Explore the vast range of titles available.

Lemon balm and corn silk are valuable medicinal herbs, which exhibit variety of beneficial effects for human health. The present study explored the anti-obesity effects of a mixture of lemon balm and corn silk extracts (M-LB/CS) by comparison with the effects of single herbal extracts in high-fat diet (HFD)-induced obesity in mice. HFD supplementation for 84 days increased the body weight, the fat mass density, the mean diameter of adipocytes, and the thickness of fat pads. However, oral administration of M-LB/CS significantly alleviated the HFD-mediated weight gain and adipocyte hypertrophy without affecting food consumption. Of the various combination ratios of M-LB/CS tested, the magnitude of the decreases in weight gain and adipocyte hypertrophy by administration of 1:1, 1:2, 2:1, and 4:1 (w/w) M-LB/CS was more potent than that by single herbal extracts alone. In addition, M-LB/CS reduced the HFD-mediated increases in serum cholesterol, triglyceride, and low-density lipoprotein, prevented the reduction in serum high-density lipoprotein, and facilitated fecal excretion of cholesterol and triglyceride. Moreover, M-LB/CS mitigated the abnormal changes in specific mRNAs associated with lipogenesis and lipolysis in the adipose tissue. Furthermore, M-LB/CS reduced lipid peroxidation by inhibiting the HFD-mediated reduction in glutathione, catalase, and superoxide dismutase. Therefore, M-LB/CS is a promising herbal mixture for preventing obesity.

We recently reported that varying combination ratios of lemon balm (Mellissa officinalis L.) and corn silk extracts (Stigma of Zea mays L. fruit) could reduce the obesity caused by a high-fat diet (HFD). The present study investigated the dose-dependent effect of a 1:1 (w:w) mixture of lemon balm and corn silk extracts (M-LB/CS) on HFD-mediated metabolic disorders and compared the effect with metformin. Oral administration of 50–200 mg/kg of M-LB/CS for 84 days significantly inhibited HFD-induced body weight gain, adipocyte hypertrophy, and lipogenic gene induction without affecting food consumption in mice. Biochemical analyses showed that M-LB/CS blocked abnormal lipid accumulation in the blood by escalating fecal lipid excretion. In addition, M-LB/CS prevented HFD-mediated pancreatic atrophy, decreased the number of insulin- and glucagon-immunoreactive cells, and inhibited increases in glycated hemoglobin, glucose, and insulin. Moreover, M-LB/CS also reduced hepatic injury, lipid accumulation, gluconeogenesis, and lipid peroxidation in parallel with the induction of AMP-activated protein kinase and antioxidant enzymes. Furthermore, M-LB/CS protected the kidney by inhibiting tubular vacuolation and reducing serum creatinine and blood urea nitrogen levels. The prophylactic effect of 100 mg/kg M-LB/CS-administration was comparable to that of metformin. Therefore, M-LB/CS may be an alternative option for managing obesity and its related metabolic disorders.

Open singles: Z Stanbury, r-up P Parker. Intermedate singles: M Loach. Junior singles: M Lemon, r-up L Johnston. Champ fours: K Smith, D Hyland, M Loach, L Johnston, r-up Z Stanbury, E Dennison, I Percival, J Green. Champion triples: M Wakefield, A Pooke, M Hannan, r-up R Burke, B Forbes, I Percival. Champion pairs: Z Stanbury, P Parker, r-up M Barris, M Lemon. Club fours: M Munro, M Coonery, V Collie, O Welford. Club triples: I Pooke, I Percival, M A Taylor. Handicap pairs: R Burke, J Giles. Handicap singles: P Parker. Gold button pairs: M Taylor, M Lemon. Pat Small Trophy: I Dixon, M Lemon. Stanbury Trophy (2x4x2 pairs): Z Stanbury, O Welford. Margaret Seaton Trophy (most improved u-10): L Johnston. Arnst Trophy: West End. Dulcie McConnel Trophy: Geraldine. Squad:-Hannah Broederlow (Palmerston North Girls High School) GD, GK, WD; Lauren Burgess (Inglewood High School) WD, GD; Keisha Grant (New Plymouth Girls High School) C, WA; Jamilah Gupwell (New Plymouth Girls High School) GA, GS; Everlyn Horomia (Hillcrest High School) WA, C; Catherine Latu (Massey High School) GS, GK; Sharlene Lowe(Nelson Girls High School) WA, GA; Elizabeth Manu (Rangi Ruru) GD, WD, GK; Finau Pulu (Auckland Girls Grammar) GD, GK, WD; Te Huinga Reo Selby-Rickit (Te Kura Kaupapa Maori o Te Rito) GK, GD; Jessica Tuki (Sacred Heart New Plymouth) GS, GA; Maria Tutaia (Mt Albert Grammar School) GS, GA.

Wesley G. and Virginia M. Lemon, Akron, celebrated their 60th wedding anniversary at a family celebration held Saturday, Aug. 9, at St. Paul's Evangelical Congregational Church, Reamstown.

Survivors: Sons, Thomas W. of Center Valley and Robert P. of Severn, Md.; daughters, Joyce Delstine of Yuba City, Calif., and Debi Heller of Longwood, Fla.; sisters, Margaret Schafer, Evelyn Kennedy and Mildred Williamson, all of Hickory, Washington County; 11 grandchildren and three great-grandchildren...

The book Philosophy of History: A Guide for Students, written by M. C. Lemon, is reviewed.

Harley R. Johnson DOVER Harley R. Johnson, 29, died Tuesday, May 29, 2007. He was the son of Fred L. and Claudette D. (Lemon) Seiler of Dover. A celebration in remembrance of Harley's life will be from 2 to 8 p.m. today at his parents' home at 3045 Spectrum Drive, Dover.

Larry S. and D. Lynette Cagle, of Marion, Ill., announce the engagement of their daughter Lisa L. to Joseph M.

Il est l'ancien secrétaire parlementaire de [Stephen Harper], ex-porte-parole des conservateurs sur les questions éthiques. Chaînes aux poignets et aux chevilles. La chute de [Dean Del Mastro] est brutale. L'affaire remonte à 2008, l'avant-dernière campagne électorale. Dean Del Mastro, qui était déjà député, a alors dépassé la limite des dépenses permises et soumis sciemment un document falsifié à Élections Canada. La juge, qui lui impose un mois de prison, soutient qu'il a menti et triché. Elle qualifie ses gestes d'affront à la démocratie. Pour la Couronne, une peine d'emprisonnement était nécessaire.

The eight-member commission, which is appointed by the governor, sets policy for HRSD, the regional utility that provides wastewater treatment services for more than 1.5 million people in 17 cities and counties. Gloucester, King William, Mathews and Middlesex are among the counties served by HRSD.