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This book examines genealogies of contagion in between contagion as microbe and contagion as affect. It analyzes how and why hygiene became authoritative and succeeded in becoming a part of the broader social and cultural vocabulary within the colonialist, anti-colonial, as well as modernist discourses.

Background In the absence of definitive diagnosis, healthcare providers are likely to prescribe empirical antibacterials to those who test negative for malaria. This problem is of critical importance in Southern Asia (SA) and South-eastern Asia (SEA) where high levels of antimicrobial consumption and high prevalence of antimicrobial resistance have been reported. To improve management and guide further diagnostic test development, better understanding is needed of the true causative agents of fever and their geographical variability. Methods We conducted a systematic review of published literature (1980–2015) to characterise the spectrum of pathogens causing non-malarial febrile illness in SA and SEA. We searched six databases in English and French languages: MEDLINE, EMBASE, Global Health (CABI) database, WHO Global Health Library, PASCAL, and Bulletin de la Société Française de Parasitologie (BDSP). Selection criteria included reporting on an infection or infections with a confirmed diagnosis, defined as pathogens detected in or cultured from samples from normally sterile sites, or serological evidence of current or past infection. Results A total of 29,558 records from 19 countries in SA and SEA were screened, of which 2410 (8.1%) met the selection criteria. Bacterial aetiologies were reported in 1235 (51.2%) articles, viral in 846 (35.1%), parasitic in 132 (5.5%), and fungal in 54 (2.2%), and 143 (6.0%) articles reported more than one pathogen group. In descending order of frequency, Salmonella Typhi, Escherichia coli , Staphylococcus aureus , Klebsiella pneumoniae , and coagulase negative Staphylococcus were the commonly reported bacteria, while dengue virus, chikungunya virus, Japanese encephalitis virus, hepatitis B virus, and hepatitis C virus were common viral pathogens reported. Reports of rarely reported or emerging pathogens included a case report of Borrelia burgdorferi (Lyme disease) in India in 2010 and reports of Nipah virus in Singapore and India. Conclusions This review summarises the reported non-malaria pathogens that may cause febrile illness in SA and SEA. The findings emphasise the need of standardising the reporting of aetiological studies to develop effective, evidence-based fever management and improved surveillance. Research and development of diagnostic tools would benefit from up-to-date epidemiological reporting of the regional diversities of non-malaria fever aetiologies. Trial registration PROSPERO registration, CRD42016049281

Land surface phenology is widely retrieved from satellite observations at regional and global scales, and its long-term record has been demonstrated to be a valuable tool for reconstructing past climate variations, monitoring the dynamics of terrestrial ecosystems in response to climate impacts, and predicting biological responses to future climate scenarios. This study detected global land surface phenology from the advanced very high resolution radiometer (AVHRR) and the Moderate Resolution Imaging Spectroradiometer (MODIS) data from 1982 to 2010. Based on daily enhanced vegetation index at a spatial resolution of 0.05 degrees, we simulated the seasonal vegetative trajectory for each individual pixel using piecewise logistic models, which was then used to detect the onset of greenness increase (OGI) and the length of vegetation growing season (GSL). Further, both overall interannual variations and pixel-based trends were examined across Koeppen’s climate regions for the periods of 1982–1999 and 2000–2010, respectively. The results show that OGI and GSL varied considerably during 1982–2010 across the globe. Generally, the interannual variation could be more than a month in precipitation-controlled tropical and dry climates while it was mainly less than 15 days in temperature-controlled temperate, cold, and polar climates. OGI, overall, shifted early, and GSL was prolonged from 1982 to 2010 in most climate regions in North America and Asia while the consistently significant trends only occurred in cold climate and polar climate in North America. The overall trends in Europe were generally insignificant. Over South America, late OGI was consistent (particularly from 1982 to 1999) while either positive or negative GSL trends in a climate region were mostly reversed between the periods of 1982–1999 and 2000–2010. In the Northern Hemisphere of Africa, OGI trends were mostly insignificant, but prolonged GSL was evident over individual climate regions during the last 3 decades. OGI mainly showed late trends in the Southern Hemisphere of Africa while GSL was reversed from reduced GSL trends (1982–1999) to prolonged trends (2000–2010). In Australia, GSL exhibited considerable interannual variation, but the consistent trend lacked presence in most regions. Finally, the proportion of pixels with significant trends was less than 1 % in most of climate regions although it could be as large as 10 %.

At present India is a leading producer, distributor, and consumer of generic medicines globally. Disparate Remedies traces the genealogy of this development and examines the public cultures of medicine in the country between 1870 and 1960. The book begins by discussing the expansion of medical consumerism in late nineteenth-century India when British-owned firms extended their sales into remote towns. As a result, laboratory-produced drugs competed with traditional remedies through side-by-side production of Western and Indian drugs by pharmaceutical companies. The emergent middle classes, the creation of a public sphere, and nationalist politics transformed the medical culture of modern India and generated conflict between Western and Indigenous medical systems and their practitioners. Nandini Bhattacharya demonstrates that these disparate therapies were sustained through the tropes of purity or adulteration, potency or lack of it, and epistemic heritage, even when their material configuration often differed little. Uniquely engaging with the cultures of both consumption and production in the country, Disparate Remedies follows the evolution of medicine in colonial India as it confronted Indian modernity and changing public attitudes surrounding health and drugs.

Using case studies of cholera, plague, malaria, and yellow fever, this book analyzes how factors such as public health diplomacy, trade, imperial governance, medical technologies, and cultural norms operated within global and colonial conceptions of political and epidemiological risk to shape infectious disease policies in colonial India.

In the mid-1800s, plantation-produced tea from India came onto the British market. Tea retailers blended this more malty and black tea with the lighter Chinese-grown tea to which consumers had become accustomed. By the turn of the 20th century, blending helped Empire-grown tea supplant Chinese-grown tea on the market. Scholars of tea have shown how British tea companies working in South Asia stoked racialized fears that Chinese tea arrived in Britain in an adulterated state, laden with impurities that included dyes, perfumes and even human sweat. This article describes how concerns about protecting tea leaves from outside adulteration gave way to concerns about the potential digestive threat that lay inside tea leaves themselves. Medical journals linked the increased consumption of Indian teas to a population-wide ‘epidemic’ of indigestion. The most cited culprits in this epidemic were tannins, chemical compounds that were also thought to give black tea its characteristic bitterness and color. The normalization of black tea consumption among the British public was not just a work of marketing or branding but a work of resolving uncertainty about what tannins were at a material, biophysical level. As this uncertainty was resolved scientifically, tea was materialized not as a singular, unified product but as an active chemical assemblage.

Chikungunya (CHIK), a mosquito borne debilitating disease, is caused by CHIK virus, an alphavirus belonging to the family Togaviridae. The sudden onset of very high fever along with rash, and severe arthralgia especially in the small joints of hands and toes are the characteristics of the disease. It was first reported from Tanzania in 1952–53 and spread subsequently to sub-Saharan Africa, South East Asia and Pacific causing large epidemics. The virus exists in three genotypes, the Asian, West African and East Central South African that are responsible for outbreaks in the respective areas. The first outbreak in Asia was in Bangkok in 1958 followed by other Asian countries. India experienced massive outbreaks of CHIK in the 1960s and early 70s mainly in cities. After a gap of 32 years an explosive outbreak of CHIK devastated the country affecting more than 1.4 million people in 13 states. The epidemic also witnessed many unusual clinico-pathological complications including CHIK associated deaths and mother to child transmission. High morbidity with severe arthralgia persisted for several months made the people mentally and physically weak. This review describes CHIK in general and highlights the various clinico-pathological aspects observed during the recent outbreak.

The histories of modern medical technologies have largely been studied exclusively within the biomedical context. Yet historians of medicine have increasingly demonstrated that a number of non-biomedical therapeutic traditions—Ayurvedic and Chinese medicine to name only two—have attained their own distinctive modernity. How has the incorporation of various medical technologies affected these neo-traditional medicines? What is the relationship between technologies and the body knowledge in non-biomedical therapeutics? Do shared technologies such as the stethoscope reveal the same bodily facts in biomedical and Ayurvedic contexts? These are some of the questions explored in this article by focusing on the uptake of the stethoscope in modern Ayurvedic medicine in Bengal. In the process the article also describes the emergence of a new sonic body in modern Ayurveda.

This book offers an in-depth account of malaria in South Asia. It examines the resurgence of malaria in the region towards the end of the twentieth century. It also covers past, present and future ways to curb, control and ultimately conquer malaria.