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Accurate estimation of forest aboveground biomass (AGB) and understanding its ecological drivers are vital for carbon monitoring and sustainable forest management. However, AGB estimation using remote sensing is hindered by signal saturation in high-biomass areas and insufficient attention to ecological structural factors. Focusing on Guangdong Province, this study proposes a novel approach that spatially extrapolates airborne LiDAR-derived Forest structural parameters and integrates them with Sentinel-1/2 data to construct an AGB prediction model. Results show that incorporating structural parameters significantly reduces saturation effects, improving prediction accuracy and AGB maximum range in high-AGB regions (R2 from 0.724 to 0.811; RMSE = 10.64 Mg/ha; max AGB > 180 Mg/ha). Using multi-scale geographically weighted regression (MGWR), we further examined the spatial influence of forest type, age structure, and species mixture. Forest age showed a strong positive correlation with AGB in over 95% of the area, particularly in mountainous and hilly regions (coefficients up to 1.23). Species mixture had positive effects in 87.7% of the region, especially in the north and parts of the south. Natural forests consistently exhibited higher AGB than plantations, with differences amplifying at later successional stages. Highly mixed natural forests showed faster biomass accumulation and higher steady-state AGB, highlighting the regulatory role of structural complexity and successional maturity. This study not only mitigates remote sensing saturation issues but also deepens understanding of spatial and ecological drivers of AGB, offering theoretical and technical support for targeted carbon stock assessment and forest management strategies.

In recent years, a growing body of research has investigated the factors influencing land surface temperature (LST) in different cities, employing diverse methodologies. Our study aims to be one of the few to examine the socio-environmental variables (SV) of LST with a holistic approach, especially in primate cities in developing countries, which are particularly vulnerable to the impacts of climate change. In this context, the study preliminarily identifies the SV of LST while investigating the most vulnerable areas related to extreme LST at the neighborhood level. The combined 11 variables are analyzed using spatial modeling methods (GWR and MGWR). The MGWR model outperforms the GWR model with an adjusted R2 of 0.96. The results showed that: (1) the 65+ population is negatively associated with LST in 95% of neighborhoods; the socioeconomic index–LST relationship is negative in 65% of neighborhoods. (2) In 90% of the neighborhoods where the relationship between LST and the built environment ratio is positive, the socioeconomic level decreases while household size increases in 98% of the neighborhoods. (3) In 62% of the neighborhoods where the relationship between the 65+ population and LST is negative, the relationship between the socioeconomic level and LST is negative. This study aids decision-makers and planners in managing urban resources to reduce extreme LST exposure region by region and recommending multiscale policies to control determinant influences on LST.

To provide data that can guide community-targeted practices, policies, and interventions in urban metropolitan areas, we used geospatial analysis to examine the community-level opioid overdose death determinants and their spatial variation across a study area. We obtained spatial datasets containing multiple, high-quality measures of socioeconomic conditions, public health status, and demographics for analysis and visualization in geographic information systems. We employed a multiscale modeling approach (multiscale geographically weighted regression; MGWR) to provide a comprehensive and robust analysis of opioid overdose death determinants, explain how geospatial patterns vary across scales across Milwaukee County in 2019, and examine the differential influence of factors locally, regionally, and globally. We subsequently examined how associations varied with the racial/ethnic composition of communities by dividing Milwaukee County into White-majority, Black-majority, and Hispanic-majority regions according to census data and conducting separate, independent modeling processes. Overall, the multiscale model explained 83% of opioid overdose death variability across neighborhoods in Milwaukee County using 12 selected variables. Statistical analysis and geovisualization of patterns, trends, and clusters using MGWR unveiled dramatic racialized health disparities in Milwaukee, showing how factors that influenced opioid overdose deaths varied across diverse communities in Milwaukee. The observed geographic variation in relationships included the impact of naloxone availability and incarceration rates on overdose deaths with pronounced differences between White communities and communities of color. Understanding, community-level factors that contribute to overdose risk should guide targeted community-level solutions. Overall, our findings demonstrate the value of precision epidemiology using MGWR analysis for defining and guiding responses to public health challenges.

The concept of ‘spatial scale’, or simply ‘scale’ is implicit in any discussion of global versus local models. The raison d’etre of local models is that a global scale (where here ‘global’ simply refers to all locations within a predefined area of interest) might be the incorrect scale at which to undertake any analysis of spatial processes; the alternative being a local scale (where here ‘local’ refers to individual locations). Here we explore two well-known scale issues in the context of local modeling: the modifiable areal unit problem (MAUP) and Simpson’s paradox. In doing so, we highlight that scale effects play two very different roles in any consideration of local versus global modeling. First, we examine the sensitivity of global and local models to the MAUP and show how the effects of the MAUP in global models are a function of the degree to which processes vary over space. This generates a new insight into the MAUP: it results from the properties of processes rather than the properties of data. Then we highlight the extreme differences that can result when calibrating global and local models and how Simpson’s paradox can arise in this context. In the examination of the MAUP, scale is treated as a measure of the degree to which data are aggregated prior to any form of modeling; in the study of Simpson’s paradox, scale refers to the geographical entity for which a model is calibrated.

Background Pneumonia remains a major cause of morbidity and mortality, particularly in low- and middle-income countries, such as Pakistan. In this study, we aimed to examine the spatial and temporal patterns of pneumonia incidence in South Punjab, Pakistan, and to analyze their association with socio-ecological factors. Methods We used case report data from the district health information system (DHIS) over the years 2016 to 2020 and applied global and local Moran’s I to identify spatial autocorrelation. Furthermore, we employed hot and cold spot analysis to identify significant areas with high and low pneumonia incidence. We used Emerging Hot Spot Analysis (EHSA) and time series clustering to examine shifting and temporal patterns of incidence, respectively. In addition, Generalized Linear Regression (GLR) and Multiscale Geographically Weighted Regression (MGWR) models were used to analyze geographic variation in the association of socio-ecological factors and pneumonia incidence. Results Our results showed no significant global clustering of pneumonia incidence. Local Moran’s I identified a low-low cluster in DG Khan, while Hot Spot Analysis detected one hot spot in Rajanpur. Multan City showed higher case counts, but this reflected population concentration rather than elevated incidence rates. The temporal analysis confirmed a significant seasonal variation, as well as a decrease in certain Tehsils and an increase in others. Our MGWR model revealed that better female literacy reduced incidence rates of pneumonia, whereas poor housing quality increased incidence rates of pneumonia, particularly in the southwestern areas of South Punjab. Conclusions We conclude that socio-ecological variables significantly influenced the incidence of pneumonia in South Punjab, and this association varies substantially over time and space. Our results emphasize the need for locally specific public health interventions to minimize pneumonia incidence in vulnerable populations in Pakistan. Our spatial epidemiological approach can be adapted to other regions of Pakistan and similar socio-ecological contexts in low- and middle-income countries.

The rise in “urban diseases” like population density, traffic congestion, and environmental pollution has renewed attention to urban livability. Walkability, a critical measure of pedestrian friendliness, has gained prominence in urban and transportation planning. This research delves into a comprehensive analysis of walking accessibility, examining both subjective and objective aspects. This study aims to identify the influencing factors and explore the underlying mechanisms driving walkability within a specific area. Through a questionnaire survey, residents’ subjective perceptions were gathered concerning various factors such as traffic operations, walking facilities, and the living environment. Structural equation modeling was employed to analyze the collected data, revealing that travel experience significantly impacts perceived accessibility, followed by facility condition, traffic condition, and safety perception. In the objective analysis, various types of POI data served as explanatory variables, dividing the study area into grids using ArcGIS, with the Walk Score® as the dependent variable. Comparisons of OLS, GWR and MGWR demonstrated that MGWR yielded the most accurate fitting results. Mixed land use, shopping, hotels, residential, government, financial, and medical public services exhibited positive correlations with local walkability, while corporate enterprises and street greening showed negative correlations. These findings were attributed to the level of development, regional functions, population distribution, and supporting facility deployment, collectively influencing the walking accessibility of the area. In conclusion, this research presents crucial insights into enhancing walkability, with implications for urban planning and management, thereby enriching residents’ walking travel experience and promoting sustainable transportation practices. Finally, the limitations of the thesis are discussed.

After mosquitoes, ticks are the most important vectors of infectious diseases. They play an important role in public health. In recent decades, we discovered new tick-borne diseases; additionally, those that are already known are spreading to new areas because of climate change. Slovenia is an endemic region for Lyme borreliosis and one of the countries with the highest incidence of this disease on a global scale. Thus, the spatial pattern of Slovenian Lyme borreliosis prevalence was modelled with 246 indicators and transformed into 24 uncorrelated predictor variables that were applied in geographically weighted regression and regression tree algorithms. The projected potential shifts in Lyme borreliosis foci by 2050 and 2070 were calculated according to the RCP8.5 climate scenario. These results were further applied to developing a Slovenian Lyme borreliosis infection risk map, which could be used as a preventive decision support system.

Biodiversity maintenance function (BMF) denotes the capacity of ecosystems to sustain genetic, species, ecosystem, and landscape diversity. Assessing the spatial distribution and underlying drivers of BMF at the regional scale is essential for biodiversity management. However, research on the socio-ecological drivers of BMF from a geographical perspective remains scarce. Therefore, this study developed an integrated assessment framework encompassing climatic factors, species richness, vegetation status, ecosystem protection, and anthropogenic disturbance. We analyzed the BMF spatial patterns across Liaoning Province, China, and identified the dominant drivers and their spatial heterogeneity using multi-scale geographically weighted regression and geographical detector. The results show that (1) the eastern/western mountainous regions and Liaohe River estuary are critical BMF zones for prioritized conservation; (2) BMF spatial variation is mainly shaped by precipitation, temperature, slope, and forestland/farmland proportion, with factor interactions amplifying their impacts; (3) drivers show distinct spatial heterogeneity. Specifically, precipitation, slope, and NDVI exert homogeneous effects, whereas elevation, temperature, farmland/wetland proportion, and GDP exhibit pronounced heterogeneity. Natural factors generally exert positive effects, while the farmland/urban proportion tends to exert negative impacts—for example, farmland’s negative influence is stronger in the west, whereas the forestland and temperature exert more positive effects in the east. The results enhance the methodological framework for elucidating the spatial relationships between BMF and drivers, providing a scientific basis for biodiversity conservation and ecosystem management in Liaoning Province and similar regions.