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Introduction Enthusiasm for manicures is at a high amongst young populations and has led to a growth in nail cosmetology in the last decade. Reviewing the known nail and cutaneous adverse outcomes associated with manicures can improve counseling for safe usage. Aims To provide a comprehensive review of cutaneous disorders reported with various types of nail cosmetics, to allow consumers to make informed decisions when choosing a manicure type. In addition, this article promotes cognizance amongst dermatologists of potential causes of dermatologic conditions associated with nail cosmetics. Methods A literature review of articles from January 2014 to December 2025 was conducted on the PubMed database. A combination including, but not limited to, the following terms was utilized: nails, cosmetics, nail disease, adverse outcomes, or pedicure. Results The most common reported adverse outcomes of gel manicures include psoriasiform onychodystrophy, pterygium inversum unguis (PIU), allergic contact dermatitis (ACD), onycholysis, paronychia, pseudo‐psoriatic nails, and onychomycosis. The most commonly reported adverse outcomes of acrylic manicures include worn‐down nail syndrome, pseudo‐psoriatic nails, ACD, onychomycosis, onycholysis, periungual eczema, and pseudo‐psoriatic allergic nail dystrophy. Risk factors for adverse outcomes include using ultraviolet (UV) light, at‐home manicures, acrylates, and isocyanates. Conclusion With the increased popularity of manicures, awareness of adverse outcomes associated with manicure types can improve counseling and management. Inclusion of allergens in the baseline allergy patch testing series and caution for photo‐protection in at‐risk populations should be encouraged.

Background About 90% of women worldwide use nail care products, including manicure ones. A manicure procedure results in nail damage, therefore it is necessary to search for new, objective methods of assessing the impact of the procedures and products applied within the nail plate. In this study, an attempt was made to quantify the impact of manicure procedures on the nail plate condition. Materials and methods Twenty thumb nail plates were examined. Before the manicure procedures, alginate casts were prepared for each of the subjects. The analysis of the three‐dimensional (3D) nail surface structure included the assessment of the nail sections and the assessment of differences in the nail structure after superposition of 3D images of the nail plates before and after the manicure procedures. Results The obtained results show that the nail plate structure changed to a similar extent in each measured section after the manicure procedure. A change in the height of the nails is not a desirable phenomenon as it suggests damage to the nail caused by the substances included in the preparations applied to the nails, acetone, or filing the nail plate. This proves the great influence of the technique of removing artificial nails on the structure of the natural plate. Conclusion The use of a 3D scanner allows for precise, biometric, quantitative, and repeatable measurements of changes in the nail structure after a manicure procedure. The use of the hybrid and gel manicure procedure causes significant damage to the nail plate, especially in its distal portion.

The main purpose of this work was to determine if the use of hybrid nail polishes causes changes in concentration of the most important sulfur amino acids that build nail plate structures, cysteine and methionine. We found that the average contents of cysteine and methionine in studied samples before the use of hybrid manicure were 1275.3 ± 145.9 nmol mg−1 and 111.7 ± 23.8 nmol mg−1, respectively. After six months of hybrid manicure use, the average amount of these sulfur amino acids in studied samples were 22.1% and 36.5% lower in the case of cysteine and methionine, respectively. The average amounts of cysteine and methionine in nail plate samples after the use of hybrid manicures were 992.4 ± 96.2 nmol mg−1 and 70.9 ± 14.8 nmol mg−1, respectively. We also confirmed that in studied women the application of UV light varnishes reduced the thickness of the nail plate, from 0.50 ± 0.12 mm before to 0.46 ± 0.12 mm after the use of the hybrid manicure.

‘Manicure Finger’ grape exhibits gradient coloration during veraison, where the lower part of the skin changes color faster and intenser than the upper, giving the same berry a gradient color from green on the top to red on the bottom. This unique characteristic distinguishes it from other table grape varieties and makes it highly commercially valuable. However, because the formation mechanisms of gradient coloration are unclear, ‘Manicure Finger’ lags behind other grapes in the development of breeding, cultivation, and storage technologies, occupying only a small share of the table grape market. Here, based on integrated omics including anthocyanin, flavonoid metabolome, and transcriptome, the substances basis and metabolic mechanisms regulating gradient coloration were thoroughly resolved. In ‘Manicure Finger’, eight anthocyanins including malvidin‐3‐O‐glucoside, peonidin‐3‐O‐glucoside, and cyanidin‐3‐O‐glucoside were identified as color‐presenting substances, while flavones and flavonols, especially kaempferol‐3‐O‐rutinoside and quercetin‐3‐O‐glucoside, functioned as co‐pigments. Spatial differences in their accumulation were substances basis for gradient coloration. In the lower skin, these substances accumulated faster due to the higher expression levels of structural genes VvF3´5´H1, VvF3´5´H2, VvANS, VvGT1, and VvFAOMT, which were further modulated by transcription factors VvMYBA1, VvMYBA2, VvMYBA3, and VvMYBA6. Novel transcription factors VvbHLH148, VvMYBA22, and VvMYBA3 were also most probably involved in this regulatory process. Histone acylation regulated by VvHAC1 and lysine methylation regulated by VvHMT1 might underlie the epigenetic basis of gradient coloration. Overall, the metabolic networks underlying gradient coloration were comprehensively constructed at levels of color‐presenting substances, structural genes and transcription factors, offering valuable insights into the precise regulation of ‘Manicure Finger’ color formation. Based on integrated omics, the metabolic regulation networks underlying gradient coloration of ‘Manicure Finger’ grape were constructed at three levels of color‐presenting substances, structural genes, and transcription factors.

Introduction Acrylates are widespread plastic materials, known for their sensitizing properties. So far, allergy to acrylate monomers has been known as occupational eczema, mainly concerning dentists and manicurists. However, a surge of allergic contact dermatitis (ACD) cases related to acrylates among users of hybrid varnishes have recently been reported. Aim: This article reviews the pathogenesis, clinical manifestations, and dermoscopic features of contact eczema induced by hybrid manicure. Material and methods The study was performed on a group of 8 women. Clinical and dermoscopic features were evaluated and correlated with the period of exposure to acrylates. In addition, all patients underwent mycological examination to exclude fungal co-infection. Results Mycological examinations in all patients gave negative results, although 1 patient developed local secondary mixed supra-infection due to Pseudomonas aeruginosa and Candida spp. Distribution of clinical manifestations corresponded to the area of contact with the allergen and comprised both skin and nail changes. The severity of inflammation correlated positively with the exposure period. Subungual hyperkeratosis and onycholysis were the most common findings (8/8 patients), and eczematous finger pulp fissuring was a rarer sign (2/8 patients) but more specific clinically. Conclusions The surge of contact dermatitis related to acrylates seen in recent years requires dermatologists’ awareness. Nail changes induced by hybrid manicure can mimic onychomycosis or nail psoriasis. Therefore comprehensive patch testing should be performed in doubtful cases. Due to the lack of patch tests in our study, we can only suspect that we were dealing with allergic contact dermatitis. In case of confirmed allergy to acrylates, the patient should be aware of this and avoid them.

Beauty salons make a considerable part of the service sector. However, although the beauty salon staffs are exposed to a vast number of ambient chemicals during the whole workday, the occupational health hazard and the indoor air quality in beauty salons are poorly known. Specifically, reports on relations between indoor particulate matter and its outdoor or indoor sources in beauty salons are rare. Here we studied the effects of external and internal sources of aerosol in beauty salons on indoor ambient particulate matter and on its elemental and organic carbon contents. We selected four beauty salons differing in the number and type of particulate matter indoor and outdoor sources. The approach consisted in taking ten eight-hour samples of total suspended particulate matter and ten samples of its respirable sub-fraction simultaneously indoors and outdoors at each site, then analyzing them for carbon content using a thermo-optical method. The ambient concentrations of particulate matter and organic carbon were higher indoors than outdoors. We show that differences between indoor and the outdoor concentrations is due to the indoor use of cosmetics and other human activity. The effects of indoor sources on indoor elemental carbon concentrations are lower than on organic carbon concentrations.

Background: Since manicure and pedicure professionals are exposed to blood and to other human body fluids, these workers are susceptibile to hepatitis viruses (HBV, HCV) when they fail to follow standard safety procedures (SSP) in their work routine. Knowledge on SSP is one of the main factors to reduce contamination risks. Objectives: The current study investigated correlations between knowledge on SSP and the occurrence of HBV/HCV in manicure/pedicure professionals working at beauty salons in Maringá (Paraná-Brazil). Methods: A cross-sectional study was conducted between March 2015 and March 2016. Beauty salons (n = 30) were visited and 150 professionals completed a questionnaire and a rapid test for HBV/HCV detection. Results: Data indicated that there were no correlations (P < 0.01) between knowledge about transmission and prevention of viral hepatitis and professional behaviors of manicure/pedicure in beauty salons of Maringá. There was low adherence (P < 0.01) to SSP and to procedures that would guarantee an adequate sterilization of the materials used. One out of 150 individuals showed reactivity for HBV (genotype D by HBV DNA). Conclusions: Manicure and pedicure professionals in Maringá were aware of the correct procedures to warrant personal protection, yet such knowledge is not adequately applied in their work routine.

The nail as an anatomic structure protects the terminal phalanx of the digit from injury. Historically, it has served as a tool for protection and for survival. As civilizations developed, it attained the additional function of adornment. Nail beautification is a big industry today, with various nail cosmetics available, ranging from nail hardeners, polishes, extensions, artificial/sculpted nails, and nail decorations. Adverse events may occur either during the nail-grooming procedure or as a reaction to the individual components of the nail cosmetics. This holds true for both the client and the nail technician. Typically, any of the procedures involves several steps and a series of products. Separate \"nail-bars\" have been set up dedicated to serve women and men interested in nail beautification. This article attempts to comprehensively inform and educate the dermatologist on the services offered, the products used, and the possible/potential adverse effects related to nail-grooming and nail cosmetics.

Two women, virtual strangers, sit hand-in-hand across a narrow table, both intent on the same thing-achieving the perfect manicure. Encounters like this occur thousands of times across the United States in nail salons increasingly owned and operated by Asian immigrants. This study looks closely for the first time at these intimate encounters, focusing on New York City, where such nail salons have become ubiquitous. Drawing from rich and compelling interviews, Miliann Kang takes us inside the nail industry, asking such questions as: Why have nail salons become so popular? Why do so many Asian women, and Korean women in particular, provide these services? Kang discovers multiple motivations for the manicure-from the pampering of white middle class women to the artistic self-expression of working class African American women to the mass consumption of body-related services. Contrary to notions of beauty service establishments as spaces for building community among women, The Managed Hand finds that while tentative and fragile solidarities can emerge across the manicure table, they generally give way to even more powerful divisions of race, class, and immigration.