developed countries up to 10% of hospitalized patients develop infections every year. Not only is there a substantial cost to healthcare systems, but some healthcare associated infections (HCIAs) can be fatal. Since the majority of HCIAs are preventable, reducing HCIAs is now considered to be an integral part of patient safety and quality of care provided by all healthcare institutions worldwide. Unlike other books on infection control, the main strength of this book is to provide clear, up-to-date and practical guidance in infection control in an easy to read format which can act as a quick source of reference on all aspects of HCIA for healthcare workers who are either directly or indirectly involved in prevention and control of HCIAs. Although the book's main audience is infection control practitioners such as doctors, nurses, public health physicians, it is also a valuable reference for environmental health officers, health educators, practice managers in GP surgeries, and health service managers\"-- Provided by publisher.
Book
Myocarditis and inflammatory cardiomyopathy: current evidence and future directions
Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the myocardium and a high risk of deteriorating cardiac function, has a heterogeneous aetiology. Inflammatory cardiomyopathy is predominantly mediated by viral infection, but can also be induced by bacterial, protozoal or fungal infections as well as a wide variety of toxic substances and drugs and systemic immune-mediated diseases. Despite extensive research, inflammatory cardiomyopathy complicated by left ventricular dysfunction, heart failure or arrhythmia is associated with a poor prognosis. At present, the reason why some patients recover without residual myocardial injury whereas others develop dilated cardiomyopathy is unclear. The relative roles of the pathogen, host genomics and environmental factors in disease progression and healing are still under discussion, including which viruses are active inducers and which are only bystanders. As a consequence, treatment strategies are not well established. In this Review, we summarize and evaluate the available evidence on the pathogenesis, diagnosis and treatment of myocarditis and inflammatory cardiomyopathy, with a special focus on virus-induced and virus-associated myocarditis. Furthermore, we identify knowledge gaps, appraise the available experimental models and propose future directions for the field. The current knowledge and open questions regarding the cardiovascular effects associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are also discussed. This Review is the result of scientific cooperation of members of the Heart Failure Association of the ESC, the Heart Failure Society of America and the Japanese Heart Failure Society.
Journal Article
The Culture of AIDS in Africa
This book enters into the many worlds of expression brought forth across Africa by the ravaging presence of HIV/AIDS. Africans and non-Africans, physicians and social scientists, journalists and documentarians share here a common and essential interest in understanding creative expression in crushing and uncertain times. Chapters investigate and engage the social networks, power relationships, and cultural structures that enable the arts to convey messages of hope and healing, and of knowledge and good counsel to the wider community. And from Africa to the wider world, the text here brings intimate, inspiring portraits of the performers, artists, communities, and organizations that have shared here their insights and the sense they have made of their lives and actions from deep within this devastating epidemic. Covering the wide expanse of the African continent, the chapters include explorations of, for example, the use of music to cope with AIDS; the relationship between music, HIV/AIDS, and social change; visual approaches to HIV literacy; radio and television as tools for “edutainment”; several individual artists’ confrontations with HIV/AIDS; various performance groups’ response to the epidemic; combating HIV/AIDS with local cultural performance; and more. Source material, such as song lyrics and interviews, weaves throughout the collection, which is a nuanced and profoundly affective portrayal of the intricate relationship between HIV/AIDS and the arts in Africa.
eBook
Discovering retroviruses : beacons in the biosphere
When invading a host cell, viruses seize cell machinery to make copies of their own genes. The immune system recognizes the invasion. In contrast, retroviruses colonize host cells through the process of reverse transcriptase. Retroviruses open host cell DNA and graft in their retroviral RNA, integrating into the host genome. The immune system has difficulty recognizing or ridding of foreign DNA that has become its own. Discovering Retroviruses presents the history of retrovirus discovery. Skalka illuminates retroviruses' role in evolution, human health, and disease, from the first sighting at the end of the nineteenth century to recent use in genetic engineering. Retroviral sequences in the human genome mark sites where endogenous retrovirus integrated over six million years ago. The 100,000 pieces of retrovirus DNA are remnants from germ line cell invasions and total approximately eight percent of the human genome. Through investigation of animal and human retroviral sequences, we know retroviral mutations can lead to cancers and immunodeficiencies, including HIV and leukemia. Today, researchers harness retroviruses for use in gene delivery systems and precision medicine advances. Discovering Retroviruses offers a lively perspective on stories of the major pioneers of the past century and the extraordinary roads to their discoveries, and demonstrates the growing importance of genetics to modern biomedicine.-- Provided by publisher
Book
Risks and features of secondary infections in severe and critical ill COVID-19 patients
Objectives Severe or critical COVID-19 is associated with intensive care unit admission, increased secondary infection rate, and would lead to significant worsened prognosis. Risks and characteristics relating to secondary infections in severe COVID-19 have not been described. Methods Severe and critical COVID-19 patients from Shanghai were included. We collected lower respiratory, urine, catheters, and blood samples according to clinical necessity and culture and mNGS were performed. Clinical and laboratory data were archived. Results We found 57.89% (22/38) patients developed secondary infections. The patient receiving invasive mechanical ventilation or in critical state has a higher chance of secondary infections (P<0.0001). The most common infections were respiratory, blood-stream and urinary infections, and in respiratory infections, the most detected pathogens were gram-negative bacteria (26, 50.00%), following by gram-positive bacteria (14, 26.92%), virus (6, 11.54%), fungi (4, 7.69%), and others (2, 3.85%). Respiratory Infection rate post high flow, tracheal intubation, and tracheotomy were 12.90% (4/31), 30.43% (7/23), and 92.31% (12/13) respectively. Secondary infections would lead to lower discharge rate and higher mortality rate. Conclusion Our study originally illustrated secondary infection proportion in severe and critical COVID-19 patients. Culture accompanied with metagenomics sequencing increased pathogen diagnostic rate. Secondary infections risks increased after receiving invasive respiratory ventilations and intravascular devices, and would lead to a lower discharge rate and a higher mortality rate.
Journal Article
COVID-19 : the pandemic that never should have happened, and how to stop the next one
Over the last 30 years, we learned every lesson needed to stop this coronavirus outbreak in its tracks. We heeded almost none of them. The result is a pandemic on a scale never before seen in our lifetimes. Here, science journalist Debora MacKenzie lays out the full story of how and why it happened: the previous viruses that should have prepared us, the shocking public health failures that paved the way, the failure to contain the outbreak, and most importantly, what we must do to stop this happening again. Offering a compelling history of the most significant recent outbreaks, including SARS, MERS, H1N1, Zika, and Ebola, MacKenzie outlines the lessons we failed to learn from each past crisis. But looking forward, she makes a bold, optimistic argument : this pandemic might finally galvanize the world to take viruses seriously. No one has yet brought together our knowledge of Covid-19 in a comprehensive, informative, and accessible way. But that story can already be told, and Debora MacKenzie's urgent telling is required reading for these times and beyond. Fighting this pandemic and preventing the next one will take political action of all kinds, globally, from governments, the scientific community, and individuals -- and if we act now, it is possible.
Book
Staphylococcus aureus Screening and Decolonization in Orthopaedic Surgery and Reduction of Surgical Site Infections
Background
Staphylococcus aureus is the most common organism responsible for orthopaedic surgical site infections (SSIs). Patients who are carriers for methicillin-sensitive S. aureus or methicillin-resistant S. aureus (MRSA) have a higher likelihood of having invasive S. aureus infections. Although some have advocated screening for S. aureus and decolonizing it is unclear whether these efforts reduce SSIs.
Questions/purposes
The purposes of this study were to determine (1) whether S. aureus screening and decolonization reduce SSIs in orthopaedic patients and (2) if implementing this protocol is cost-effective.
Methods
Studies for this systematic review were identified by searching PubMed, which includes MEDLINE (1946–present), EMBASE.com (1974–present), and the Cochrane Library’s (John Wiley & Sons) Cochrane Database of Systematic Reviews (CDSR), Cochrane Central Register of Controlled Trials (CENTRAL), Database of Abstracts of Reviews of Effects (DARE), Health Technology Assessment Database (HTAD), and the NHS Economic Evaluation Database (NHSEED). Comprehensive literature searches were developed using EMTREE, MeSH, and keywords for each of the search concepts of decolonization, MRSA, and orthopedics/orthopedic surgery. Studies published before 1968 were excluded. We analyzed 19 studies examining the ability of the decolonization protocol to reduce SSIs and 10 studies detailing the cost-effectiveness of S. aureus screening and decolonization.
Results
All 19 studies showed a reduction in SSIs or wound complications by instituting a S. aureus screening and decolonization protocol in elective orthopaedic (total joints, spine, and sports) and trauma patients. The S. aureus screening and decolonization protocol also saved costs in orthopaedic patients when comparing the costs of screening and decolonization with the reduction of SSIs.
Conclusions
Preoperative screening and decolonization of S. aureus in orthopaedic patients is a cost-effective means to reduce SSIs.
Level of Evidence
Level IV, systematic review of Level I–IV studies. See the Guidelines for Authors for a complete description of levels of evidence.
Journal Article